Raquel L. Lieberman
Raquel L. Lieberman
Dirección de correo verificada de chemistry.gatech.edu
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Crystal structure of a membrane-bound metalloenzyme that catalyses the biological oxidation of methane
RL Lieberman, AC Rosenzweig
Nature 434 (7030), 177-182, 2005
5982005
Structure of acid β-glucosidase with pharmacological chaperone provides insight into Gaucher disease
RL Lieberman, BA Wustman, P Huertas, AC Powe, CW Pine, R Khanna, ...
Nature chemical biology 3 (2), 101-107, 2007
2312007
Biological methane oxidation: regulation, biochemistry, and active site structure of particulate methane monooxygenase
RL Lieberman, AC Rosenzweig
Critical reviews in biochemistry and molecular biology 39 (3), 147-164, 2004
2202004
Automated structure-and sequence-based design of proteins for high bacterial expression and stability
A Goldenzweig, M Goldsmith, SE Hill, O Gertman, P Laurino, Y Ashani, ...
Molecular cell 63 (2), 337-346, 2016
1472016
Purified particulate methane monooxygenase from Methylococcus capsulatus (Bath) is a dimer with both mononuclear copper and a copper-containing cluster
RL Lieberman, DB Shrestha, PE Doan, BM Hoffman, TL Stemmler, ...
Proceedings of the National Academy of Sciences 100 (7), 3820-3825, 2003
1442003
Effects of pH and iminosugar pharmacological chaperones on lysosomal glycosidase structure and stability
RL Lieberman, JA D’aquino, D Ringe, GA Petsko
Biochemistry 48 (22), 4816-4827, 2009
1322009
Characterization of the particulate methane monooxygenase metal centers in multiple redox states by X-ray absorption spectroscopy
RL Lieberman, KC Kondapalli, DB Shrestha, AS Hakemian, SM Smith, ...
Inorganic chemistry 45 (20), 8372-8381, 2006
932006
Detection of ligand binding hot spots on protein surfaces via fragment-based methods: application to DJ-1 and glucocerebrosidase
MR Landon, RL Lieberman, QQ Hoang, S Ju, JMM Caaveiro, SD Orwig, ...
Journal of computer-aided molecular design 23 (8), 491-500, 2009
832009
Crystal Structure of a Novel Red Copper Protein from Nitrosomonas europaea,
RL Lieberman, DM Arciero, AB Hooper, AC Rosenzweig
Biochemistry 40 (19), 5674-5681, 2001
752001
Consensus recommendations for trabecular meshwork cell isolation, characterization and culture
KE Keller, SK Bhattacharya, T Borrás, TM Brunner, S Chansangpetch, ...
Experimental eye research 171, 164-173, 2018
622018
X-ray crystallography and biological metal centers: Is seeing believing?
M Sommerhalter, RL Lieberman, AC Rosenzweig
Inorganic chemistry 44 (4), 770-778, 2005
602005
Glucose-regulated protein 94 triage of mutant myocilin through endoplasmic reticulum-associated degradation subverts a more efficient autophagic clearance mechanism
A Suntharalingam, JF Abisambra, JC O'Leary, J Koren, B Zhang, MK Joe, ...
Journal of Biological Chemistry 287 (48), 40661-40669, 2012
522012
The quest for the particulate methane monooxygenase active site
RL Lieberman, AC Rosenzweig
Dalton Trans., 3390-3396, 2005
512005
Structural basis for misfolding in myocilin-associated glaucoma
RK Donegan, SE Hill, DM Freeman, E Nguyen, SD Orwig, KC Turnage, ...
Human molecular genetics 24 (8), 2111-2124, 2015
482015
The stability of myocilin olfactomedin domain variants provides new insight into glaucoma as a protein misfolding disorder
JN Burns, KC Turnage, CA Walker, RL Lieberman
Biochemistry 50 (26), 5824-5833, 2011
482011
Rescue of glaucoma-causing mutant myocilin thermal stability by chemical chaperones
JN Burns, SD Orwig, JL Harris, JD Watkins, D Vollrath, RL Lieberman
ACS chemical biology 5 (5), 477-487, 2010
472010
Crystallization chaperone strategies for membrane proteins
RL Lieberman, JA Culver, KC Entzminger, JC Pai, JA Maynard
Methods 55 (4), 293-302, 2011
432011
Amyloid fibril formation by the glaucoma-associated olfactomedin domain of myocilin
SD Orwig, CW Perry, LY Kim, KC Turnage, R Zhang, D Vollrath, ...
Journal of molecular biology 421 (2-3), 242-255, 2012
412012
A guided tour of the structural biology of Gaucher disease: Acid-β-glucosidase and saposin C
RL Lieberman
Enzyme research 2011, 2011
412011
Binding of 3, 4, 5, 6-tetrahydroxyazepanes to the acid-β-glucosidase active site: implications for pharmacological chaperone design for Gaucher disease
SD Orwig, YL Tan, NP Grimster, Z Yu, ET Powers, JW Kelly, ...
Biochemistry 50 (49), 10647-10657, 2011
392011
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Artículos 1–20