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Poncho Meisenheimer
Poncho Meisenheimer
Promega Corporation & Usona Institute
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Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate
MP Hall, J Unch, BF Binkowski, MP Valley, BL Butler, MG Wood, P Otto, ...
ACS chemical biology 7 (11), 1848-1857, 2012
14852012
Quantitative, wide-spectrum kinase profiling in live cells for assessing the effect of cellular ATP on target engagement
JD Vasta, CR Corona, J Wilkinson, CA Zimprich, JR Hartnett, MR Ingold, ...
Cell chemical biology 25 (2), 206-214. e11, 2018
2122018
Bioluminescent, nonlytic, real-time cell viability assay and use in inhibitor screening
SJ Duellman, W Zhou, P Meisenheimer, G Vidugiris, JJ Cali, P Gautam, ...
Assay and drug development technologies 13 (8), 456-465, 2015
1012015
Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use
B Binkowski, LP Encell, M Hall, MB Robers, MR Slater, KV Wood, ...
US Patent 8,669,103, 2014
842014
Novel heterocyclic analogues of firefly luciferin
CC Woodroofe, PL Meisenheimer, DH Klaubert, Y Kovic, JC Rosenberg, ...
Biochemistry 51 (49), 9807-9813, 2012
792012
Quantifying CDK inhibitor selectivity in live cells
CI Wells, JD Vasta, CR Corona, J Wilkinson, CA Zimprich, MR Ingold, ...
Nature communications 11 (1), 2743, 2020
782020
Synthesis and biological evaluation of tryptamines found in hallucinogenic mushrooms: norbaeocystin, baeocystin, norpsilocin, and aeruginascin
AM Sherwood, AL Halberstadt, AK Klein, JD McCorvy, KW Kaylo, ...
Journal of natural products 83 (2), 461-467, 2020
732020
Imidazo [1, 2-α] pyrazine derivatives
DH Klaubert, P Meisenheimer, J Unch
US Patent 8,809,529, 2014
682014
Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate. ACS Chem Biol 7: 1848–1857
MP Hall, J Unch, BF Binkowski, MP Valley, BL Butler, MG Wood, P Otto, ...
682012
N-Alkylated 6′-aminoluciferins are bioluminescent substrates for Ultra-Glo and QuantiLum luciferase: new potential scaffolds for bioluminescent assays
CC Woodroofe, JW Shultz, MG Wood, J Osterman, JJ Cali, WJ Daily, ...
Biochemistry 47 (39), 10383-10393, 2008
682008
Mechanistic studies of the 5-iodouracil chromophore relevant to its use in nucleoprotein photo-cross-linking
CL Norris, PL Meisenheimer, TH Koch
Journal of the American Chemical Society 118 (24), 5796-5803, 1996
631996
Luminogenic and fluorogenic compounds and methods to detect molecules or conditions
JJ Cali, W Daily, E Hawkins, D Klaubert, J Liu, P Meisenheimer, M Scurria, ...
US Patent 7,951,550, 2011
572011
High yield photocrosslinking of a 5-iodocytidine (IC) substituted RNA to its associated protein
KM Meisenheimer, PL Meisenheimer, MC Willis, TH Koch
Nucleic acids research 24 (5), 981-982, 1996
551996
Improving protein array performance: focus on washing and storage conditions
N Nath, R Hurst, B Hook, P Meisenheimer, KQ Zhao, N Nassif, RF Bulleit, ...
Journal of proteome research 7 (10), 4475-4482, 2008
452008
[7] Nucleoprotein photo-cross-linking using halopyrimidine-substituted RNAs
KM Meisenheimer, PL Meisenheimer, TH Koch
Academic Press 318, 88-104, 2000
412000
Proluciferin acetals as bioluminogenic substrates for cytochrome P450 activity and probes for CYP3A inhibition
PL Meisenheimer, HT Uyeda, D Ma, M Sobol, MG McDougall, C Corona, ...
Drug Metabolism and Disposition 39 (12), 2403-2410, 2011
382011
Direct phosphorylation of psilocin enables optimized cGMP kilogram-scale manufacture of psilocybin
RB Kargbo, A Sherwood, A Walker, NV Cozzi, RE Dagger, J Sable, ...
ACS omega 5 (27), 16959-16966, 2020
362020
Bioluminescent assays for ADME evaluation: dialing in CYP selectivity with luminogenic substrates
JJ Cali, D Ma, MG Wood, PL Meisenheimer, DH Klaubert
Expert Opinion on Drug Metabolism & Toxicology 8 (9), 1115-1130, 2012
352012
Coelenterazine derivatives and methods of using same
DH Klaubert, P Meisenheimer, J Unch, W Zhou
US Patent 9,487,520, 2016
302016
Bioluminescent cell-based NAD (P)/NAD (P) H assays for rapid dinucleotide measurement and inhibitor screening
J Vidugiriene, D Leippe, M Sobol, G Vidugiris, W Zhou, P Meisenheimer, ...
Assay and drug development technologies 12 (9-10), 514-526, 2014
282014
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Artículos 1–20