| Germline signaling mediates the synergistically prolonged longevity produced by double mutations in daf-2 and rsks-1 in C. elegans D Chen, PWL Li, BA Goldstein, W Cai, EL Thomas, F Chen, AE Hubbard, ... Cell reports 5 (6), 1600-1610, 2013 | 143 | 2013 |
| Icariin and its derivative icariside II extend healthspan via insulin/IGF-1 pathway in C. elegans WJ Cai, JH Huang, SQ Zhang, B Wu, P Kapahi, XM Zhang, ZY Shen PloS one 6 (12), e28835, 2011 | 123 | 2011 |
| The associations between Parkinson’s disease and cancer: the plot thickens DD Feng, W Cai, X Chen Translational neurodegeneration 4, 1-14, 2015 | 96 | 2015 |
| Icariin intervenes in cardiac inflammaging through upregulation of SIRT6 enzyme activity and inhibition of the NF-kappa B pathway Y Chen, T Sun, J Wu, B Kalionis, C Zhang, D Yuan, J Huang, W Cai, ... BioMed research international 2015, 2015 | 74 | 2015 |
| Icariin improves cognitive deficits and activates quiescent neural stem cells in aging rats B Wu, Y Chen, J Huang, Y Ning, Q Bian, Y Shan, W Cai, X Zhang, Z Shen Journal of ethnopharmacology 142 (3), 746-753, 2012 | 59 | 2012 |
| The melanoma‐linked “redhead” MC1R influences dopaminergic neuron survival X Chen, H Chen, W Cai, M Maguire, B Ya, F Zuo, R Logan, H Li, ... Annals of neurology 81 (3), 395-406, 2017 | 53 | 2017 |
| Icariin, a natural flavonol glycoside, extends healthspan in mice SQ Zhang, WJ Cai, JH Huang, B Wu, SJ Xia, XL Chen, XM Zhang, ... Experimental Gerontology 69, 226-235, 2015 | 38 | 2015 |
| Pyrroloquinoline quinone enhances the resistance to oxidative stress and extends lifespan upon DAF-16 and SKN-1 activities in C. elegans JZ Wu, JH Huang, R Khanabdali, B Kalionis, SJ Xia, WJ Cai Experimental Gerontology 80, 43-50, 2016 | 36 | 2016 |
| An efficient and novel screening model for assessing the bioactivity of extracts against multidrug-resistant Pseudomonas aeruginosa using Caenorhabditis elegans Y Zhou, L Shao, J Li, L Han, W Cai, C Zhu, D Chen Bioscience, biotechnology, and biochemistry 75 (9), 1746-1751, 2011 | 33 | 2011 |
| Bimolecular fluorescence complementation of alpha-synuclein demonstrates its oligomerization with dopaminergic phenotype in mice W Cai, D Feng, MA Schwarzschild, PJ McLean, X Chen EBioMedicine 29, 13-22, 2018 | 30 | 2018 |
| Icariin inhibits LPS-induced cell inflammatory response by promoting GRα nuclear translocation and upregulating GRα expression X Sun, X Deng, W Cai, W Li, Z Shen, T Jiang, J Huang Life sciences 195, 33-43, 2018 | 27 | 2018 |
| Icariin promotes self-renewal of neural stem cells: an involvement of extracellular regulated kinase signaling pathway J Huang, W Cai, X Zhang, Z Shen Chinese journal of integrative medicine 20 (2), 107-115, 2014 | 27 | 2014 |
| Icaritin enhances mESC self-renewal through upregulating core pluripotency transcription factors mediated by ERα WP Tsang, F Zhang, Q He, W Cai, J Huang, WY Chan, Z Shen, C Wan Scientific reports 7 (1), 40894, 2017 | 20 | 2017 |
| 中医药治疗变应性鼻炎辨证用药特点及分析 程坚， 蔡外娇， 张新民 中华中医药杂志 27 (7), 1947-1950, 2012 | 16 | 2012 |
| 淫羊霍总黄酮延缓秀丽隐杆线虫衰老的实验研究 蔡外娇， 张新民， 黄建华， 沈自尹 | 16 | 2008 |
| Effect of Epimedium flavonoids in retarding aging of C. elegans WJ Cai, XM Zhang, JH Huang Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi Jiehe Zazhi= Chinese …, 2008 | 13 | 2008 |
| Melanocortin 1 receptor activation protects against alpha-synuclein pathologies in models of Parkinson’s disease W Cai, P Srivastava, D Feng, Y Lin, CR Vanderburg, Y Xu, P Mclean, ... Molecular neurodegeneration 17 (1), 16, 2022 | 10 | 2022 |
| Shen-Jing as a Chinese medicine concept might be a counterpart of stem cells in regenerative medicine Y Ren, J Huang, W Cai, Z Shen Chinese journal of integrative medicine 25 (1), 64-70, 2019 | 9 | 2019 |
| Inhibition of PAR-1 delays aging via activating AMPK in C. elegans D Wu, W Cai, X Zhang, J Lan, L Zou, SJ Chen, Z Wu, D Chen Aging (Albany NY) 12 (24), 25700, 2020 | 6 | 2020 |
| 一种中药单体小复方对变应性鼻炎模型小鼠的免疫调节作用 程坚， 张新民， 沈自尹， 陈伟华， 蔡外娇， 应健， 胡国让， 刘闰红 Journal of Integrative Medicine 9 (12), 1360-1366, 2018 | 6 | 2018 |
Pankaj KapahiProfessor, Buck Institute for Aging ResearchDirección de correo verificada de buckinstitute.org
