A simple method for improving protein solubility and long-term stability AP Golovanov, GM Hautbergue, SA Wilson, LY Lian Journal of the American Chemical Society 126 (29), 8933-8939, 2004 | 578 | 2004 |
Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed BJ Stevenson, J Bibby, P Pignatelli, S Muangnoicharoen, PM O’Neill, ... Insect biochemistry and molecular biology 41 (7), 492-502, 2011 | 271 | 2011 |
A Model for Human Cytochrome P450 2D6 Based on Homology Modeling and NMR Studies of Substrate Binding S Modi, MJ Paine, MJ Sutcliffe, LY Lian, WU Primrose, CR Wolf, ... Biochemistry 35 (14), 4540-4550, 1996 | 221 | 1996 |
Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP GM Hautbergue, ML Hung, AP Golovanov, LY Lian, SA Wilson Proceedings of the National Academy of Sciences 105 (13), 5154-5159, 2008 | 213 | 2008 |
A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation CF Oliver, S Modi, MJ Sutcliffe, WU Primrose, LY Lian, GCK Roberts Biochemistry 36 (7), 1567-1572, 1997 | 204 | 1997 |
Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8 Y Hargous, GM Hautbergue, AM Tintaru, L Skrisovska, AP Golovanov, ... The EMBO journal 25 (21), 5126-5137, 2006 | 194 | 2006 |
The catalytic mechanism of cytochrome P450 BM3 involves a 6 Å movement of the bound substrate on reduction S Modi, MJ Sutcliffe, WU Primrose, LY Lian, GCK Roberts Nature structural biology 3 (5), 414-417, 1996 | 169 | 1996 |
The catalytic mechanism of beta-lactamases: NMR titration of an active-site lysine residue of the TEM-1 enzyme. C Damblon, X Raquet, LY Lian, J Lamotte-Brasseur, E Fonze, P Charlier, ... Proceedings of the National Academy of Sciences 93 (5), 1747-1752, 1996 | 161 | 1996 |
A modulator of rho family G proteins, rhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm NH Keep, M Barnes, I Barsukov, R Badii, LY Lian, AW Segal, PCE Moody, ... Structure 5 (5), 623-633, 1997 | 160 | 1997 |
Labelling approaches for protein structural studies by solution-state and solid-state NMR LY Lian, DA Middleton Progress in Nuclear Magnetic Resonance Spectroscopy 39 (3), 171-190, 2001 | 156 | 2001 |
NMR studies of substrate binding to cytochrome P450 BM3: comparisons to cytochrome P450 cam S Modi, WU Primrose, JMB Boyle, CF Gibson, LY Lian, GCK Roberts Biochemistry 34 (28), 8982-8988, 1995 | 150 | 1995 |
Isolation and characterisation of two degradation products derived from the peptide antibiotic nisin WC Chan, BW Bycroft, LY Lian, GCK Roberts FEBS letters 252 (1-2), 29-36, 1989 | 149 | 1989 |
Structure‐activity relationships in the peptide antibiotic nisin: antibacterial activity of fragments of nisin WC Chan, M Leyland, J Clark, HM Dodd, LY Lian, MJ Gasson, BW Bycroft, ... FEBS letters 390 (2), 129-132, 1996 | 146 | 1996 |
[23] Protein-ligand interactions: Exchange processes and determination of ligand conformation and protein-ligand contacts LY Lian, IL Barsukov, MJ Sutcliffe, KH Sze, GCK Roberts Methods in enzymology 239, 657-700, 1994 | 137 | 1994 |
Crystal structure of the FMN-binding domain of human cytochrome P450 reductase at 1.93 Å resolution Q Zhao, S Modi, G Smith, M Paine, PD McDONAGH, CR Wolf, D Tew, ... Protein science 8 (2), 298-306, 1999 | 123 | 1999 |
Structure-activity relationships in the peptide antibiotic nisin: role of dehydroalanine 5 WC Chan, HM Dodd, N Horn, K Maclean, LY Lian, BW Bycroft, MJ Gasson, ... Applied and environmental microbiology 62 (8), 2966-2969, 1996 | 122 | 1996 |
1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine as a Substrate of Cytochrome P450 2D6: Allosteric Effects of NADPH− Cytochrome P450 Reductase S Modi, DE Gilham, MJ Sutcliffe, LY Lian, WU Primrose, CR Wolf, ... Biochemistry 36 (15), 4461-4470, 1997 | 117 | 1997 |
Engineering the substrate specificity of Bacillus megaterium cytochrome P-450 BM3: hydroxylation of alkyl trimethylammonium compounds FC OLIVER, S Modi, UW PRIMROSE, LY Lian, CKG ROBERTS Biochemical Journal 327 (2), 537-544, 1997 | 112 | 1997 |
Model for the complex between protein G and an antibody Fc fragment in solution K Kato, LY Lian, IL Barsukov, JP Derrick, HH Kim, R Tanaka, A Yoshino, ... Structure 3 (1), 79-85, 1995 | 111 | 1995 |
Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands CL Day, H Puthalakath, G Skea, A Strasser, I Barsukov, LY Lian, ... Biochemical Journal 377 (3), 597-605, 2004 | 104 | 2004 |