GONZALO PELUFFO
GONZALO PELUFFO
CEINBIO; Departamento de Bioquímica, Facultad de Medicina, Universidad de la República
Verified email at fmed.edu.uy
TitleCited byYear
Unraveling peroxynitrite formation in biological systems
R Radi, G Peluffo, MN Alvarez, M Naviliat, A Cayota
Free Radical Biology and Medicine 30 (5), 463-488, 2001
7992001
Protein tyrosine nitration—functional alteration or just a biomarker?
JM Souza, G Peluffo, R Radi
Free Radical Biology and Medicine 45 (4), 357-366, 2008
3812008
Biochemistry of protein tyrosine nitration in cardiovascular pathology
G Peluffo, R Radi
Cardiovascular research 75 (2), 291-302, 2007
2982007
Xanthine Oxidase-mediated Decomposition ofS-Nitrosothiols
M Trujillo, MN Alvarez, G Peluffo, BA Freeman, R Radi
Journal of Biological Chemistry 273 (14), 7828-7834, 1998
2181998
1,2,5-Oxadiazole N-Oxide Derivatives and Related Compounds as Potential Antitrypanosomal Drugs:  Structure−Activity Relationships
H Cerecetto, R Di Maio, M González, M Risso, P Saenz, G Seoane, ...
Journal of medicinal chemistry 42 (11), 1941-1950, 1999
1711999
Intraphagosomal peroxynitrite as a macrophage-derived cytotoxin against internalized trypanosoma cruzi consequences for oxidative killing and role of microbial peroxiredoxins …
MN Alvarez, G Peluffo, L Piacenza, R Radi
Journal of Biological Chemistry 286 (8), 6627-6640, 2011
1622011
L-arginine-dependent suppression of apoptosis in Trypanosoma cruzi: contribution of the nitric oxide and polyamine pathways
L Piacenza, G Peluffo, R Radi
Proceedings of the National Academy of Sciences 98 (13), 7301-7306, 2001
1412001
Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase overexpression
L Piacenza, F Irigoín, MN Alvarez, G Peluffo, MC Taylor, JM Kelly, ...
Biochemical Journal 403 (2), 323-334, 2007
1382007
Nitric oxide-derived oxidants with a focus on peroxynitrite: molecular targets, cellular responses and therapeutic implications
P Calcerrada, G Peluffo, R Radi
Current pharmaceutical design 17 (35), 3905-3932, 2011
1352011
Protein tyrosine nitration in hydrophilic and hydrophobic environments
S Bartesaghi, G Ferrer-Sueta, G Peluffo, V Valez, H Zhang, ...
Amino acids 32 (4), 501-515, 2007
1312007
Synthesis and antitrypanosomal evaluation of E-isomers of 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives. Structure–activity relationships.
H Cerecetto, R Di Maio, M González, M Risso, G Sagrera, G Seoane, ...
European journal of medicinal chemistry 35 (3), 343-350, 2000
1242000
Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage-and endogenously-derived peroxynitrite
L Piacenza, G Peluffo, MN Alvarez, JM Kelly, SR Wilkinson, R Radi
Biochemical Journal 410 (2), 359-368, 2008
1232008
Macrophage-derived peroxynitrite diffusion and toxicity to Trypanosoma cruzi
MN Alvarez, L Piacenza, F Irigoín, G Peluffo, R Radi
Archives of Biochemistry and Biophysics 432 (2), 222-232, 2004
1222004
Fighting the oxidative assault: the Trypanosoma cruzi journey to infection
L Piacenza, MN Alvarez, G Peluffo, R Radi
Current opinion in microbiology 12 (4), 415-421, 2009
1142009
Enhanced mitochondrial superoxide in hyperglycemic endothelial cells: direct measurements and formation of hydrogen peroxide and peroxynitrite
C Quijano, L Castro, G Peluffo, V Valez, R Radi
American Journal of Physiology-Heart and Circulatory Physiology 293 (6 …, 2007
1142007
Enzymes of the antioxidant network as novel determiners of Trypanosoma cruzi virulence
L Piacenza, MP Zago, G Peluffo, MN Alvarez, MA Basombrio, R Radi
International journal for parasitology 39 (13), 1455-1464, 2009
1102009
Synthesis and anti-trypanosomal activity of novel 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives
H Cerecetto, R Di Maio, G Ibarruri, G Seoane, A Denicola, G Peluffo, ...
Il farmaco 53 (2), 89-94, 1998
941998
Superoxide-mediated inactivation of nitric oxide and peroxynitrite formation by tobacco smoke in vascular endothelium: studies in cultured cells and smokers
G Peluffo, P Calcerrada, L Piacenza, N Pizzano, R Radi
American Journal of Physiology-Heart and Circulatory Physiology 296 (6 …, 2009
842009
Mechanistic studies of peroxynitrite-mediated tyrosine nitration in membranes using the hydrophobic probe Nt-BOC-L-tyrosine tert-butyl ester
S Bartesaghi, V Valez, M Trujillo, G Peluffo, N Romero, H Zhang, ...
Biochemistry 45 (22), 6813-6825, 2006
812006
Septic diaphragmatic dysfunction is prevented by Mn (III) porphyrin therapy and inducible nitric oxide synthase inhibition
N Nin, A Cassina, J Boggia, E Alfonso, H Botti, G Peluffo, A Trostchansky, ...
Intensive care medicine 30 (12), 2271-2278, 2004
702004
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