| Correction of the ΔF508 mutation in the cystic fibrosis transmembrane conductance regulator gene by zinc-finger nuclease homology-directed repair CM Lee, R Flynn, JA Hollywood, MF Scallan, PT Harrison BioResearch open access 1 (3), 99-108, 2012 | 140 | 2012 |
| Two distinct regions of FC gamma RI initiate separate signalling pathways involved in endocytosis and phagocytosis. W Davis, PT Harrison, MJ Hutchinson, JM Allen The EMBO journal 14 (3), 432-441, 1995 | 136 | 1995 |
| C‐reactive protein‐mediated phagocytosis and phospholipase D signalling through the high‐affinity receptor for immunoglobulin G (FcγRI) KB Bodman‐Smith, AJ Melendez, I Campbell, PT Harrison, JM Allen, ... Immunology 107 (2), 252-260, 2002 | 124 | 2002 |
| Binding of monomeric immunoglobulin G triggers Fc gamma RI-mediated endocytosis. PT Harrison, W Davis, JC Norman, AR Hockaday, JM Allen Journal of Biological Chemistry 269 (39), 24396-24402, 1994 | 122 | 1994 |
| Repeated cleaning of protein A affinity column with sodium hydroxide G Hale, A Drumm, P Harrison, J Phillips Journal of immunological methods 171 (1), 15-21, 1994 | 111 | 1994 |
| Prime editing–an update on the field J Scholefield, PT Harrison Gene Therapy 28 (7), 396-401, 2021 | 110 | 2021 |
| Cas9/gRNA targeted excision of cystic fibrosis-causing deep-intronic splicing mutations restores normal splicing of CFTR mRNA DJ Sanz, JA Hollywood, MF Scallan, PT Harrison PloS one 12 (9), e0184009, 2017 | 103 | 2017 |
| Viral vectors in cancer immunotherapy: which vector for which strategy? SA Collins, B Guinn, PT Harrison, MF Scallan, GC O'Sullivan, M Tangney Current gene therapy 8 (2), 66-78, 2008 | 103 | 2008 |
| Evolution of herpesvirus thymidine kinases from cellular deoxycytidine kinase PT Harrison, R Thompson, AJ Davison Journal of general virology 72 (10), 2583-2586, 1991 | 68 | 1991 |
| Manufacture and quality control of CAMPATH-1 antibodies for clinical trials J Phillips, A Drumm, P Harrison, P Bird, K Bhamra, E Berrie, G Hale Cytotherapy 3 (3), 233-242, 2001 | 64 | 2001 |
| Use of human induced pluripotent stem cells and kidney organoids to develop a cysteamine/mTOR inhibition combination therapy for cystinosis JA Hollywood, A Przepiorski, RF D’Souza, S Sreebhavan, EJ Wolvetang, ... Journal of the american society of nephrology 31 (5), 962-982, 2020 | 63 | 2020 |
| Genetic medicines for CF: Hype versus reality EWFW Alton, AC Boyd, JC Davies, DR Gill, U Griesenbach, PT Harrison, ... Pediatric Pulmonology 51 (S44), S5-S17, 2016 | 60 | 2016 |
| FcγRIIa expression with FcγRI results in C-reactive protein-and IgG-mediated phagocytosis KB Bodman-Smith, RE Gregory, PT Harrison, JG Raynes Journal of Leucocyte Biology 75 (6), 1029-1035, 2004 | 60 | 2004 |
| Genetic therapies for cystic fibrosis lung disease SL Hart, PT Harrison Current Opinion in Pharmacology 34, 119-124, 2017 | 46 | 2017 |
| Domain swap chimeras to study the binding of IgG by FcγRI, the high affinity receptor for IgG PT Harrison, JM Allen Biochemical Society Transactions 24 (1), 144S-144S, 1996 | 46 | 1996 |
| High affinity IgG binding by FcgammaRI (CD64) is modulated by two distinct IgSF domains and the transmembrane domain of the receptor. PT Harrison, JM Allen Protein engineering 11 (3), 225-232, 1998 | 38 | 1998 |
| Analysis of gene repair tracts from Cas9/gRNA double-stranded breaks in the human CFTR gene JA Hollywood, CM Lee, MF Scallan, PT Harrison Scientific Reports 6 (1), 32230, 2016 | 37 | 2016 |
| Effects of GDF5 overexpression on embryonic rat dopaminergic neurones in vitro and in vivo DB O’Sullivan, PT Harrison, AM Sullivan Journal of neural transmission 117, 559-572, 2010 | 36 | 2010 |
| Gene and base editing as a therapeutic option for cystic fibrosis—Learning from other diseases K Mention, L Santos, PT Harrison Genes 10 (5), 387, 2019 | 34 | 2019 |
| The regulation of monoamine oxidase a gene expression by distinct variable number tandem repeats M Manca, V Pessoa, AI Lopez, PT Harrison, F Miyajima, H Sharp, ... Journal of Molecular Neuroscience 64, 459-470, 2018 | 34 | 2018 |
