Advancing biological understanding and therapeutics discovery with small-molecule probes SL Schreiber, JD Kotz, M Li, J Aubé, CP Austin, JC Reed, H Rosen, ... Cell 161 (6), 1252-1265, 2015 | 164 | 2015 |
Evaluation of anti-Zika virus activities of broad-spectrum antivirals and NIH clinical collection compounds using a cell-based, high-throughput screen assay RS Adcock, YK Chu, JE Golden, DH Chung Antiviral research 138, 47-56, 2017 | 123 | 2017 |
Dynein-dependent transport of the hantaan virus nucleocapsid protein to the endoplasmic reticulum-Golgi intermediate compartment HN Ramanathan, DH Chung, SJ Plane, E Sztul, Y Chu, MC Guttieri, ... Journal of virology 81 (16), 8634-8647, 2007 | 110 | 2007 |
Synthesis of 1-β-d-ribofuranosyl-3-ethynyl-[1, 2, 4] triazole and its in vitro and in vivo efficacy against Hantavirus DH Chung, SC Kumarapperuma, Y Sun, Q Li, YK Chu, JB Arterburn, ... Antiviral research 79 (1), 19-27, 2008 | 72 | 2008 |
Ribavirin reveals a lethal threshold of allowable mutation frequency for Hantaan virus DH Chung, Y Sun, WB Parker, JB Arterburn, A Bartolucci, CB Jonsson Journal of virology 81 (21), 11722-11729, 2007 | 66 | 2007 |
Rapid sequencing of multiple RNA viruses in their native form T Wongsurawat, P Jenjaroenpun, MK Taylor, J Lee, AL Tolardo, ... Frontiers in microbiology 10, 260, 2019 | 60 | 2019 |
Activity of ribavirin against Hantaan virus correlates with production of ribavirin-5′-triphosphate, not with inhibition of IMP dehydrogenase Y Sun, DH Chung, YK Chu, CB Jonsson, WB Parker Antimicrobial agents and chemotherapy 51 (1), 84-88, 2007 | 60 | 2007 |
High-throughput screening of a 100,000-compound library for inhibitors of influenza A virus (H3N2) WE Severson, M McDowell, S Ananthan, DH Chung, L Rasmussen, ... Journal of biomolecular screening 13 (9), 879-887, 2008 | 57 | 2008 |
Discovery of a broad-spectrum antiviral compound that inhibits pyrimidine biosynthesis and establishes a type 1 interferon-independent antiviral state DH Chung, JE Golden, RS Adcock, CE Schroeder, YK Chu, JB Sotsky, ... Antimicrobial agents and chemotherapy 60 (8), 4552-4562, 2016 | 55 | 2016 |
Zika virus infects pericytes in the choroid plexus and enters the central nervous system through the blood-cerebrospinal fluid barrier J Kim, B Alejandro, M Hetman, EM Hattab, J Joiner, H Schroten, ... PLoS pathogens 16 (5), e1008204, 2020 | 54 | 2020 |
Ribosomal stress and Tp53-mediated neuronal apoptosis in response to capsid protein of the Zika virus LP Slomnicki, DH Chung, A Parker, T Hermann, NL Boyd, M Hetman Scientific reports 7 (1), 16652, 2017 | 54 | 2017 |
Development of (E)-2-((1,4-Dimethylpiperazin-2-ylidene)amino)-5-nitro-N-phenylbenzamide, ML336: Novel 2-Amidinophenylbenzamides as Potent Inhibitors of … CE Schroeder, T Yao, J Sotsky, RA Smith, S Roy, YK Chu, H Guo, ... Journal of Medicinal Chemistry 57 (20), 8608-8621, 2014 | 50 | 2014 |
Discovery of a novel compound with anti-Venezuelan equine encephalitis virus activity that targets the nonstructural protein 2 DH Chung, CB Jonsson, NA Tower, YK Chu, E Sahin, JE Golden, ... PLoS pathogens 10 (6), e1004213, 2014 | 47 | 2014 |
Potent antiviral activity against HSV-1 and SARS-CoV-2 by antimicrobial peptoids G Diamond, N Molchanova, C Herlan, JA Fortkort, JS Lin, E Figgins, ... Pharmaceuticals 14 (4), 304, 2021 | 40 | 2021 |
Variant analysis of 1,040 SARS-CoV-2 genomes EC Rouchka, JH Chariker, D Chung PLoS One 15 (11), e0241535, 2020 | 38 | 2020 |
Yersinia pestis Targets the Host Endosome Recycling Pathway during the Biogenesis of the Yersinia-Containing Vacuole To Avoid Killing by Macrophages MG Connor, AR Pulsifer, D Chung, EC Rouchka, BK Ceresa, MB Lawrenz MBio 9 (1), 10.1128/mbio. 01800-17, 2018 | 34 | 2018 |
Inflammasome-Independent Leukotriene B4 Production Drives Crystalline Silica–Induced Sterile Inflammation B Hegde, SR Bodduluri, SR Satpathy, RS Alghsham, VR Jala, SM Uriarte, ... The Journal of Immunology 200 (10), 3556-3567, 2018 | 29 | 2018 |
Optimization of potent and selective quinazolinediones: inhibitors of respiratory syncytial virus that block RNA-dependent RNA-polymerase complex activity DS Matharu, DP Flaherty, DS Simpson, CE Schroeder, D Chung, D Yan, ... Journal of medicinal chemistry 57 (24), 10314-10328, 2014 | 29 | 2014 |
The murine model for Hantaan virus-induced lethal disease shows two distinct paths in viral evolutionary trajectory with and without ribavirin treatment DH Chung, Å Västermark, JV Camp, R McAllister, SK Remold, YK Chu, ... Journal of virology 87 (20), 10997-11007, 2013 | 24 | 2013 |
A cell based high-throughput screening approach for the discovery of new inhibitors of respiratory syncytial virus DH Chung, BP Moore, DS Matharu, JE Golden, C Maddox, L Rasmussen, ... Virology journal 10, 1-12, 2013 | 22 | 2013 |