Brian Kobilka
Brian Kobilka
Verified email at stanford.edu
Title
Cited by
Cited by
Year
High-resolution crystal structure of an engineered human β2-adrenergic G protein–coupled receptor
V Cherezov, DM Rosenbaum, MA Hanson, SGF Rasmussen, FS Thian, ...
science 318 (5854), 1258-1265, 2007
35712007
Crystal structure of the β 2 adrenergic receptor–Gs protein complex
SGF Rasmussen, BT DeVree, Y Zou, AC Kruse, KY Chung, TS Kobilka, ...
Nature 477 (7366), 549-555, 2011
26672011
Crystal structure of the human β 2 adrenergic G-protein-coupled receptor
SGF Rasmussen, HJ Choi, DM Rosenbaum, TS Kobilka, FS Thian, ...
Nature 450 (7168), 383-387, 2007
23012007
The structure and function of G-protein-coupled receptors
DM Rosenbaum, SGF Rasmussen, BK Kobilka
Nature 459 (7245), 356-363, 2009
20442009
Structure of a nanobody-stabilized active state of the β 2 adrenoceptor
SGF Rasmussen, HJ Choi, JJ Fung, E Pardon, P Casarosa, PS Chae, ...
Nature 469 (7329), 175-180, 2011
15842011
GPCR engineering yields high-resolution structural insights into β2-adrenergic receptor function
DM Rosenbaum, V Cherezov, MA Hanson, SGF Rasmussen, FS Thian, ...
science 318 (5854), 1266-1273, 2007
15452007
Cloning of the gene and cDNA for mammalian β-adrenergic receptor and homology with rhodopsin
RAF Dixon, BK Kobilka, DJ Strader, JL Benovic, HG Dohlman, T Frielle, ...
Nature 321 (6065), 75-79, 1986
15211986
Crystal structure of the ΅-opioid receptor bound to a morphinan antagonist
A Manglik, AC Kruse, TS Kobilka, FS Thian, JM Mathiesen, RK Sunahara, ...
Nature 485 (7398), 321-326, 2012
12492012
Functional selectivity and classical concepts of quantitative pharmacology
JD Urban, WP Clarke, M Von Zastrow, DE Nichols, B Kobilka, H Weinstein, ...
Journal of Pharmacology and Experimental Therapeutics 320 (1), 1-13, 2007
11122007
Chimeric alpha 2-, beta 2-adrenergic receptors: delineation of domains involved in effector coupling and ligand binding specificity
BK Kobilka, TS Kobilka, K Daniel, JW Regan, MG Caron, RJ Lefkowitz
Science 240 (4857), 1310-1316, 1988
9491988
Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor
BK Kobilka, H Matsui, TS Kobilka, TL Yang-Feng, U Francke, MG Caron, ...
Science 238 (4827), 650-656, 1987
9161987
cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the …
BK Kobilka, RA Dixon, T Frielle, HG Dohlman, MA Bolanowski, IS Sigal, ...
Proceedings of the National Academy of Sciences 84 (1), 46-50, 1987
8321987
Behavioural and cardiovascular effects of disrupting the angiotensin II type-2 receptor gene in mice
L Hein, GS Barsh, RE Pratt, VJ Dzau, BK Kobilka
Nature 377 (6551), 744-747, 1995
7981995
βAR signaling required for diet-induced thermogenesis and obesity resistance
ES Bachman, H Dhillon, CY Zhang, S Cinti, AC Bianco, BK Kobilka, ...
Science 297 (5582), 843-845, 2002
7952002
Cloning of the cDNA for the human beta 1-adrenergic receptor
T Frielle, S Collins, KW Daniel, MG Caron, RJ Lefkowitz, BK Kobilka
Proceedings of the National Academy of Sciences 84 (22), 7920-7924, 1987
7851987
Structure and function of an irreversible agonist-β 2 adrenoceptor complex
DM Rosenbaum, C Zhang, JA Lyons, R Holl, D Aragao, DH Arlow, ...
Nature 469 (7329), 236-240, 2011
7802011
G protein-coupled receptors II. Mechanism of agonist activation
U Gether, BK Kobilka
Journal of Biological Chemistry 273 (29), 17979-17982, 1998
7781998
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
K Haga, AC Kruse, H Asada, T Yurugi-Kobayashi, M Shiroishi, C Zhang, ...
Nature 482 (7386), 547-551, 2012
7752012
The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT 1A receptor
A Fargin, JR Raymond, MJ Lohse, BK Kobilka, MG Caron, RJ Lefkowitz
Nature 335 (6188), 358-360, 1988
7741988
Conformational complexity of G-protein-coupled receptors
BK Kobilka, X Deupi
Trends in pharmacological sciences 28 (8), 397-406, 2007
7732007
The system can't perform the operation now. Try again later.
Articles 1–20