Severe acute respiratory syndrome coronavirus envelope protein ion channel activity promotes virus fitness and pathogenesis JL Nieto-Torres, ML DeDiego, C Verdiá-Báguena, JM Jimenez-Guardeño, ... PLoS pathogens 10 (5), e1004077, 2014 | 626 | 2014 |
Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome JL Nieto-Torres, C Verdiá-Báguena, JM Jimenez-Guardeño, ... Virology 485, 330-339, 2015 | 552 | 2015 |
Inhibition of NF-κB-mediated inflammation in severe acute respiratory syndrome coronavirus-infected mice increases survival ML DeDiego, JL Nieto-Torres, JA Regla-Nava, JM Jimenez-Guardeño, ... Journal of virology 88 (2), 913-924, 2014 | 438 | 2014 |
Subcellular location and topology of severe acute respiratory syndrome coronavirus envelope protein JL Nieto-Torres, ML DeDiego, E Álvarez, JM Jiménez-Guardeño, ... Virology 415 (2), 69-82, 2011 | 292 | 2011 |
Engineering a replication-competent, propagation-defective Middle East respiratory syndrome coronavirus as a vaccine candidate F Almazán, ML DeDiego, I Sola, S Zuñiga, JL Nieto-Torres, ... MBio 4 (5), 10.1128/mbio. 00650-13, 2013 | 275 | 2013 |
Role of severe acute respiratory syndrome coronavirus viroporins E, 3a, and 8a in replication and pathogenesis C Castaño-Rodriguez, JM Honrubia, J Gutiérrez-Álvarez, ML DeDiego, ... MBio 9 (3), 10.1128/mbio. 02325-17, 2018 | 263* | 2018 |
The PDZ-binding motif of severe acute respiratory syndrome coronavirus envelope protein is a determinant of viral pathogenesis JM Jimenez-Guardeño, JL Nieto-Torres, ML DeDiego, JA Regla-Nava, ... PLoS pathogens 10 (8), e1004320, 2014 | 263 | 2014 |
Coronavirus E protein forms ion channels with functionally and structurally-involved membrane lipids C Verdiá-Báguena, JL Nieto-Torres, A Alcaraz, ML DeDiego, J Torres, ... Virology 432 (2), 485-494, 2012 | 238 | 2012 |
Severe acute respiratory syndrome coronavirus envelope protein regulates cell stress response and apoptosis ML DeDiego, JL Nieto-Torres, JM Jiménez-Guardeño, JA Regla-Nava, ... PLoS pathogens 7 (10), e1002315, 2011 | 229 | 2011 |
Coronavirus virulence genes with main focus on SARS-CoV envelope gene ML DeDiego, JL Nieto-Torres, JM Jimenez-Guardeño, JA Regla-Nava, ... Virus research 194, 124-137, 2014 | 196 | 2014 |
Severe acute respiratory syndrome coronaviruses with mutations in the E protein are attenuated and promising vaccine candidates JA Regla-Nava, JL Nieto-Torres, JM Jimenez-Guardeño, ... Journal of virology 89 (7), 3870-3887, 2015 | 164 | 2015 |
Identification of the mechanisms causing reversion to virulence in an attenuated SARS-CoV for the design of a genetically stable vaccine JM Jimenez-Guardeño, JA Regla-Nava, JL Nieto-Torres, ML DeDiego, ... PLoS pathogens 11 (10), e1005215, 2015 | 160 | 2015 |
Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease J Netland, ML DeDiego, J Zhao, C Fett, E Álvarez, JL Nieto-Torres, ... Virology 399 (1), 120-128, 2010 | 156 | 2010 |
Analysis of SARS-CoV E protein ion channel activity by tuning the protein and lipid charge C Verdiá-Báguena, JL Nieto-Torres, A Alcaraz, ML DeDiego, L Enjuanes, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1828 (9), 2026-2031, 2013 | 107 | 2013 |
Relevance of viroporin ion channel activity on viral replication and pathogenesis JL Nieto-Torres, C Verdiá-Báguena, C Castaño-Rodriguez, VM Aguilella, ... Viruses 7 (7), 3552-3573, 2015 | 96 | 2015 |
Beyond autophagy: the expanding roles of ATG8 proteins JL Nieto-Torres, AM Leidal, J Debnath, M Hansen Trends in biochemical sciences 46 (8), 673-686, 2021 | 74 | 2021 |
The envelope protein of severe acute respiratory syndrome coronavirus interacts with the non-structural protein 3 and is ubiquitinated E Alvarez, ML DeDiego, JL Nieto-Torres, JM Jiménez-Guardeño, ... Virology 402 (2), 281-291, 2010 | 58 | 2010 |
Macroautophagy and aging: The impact of cellular recycling on health and longevity JL Nieto-Torres, M Hansen Molecular aspects of medicine 82, 101020, 2021 | 34 | 2021 |
LC3B phosphorylation regulates FYCO1 binding and directional transport of autophagosomes JL Nieto-Torres, SL Shanahan, R Chassefeyre, T Chaiamarit, S Zaretski, ... Current Biology 31 (15), 3440-3449. e7, 2021 | 33 | 2021 |
The replication of a mouse adapted SARS-CoV in a mouse cell line stably expressing the murine SARS-CoV receptor mACE2 efficiently induces the expression of proinflammatory … JA Regla-Nava, JM Jimenez-Guardeño, JL Nieto-Torres, TM Gallagher, ... Journal of virological methods 193 (2), 639-646, 2013 | 20 | 2013 |