| A SARS-CoV-2 protein interaction map reveals targets for drug repurposing DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ... Nature 583 (7816), 459-468, 2020 | 4376 | 2020 |
| Methylcytosine and normal cytosine deamination by the foreign DNA restriction enzyme APOBEC3A MA Carpenter, M Li, A Rathore, L Lackey, EK Law, AM Land, B Leonard, ... Journal of Biological Chemistry 287 (41), 34801-34808, 2012 | 153 | 2012 |
| Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity T Kouno, TV Silvas, BJ Hilbert, SMD Shandilya, MF Bohn, BA Kelch, ... Nature communications 8 (1), 15024, 2017 | 146 | 2017 |
| Crystal structure of the DNA cytosine deaminase APOBEC3F: the catalytically active and HIV-1 Vif-binding domain MF Bohn, SMD Shandilya, JS Albin, T Kouno, BD Anderson, ... Structure 21 (6), 1042-1050, 2013 | 119 | 2013 |
| The ssDNA mutator APOBEC3A is regulated by cooperative dimerization MF Bohn, SMD Shandilya, TV Silvas, EA Nalivaika, T Kouno, BA Kelch, ... Structure 23 (5), 903-911, 2015 | 98 | 2015 |
| Immunoproteasome functions explained by divergence in cleavage specificity and regulation MB Winter, F La Greca, S Arastu-Kapur, F Caiazza, P Cimermancic, ... Elife 6, e27364, 2017 | 84 | 2017 |
| Structural insight into SARS-CoV-2 neutralizing antibodies and modulation of syncytia D Asarnow, B Wang, WH Lee, Y Hu, CW Huang, B Faust, PML Ng, ... Cell 184 (12), 3192-3204. e16, 2021 | 67 | 2021 |
| Specificity for latent C termini links the E3 ubiquitin ligase CHIP to caspases M Ravalin, P Theofilas, K Basu, KA Opoku-Nsiah, VA Assimon, ... Nature chemical biology 15 (8), 786-794, 2019 | 61 | 2019 |
| A covalent inhibitor of K-Ras (G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy Z Zhang, PJ Rohweder, C Ongpipattanakul, K Basu, MF Bohn, EJ Dugan, ... Cancer Cell 40 (9), 1060-1069. e7, 2022 | 48 | 2022 |
| Ehlers–Danlos Syndrome Caused by Biallelic TNXB Variants in Patients with Congenital Adrenal Hyperplasia W Chen, AF Perritt, R Morissette, JL Dreiling, MF Bohn, A Mallappa, Z Xu, ... Human mutation 37 (9), 893-897, 2016 | 40 | 2016 |
| Global substrate specificity profiling of post‐translational modifying enzymes SL Ivry, NO Meyer, MB Winter, MF Bohn, GM Knudsen, AJ O'Donoghue, ... Protein Science 27 (3), 584-594, 2018 | 38 | 2018 |
| A computational analysis of the structural determinants of APOBEC3’s catalytic activity and vulnerability to HIV-1 Vif SMD Shandilya, MF Bohn, CA Schiffer Virology 471, 105-116, 2014 | 34 | 2014 |
| Bivalent binding of a fully human IgG to the SARS-CoV-2 spike proteins reveals mechanisms of potent neutralization B Wang, D Asarnow, WH Lee, CW Huang, B Faust, PML Ng, EZX Ngoh, ... BioRxiv, 2020 | 26 | 2020 |
| Structural determination of the broadly reactive anti-IGHV1-69 anti-idiotypic antibody G6 and its idiotope Y Avnir, KL Prachanronarong, Z Zhang, S Hou, EC Peterson, J Sui, ... Cell reports 21 (11), 3243-3255, 2017 | 21 | 2017 |
| Incidence and prevalence of coronavirus disease 2019 within a healthcare worker cohort during the first year of the severe acute respiratory syndrome coronavirus 2 pandemic SB Doernberg, M Holubar, V Jain, Y Weng, D Lu, JB Bollyky, H Sample, ... Clinical Infectious Diseases 75 (9), 1573-1584, 2022 | 20 | 2022 |
| Immunotargeting of nanocrystals by SpyCatcher conjugation of engineered antibodies CCS Pedroso, VR Mann, K Zuberbühler, MF Bohn, J Yu, V Altoe, ... ACS nano 15 (11), 18374-18384, 2021 | 18 | 2021 |
| Allosteric inhibitors, crystallography, and comparative analysis reveal network of coordinated movement across human herpesvirus proteases TM Acker, JE Gable, MF Bohn, P Jaishankar, MC Thompson, JS Fraser, ... Journal of the American Chemical Society 139 (34), 11650-11653, 2017 | 18 | 2017 |
| Generation of multivalent nanobody-based proteins with improved neutralization of long α-neurotoxins from elapid snakes J Wade, C Rimbault, H Ali, L Ledsgaard, E Rivera-de-Torre, ... Bioconjugate chemistry 33 (8), 1494-1504, 2022 | 14 | 2022 |
| A single-chain variable fragment selected against a conformational epitope of a recombinantly produced snake toxin using phage display C Rimbault, PD Knudsen, A Damsbo, K Boddum, H Ali, CM Hackney, ... New Biotechnology 76, 23-32, 2023 | 5 | 2023 |
| Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy CV Sørensen, L Ledsgaard, HHK Wildenauer, CH Dahl, TW Ebersole, ... Scientific Reports 13 (1), 10181, 2023 | 4 | 2023 |
Celia A SchifferProfessor and Chair of Biochemistry and Molecular Biotechnology, U Mass Chan Medical SchoolDirección de correo verificada de umassmed.edu
