Unraveling peroxynitrite formation in biological systems R Radi, G Peluffo, MN Alvarez, M Naviliat, A Cayota Free Radical Biology and Medicine 30 (5), 463-488, 2001 | 962 | 2001 |
Protein tyrosine nitration—functional alteration or just a biomarker? JM Souza, G Peluffo, R Radi Free Radical Biology and Medicine 45 (4), 357-366, 2008 | 487 | 2008 |
Biochemistry of protein tyrosine nitration in cardiovascular pathology G Peluffo, R Radi Cardiovascular research 75 (2), 291-302, 2007 | 359 | 2007 |
Intraphagosomal peroxynitrite as a macrophage-derived cytotoxin against internalized Trypanosoma cruzi: consequences for oxidative killing and role of microbial peroxiredoxins … MN Alvarez, G Peluffo, L Piacenza, R Radi Journal of Biological Chemistry 286 (8), 6627-6640, 2011 | 260 | 2011 |
Xanthine oxidase-mediated decomposition of S-nitrosothiols M Trujillo, MN Alvarez, G Peluffo, BA Freeman, R Radi Journal of Biological Chemistry 273 (14), 7828-7834, 1998 | 257 | 1998 |
Nitric oxide-derived oxidants with a focus on peroxynitrite: molecular targets, cellular responses and therapeutic implications P Calcerrada, G Peluffo, R Radi Current pharmaceutical design 17 (35), 3905-3932, 2011 | 194 | 2011 |
1,2,5-Oxadiazole N-Oxide Derivatives and Related Compounds as Potential Antitrypanosomal Drugs: Structure−Activity Relationships H Cerecetto, R Di Maio, M González, M Risso, P Saenz, G Seoane, ... Journal of medicinal chemistry 42 (11), 1941-1950, 1999 | 191 | 1999 |
Mitochondrial superoxide radicals mediate programmed cell death in Trypanosoma cruzi: cytoprotective action of mitochondrial iron superoxide dismutase … L Piacenza, F Irigoín, MN Alvarez, G Peluffo, MC Taylor, JM Kelly, ... Biochemical Journal 403 (2), 323-334, 2007 | 180 | 2007 |
Peroxiredoxins play a major role in protecting Trypanosoma cruzi against macrophage- and endogenously-derived peroxynitrite L Piacenza, G Peluffo, MN Alvarez, JM Kelly, SR Wilkinson, R Radi Biochemical Journal 410 (2), 359-368, 2008 | 176 | 2008 |
Enhanced mitochondrial superoxide in hyperglycemic endothelial cells: direct measurements and formation of hydrogen peroxide and peroxynitrite C Quijano, L Castro, G Peluffo, V Valez, R Radi American Journal of Physiology-Heart and Circulatory Physiology 293 (6 …, 2007 | 167 | 2007 |
Protein tyrosine nitration in hydrophilic and hydrophobic environments S Bartesaghi, G Ferrer-Sueta, G Peluffo, V Valez, H Zhang, ... Amino acids 32, 501-515, 2007 | 163 | 2007 |
Macrophage-derived peroxynitrite diffusion and toxicity to Trypanosoma cruzi MN Alvarez, L Piacenza, F Irigoín, G Peluffo, R Radi Archives of biochemistry and biophysics 432 (2), 222-232, 2004 | 162 | 2004 |
l-Arginine-dependent suppression of apoptosis in Trypanosoma cruzi: Contribution of the nitric oxide and polyamine pathways L Piacenza, G Peluffo, R Radi Proceedings of the National Academy of Sciences 98 (13), 7301-7306, 2001 | 162 | 2001 |
Fighting the oxidative assault: the Trypanosoma cruzi journey to infection L Piacenza, MN Alvarez, G Peluffo, R Radi Current opinion in microbiology 12 (4), 415-421, 2009 | 154 | 2009 |
Enzymes of the antioxidant network as novel determiners of Trypanosoma cruzi virulence L Piacenza, MP Zago, G Peluffo, MN Alvarez, MA Basombrio, R Radi International journal for parasitology 39 (13), 1455-1464, 2009 | 152 | 2009 |
Synthesis and antitrypanosomal evaluation of E-isomers of 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives. Structure–activity relationships. H Cerecetto, R Di Maio, M González, M Risso, G Sagrera, G Seoane, ... European journal of medicinal chemistry 35 (3), 343-350, 2000 | 134 | 2000 |
Trypanosoma cruzi Antioxidant Enzymes As Virulence Factors in Chagas Disease L Piacenza, G Peluffo, MN Alvarez, A Martínez, R Radi Antioxidants & Redox Signaling 19 (7), 723-734, 2013 | 132 | 2013 |
Superoxide-mediated inactivation of nitric oxide and peroxynitrite formation by tobacco smoke in vascular endothelium: studies in cultured cells and smokers G Peluffo, P Calcerrada, L Piacenza, N Pizzano, R Radi American Journal of Physiology-Heart and Circulatory Physiology 296 (6 …, 2009 | 129 | 2009 |
Mechanistic studies of peroxynitrite-mediated tyrosine nitration in membranes using the hydrophobic probe Nt-BOC-L-tyrosine tert-butyl ester S Bartesaghi, V Valez, M Trujillo, G Peluffo, N Romero, H Zhang, ... Biochemistry 45 (22), 6813-6825, 2006 | 98 | 2006 |
Synthesis and anti-trypanosomal activity of novel 5-nitro-2-furaldehyde and 5-nitrothiophene-2-carboxaldehyde semicarbazone derivatives H Cerecetto, R Di Maio, G Ibarruri, G Seoane, A Denicola, G Peluffo, ... Il farmaco 53 (2), 89-94, 1998 | 98 | 1998 |