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Pilar Sánchez Gómez
Pilar Sánchez Gómez
Dirección de correo verificada de isciii.es - Página principal
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HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity
V Clement, P Sanchez, N de Tribolet, I Radovanovic, AR i Altaba
Current biology 17 (2), 165-172, 2007
13642007
Gli and hedgehog in cancer: tumours, embryos and stem cells
A Ruiz i Altaba, P Sánchez, N Dahmane
Nature Reviews Cancer 2 (5), 361-372, 2002
7812002
Sonic hedgehog controls stem cell behavior in the postnatal and adult brain
V Palma, DA Lim, N Dahmane, P Sánchez, TC Brionne, CD Herzberg, ...
Oxford University Press for The Company of Biologists Limited 132 (2), 335-344, 2005
7772005
Inhibition of prostate cancer proliferation by interference with SONIC HEDGEHOG-GLI1 signaling
P Sanchez, AM Hernández, B Stecca, AJ Kahler, AM DeGueme, A Barrett, ...
Proceedings of the National Academy of Sciences 101 (34), 12561-12566, 2004
6752004
The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis
N Dahmane, P Sánchez, Y Gitton, V Palma, T Sun, M Beyna, H Weiner, ...
Oxford University Press for The Company of Biologists Limited 128 (24), 5201 …, 2001
5982001
Pigment epithelium–derived factor is a niche signal for neural stem cell renewal
C Ramírez-Castillejo, F Sánchez-Sánchez, C Andreu-Agulló, SR Ferrón, ...
Nature neuroscience 9 (3), 331-339, 2006
5782006
The interaction of p62 with RIP links the atypical PKCs to NF‐κB activation
L Sanz, P Sanchez, MJ Lallena, MT Diaz‐Meco, J Moscat
The EMBO journal, 1999
4751999
The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C
MT Díaz-Meco, MM Municio, S Frutos, P Sanchez, J Lozano, L Sanz, ...
Cell 86 (5), 777-786, 1996
4741996
Evidence for a role of MEK and MAPK during signal transduction by protein kinase C zeta.
E Berra, MT Diaz‐Meco, J Lozano, S Frutos, MM Municio, P Sanchez, ...
The EMBO journal 14 (24), 6157-6163, 1995
3291995
Localization of atypical protein kinase C isoforms into lysosome-targeted endosomes through interaction with p62
P Sanchez, G De Carcer, IV Sandoval, J Moscat, MT Diaz-Meco
Molecular and cellular biology 18 (5), 3069-3080, 1998
2861998
Pathways and consequences: Hedgehog signaling in human disease
JL Mullor, P Sánchez, AR i Altaba
Trends in cell biology 12 (12), 562-569, 2002
2222002
In vivo inhibition of endogenous brain tumors through systemic interference of Hedgehog signaling in mice
P Sanchez, AR i Altaba
Mechanisms of development 122 (2), 223-230, 2005
179*2005
Inhibition of DYRK1A destabilizes EGFR and reduces EGFR-dependent glioblastoma growth
N Pozo, C Zahonero, P Fernández, JM Liñares, A Ayuso, M Hagiwara, ...
The Journal of clinical investigation 123 (6), 2475-2487, 2013
1502013
Lambda-interacting protein, a novel protein that specifically interacts with the zinc finger domain of the atypical protein kinase C isotype λ/ι and stimulates its kinase …
MT Diaz-Meco, MM Municio, P Sanchez, J Lozano, J Moscat
Molecular and cellular biology, 1996
1491996
Glioblastoma on a microfluidic chip: Generating pseudopalisades and enhancing aggressiveness through blood vessel obstruction events.
FLJ Ayuso JM, Monge R, Martínez-González A, Virumbrales-Muñoz M, Llamazares ...
Neuro Oncology 19 (4), 503-513, 2017
1332017
Hedgehog–Gli signaling in brain tumors: stem cells and paradevelopmental programs in cancer
AR i Altaba, B Stecca, P Sánchez
Cancer letters 204 (2), 145-157, 2004
1242004
Therapeutic targeting of the Hedgehog-GLI pathway in prostate cancer
P Sanchez, V Clement, A Ruiz i Altaba
Cancer research 65 (8), 2990-2992, 2005
1182005
Phase II trial of dacomitinib, a pan–human EGFR tyrosine kinase inhibitor, in recurrent glioblastoma patients with EGFR amplification
JM Sepúlveda-Sánchez, MÁ Vaz, C Balañá, M Gil-Gil, G Reynés, ...
Neuro-oncology 19 (11), 1522-1531, 2017
1142017
DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis
P Fernandez-Martinez, C Zahonero, P Sánchez-Gómez
Molecular & cellular oncology 2 (1), e970048, 2015
1142015
A combined ex/in vivo assay to detect effects of exogenously added factors in neural stem cells
SR Ferrón, C Andreu-Agulló, H Mira, P Sánchez, ...
Nature protocols 2 (4), 849-859, 2007
1092007
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