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Janet Davies
Janet Davies
Post Doctoral Research Associate, King's College London
Verified email at kcl.ac.uk
Title
Cited by
Cited by
Year
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
B Ravikumar, C Vacher, Z Berger, JE Davies, S Luo, LG Oroz, F Scaravilli, ...
Nature genetics 36 (6), 585-595, 2004
28192004
Regulation of mammalian autophagy in physiology and pathophysiology
B Ravikumar, S Sarkar, JE Davies, M Futter, M Garcia-Arencibia, ...
Physiological reviews 90 (4), 1383-1435, 2010
20922010
Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and α-synuclein
S Sarkar, JE Davies, Z Huang, A Tunnacliffe, DC Rubinsztein
Journal of Biological Chemistry 282 (8), 5641-5652, 2007
12462007
Huntington's disease: from pathology and genetics to potential therapies
S Imarisio, J Carmichael, V Korolchuk, C Chen, S Saiki, C Rose, ...
Biochem. J 412, 191-209, 2008
5052008
Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases
S Luo, C Vacher, JE Davies, DC Rubinsztein
The Journal of cell biology 169 (4), 647-656, 2005
2562005
Trehalose reduces aggregate formation and delays pathology in a transgenic mouse model of oculopharyngeal muscular dystrophy
JE Davies, S Sarkar, DC Rubinsztein
Human molecular genetics 15 (1), 23, 2006
2332006
Doxycycline attenuates and delays toxicity of the oculopharyngeal muscular dystrophy mutation in transgenic mice
JE Davies, L Wang, L Garcia-Oroz, LJ Cook, C Vacher, DG O'Donovan, ...
Nature medicine 11 (6), 672-677, 2005
1702005
Molecular and phenotypic characterization of a mouse model of oculopharyngeal muscular dystrophy reveals severe muscular atrophy restricted to fast glycolytic fibres
C Trollet, SY Anvar, A Venema, IP Hargreaves, K Foster, A Vignaud, ...
Human molecular genetics 19 (11), 2191-2207, 2010
952010
The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxias
J Davies, S Sarkar, D Rubinsztein
BMC biochemistry 8 (Suppl 1), S2, 2007
792007
Cystamine suppresses polyalanine toxicity in a mouse model of oculopharyngeal muscular dystrophy
JE Davies, C Rose, S Sarkar, DC Rubinsztein
Science translational medicine 2 (34), 34ra40-34ra40, 2010
652010
Wild-type PABPN1 is anti-apoptotic and reduces toxicity of the oculopharyngeal muscular dystrophy mutation
JE Davies, S Sarkar, DC Rubinsztein
Human molecular genetics 17 (8), 1097, 2008
562008
Polyalanine and polyserine frameshift products in Huntington’s disease
JE Davies, DC Rubinsztein
Journal of medical genetics 43 (11), 893-896, 2006
562006
Autophagy in hypothalamic neurones of rats expressing a familial neurohypophysial diabetes insipidus transgene
J Davies, D Murphy
Journal of neuroendocrinology 14 (8), 629-637, 2002
552002
Endoplasmic reticulum derangement in hypothalamic neurons of rats expressing a familial neurohypophyseal diabetes insipidus mutant vasopressin transgene
SL Si-Hoe, FM De Bree, M Nijenhuis, JE Davies, LMC Howell, H Tinley, ...
The FASEB Journal 14 (12), 1680-1684, 2000
542000
Autophagy is a prosurvival mechanism in cells expressing an autosomal dominant familial neurohypophyseal diabetes insipidus mutant vasopressin transgene
R Castino, J Davies, S Beaucourt, C Isidoro, D Murphy
The FASEB journal 19 (8), 1021-1023, 2005
522005
Deleterious and protective properties of an aggregate-prone protein with a polyalanine expansion
Z Berger, JE Davies, S Luo, MY Pasco, I Majoul, CJ O'Kane, ...
Human molecular genetics 15 (3), 453, 2006
462006
Oculopharyngeal muscular dystrophy: potential therapies for an aggregate-associated disorder
JE Davies, Z Berger, DC Rubinsztein
The international journal of biochemistry & cell biology 38 (9), 1457-1462, 2006
382006
Over-expression of BCL2 rescues muscle weakness in a mouse model of oculopharyngeal muscular dystrophy
JE Davies, DC Rubinsztein
Human molecular genetics 20 (6), 1154, 2011
312011
Further delineation of the sequences required for the expression and physiological regulation of the vasopressin gene in transgenic rat hypothalamic magnocellular neurones
J Davies, S Waller, Q Zeng, S Wells, D Murphy
Journal of neuroendocrinology 15 (1), 42-50, 2003
272003
Towards a transgenic rat model of Familial Neurohypophysial Diabetes Insipidus
JE Davies
Bristol (United Kingdom): University of Bristol, 2002
2002
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