| Ryanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease B Oulès, D Del Prete, B Greco, X Zhang, I Lauritzen, J Sevalle, S Moreno, ... Journal of Neuroscience 32 (34), 11820-11834, 2012 | 254 | 2012 |
| STIM1 and Orai1 mediate CRAC channel activity and are essential for human glioblastoma invasion RK Motiani, MC Hyzinski-García, X Zhang, MM Henkel, IF Abdullaev, ... Pflügers Archiv-European Journal of Physiology 465, 1249-1260, 2013 | 208 | 2013 |
| TWIK-1 and TREK-1 are potassium channels contributing significantly to astrocyte passive conductance in rat hippocampal slices M Zhou, G Xu, M Xie, X Zhang, GP Schools, L Ma, HK Kimelberg, H Chen Journal of Neuroscience 29 (26), 8551-8564, 2009 | 204 | 2009 |
| Orai3 is an estrogen receptor α-regulated Ca2+ channel that promotes tumorigenesis RK Motiani, X Zhang, KE Harmon, RS Keller, K Matrougui, JA Bennett, ... The FASEB Journal 27 (1), 63-75, 2012 | 196 | 2012 |
| Orai1-mediated ICRAC is essential for neointima formation after vascular injury W Zhang, KE Halligan, X Zhang, JM Bisaillon, JC Gonzalez-Cobos, ... Circulation research 109 (5), 534-542, 2011 | 151 | 2011 |
| Store-Independent Orai1/3 Channels Activated by Intracrine LeukotrieneC4: Role in Neointimal Hyperplasia JC González-Cobos, X Zhang, W Zhang, B Ruhle, RK Motiani, R Schindl, ... Circulation research 112 (7), 1013-1025, 2013 | 141 | 2013 |
| Multiple types of calcium channels arising from alternative translation initiation of the Orai1 message PN Desai, X Zhang, S Wu, A Janoshazi, S Bolimuntha, JW Putney, ... Science Signaling 8 (387), ra74, 2015 | 136 | 2015 |
| The native ORAI channel trio underlies the diversity of Ca2+ signaling events. Ryan E. Yoast, Scott M. Emrich, Xuexin Zhang, Ping Xin, Martin T. Johnson ... Nature Communications, 2020 | 111 | 2020 |
| Airway smooth muscle STIM1 and Orai1 are upregulated in asthmatic mice and mediate PDGF-activated SOCE, CRAC currents, proliferation, and migration AM Spinelli, JC González-Cobos, X ZHANG, RK Motiani, S Rowan, ... Pflügers Archiv-European Journal of Physiology 464 (5), 481-492, 2012 | 104 | 2012 |
| Mitochondria control store‐operated Ca2+ entry through Na+ and redox signals TBK Nissim, X ZHANG, A Elazar, S Roy, JA Stolwijk, Y Zhou, RK Motiani, ... The EMBO journal 36 (6), 797-815, 2017 | 100 | 2017 |
| Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels Xuexin Zhang, Ping Xin, Ryan E. Yoast, Scott M. Emrich, Martin T. Johnson ... Cell Calcium, 2020 | 96 | 2020 |
| STIM1 controls endothelial barrier function independently of Orai1 and Ca2+ entry AV Shinde, RK Motiani, X Zhang, IF Abdullaev, AP Adam, ... Science signaling 6 (267), ra18-ra18, 2013 | 91 | 2013 |
| Urotensin-II Promotes Vascular Smooth Muscle Cell Proliferation Through Store Operated Calcium Entry And EGFR Transactivation TS María Rodríguez-Moyano, Ignacio Díaz, Natalia Cardiovascular Research, 2013 | 89 | 2013 |
| A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction X ZHANG, T Pathak, R Yoast, S Emrich, P Xin, R Nwokonko, M Johnson, ... Nature Communications, 2019 | 86 | 2019 |
| Complex role of STIM1 in the activation of store-independent Orai1/3 channels X ZHANG, W Zhang, JC González-Cobos, I Jardin, C Romanin, ... The Journal of general physiology 143 (3), 345-359, 2014 | 85 | 2014 |
| TWIK-1 two-pore domain potassium channels change ion selectivity and conduct inward leak sodium currents in hypokalemia L Ma, X Zhang, H Chen Science signaling 4 (176), ra37-ra37, 2011 | 83 | 2011 |
| Enhanced Ca2+ entry due to Orai1 plasma membrane insertion increases IL-8 secretion by cystic fibrosis airways H Balghi, R Robert, B Rappaz, X Zhang, A Wohlhuter-Haddad, ... The FASEB Journal 25 (12), 4274-4291, 2011 | 77 | 2011 |
| Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ Z Liu, Y Wei, L Zhang, PP Yee, M Johnson, X Zhang, M Gulley, ... Oncogene 38 (1), 120-139, 2019 | 66 | 2019 |
| Mechanisms of STIM1 Activation of Store-Independent LeukotrieneC4-Regulated Ca2+ Channels X ZHANG, JC González-Cobos, R Schindl, M Muik, B Ruhle, RK Motiani, ... Molecular and cellular biology 33 (16), 2013 | 65 | 2013 |
| Acid-sensitive TWIK and TASK two-pore domain potassium channels change ion selectivity and become permeable to sodium in extracellular acidification L Ma, X Zhang, M Zhou, H Chen Journal of Biological Chemistry 287 (44), 37145-37153, 2012 | 63 | 2012 |
Mohamed TrebakProfessor, Pharmacology & Chemical Biology, University of PittsburghVerified email at pitt.edu
