Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients R Dutta, J McDonough, X Yin, J Peterson, A Chang, T Torres, T Gudz, ... Annals of neurology 59 (3), 478-489, 2006 | 964 | 2006 |
Analysis of the mitochondrial proteome in multiple sclerosis cortex L Broadwater, A Pandit, R Clements, S Azzam, J Vadnal, M Sulak, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1812 (5), 630-641, 2011 | 127 | 2011 |
Activation of the ciliary neurotrophic factor (CNTF) signalling pathway in cortical neurons of multiple sclerosis patients R Dutta, J McDonough, A Chang, L Swamy, A Siu, GJ Kidd, R Rudick, ... Brain 130 (10), 2566-2576, 2007 | 103 | 2007 |
Distribution of parvalbumin and calretinin immunoreactive interneurons in motor cortex from multiple sclerosis post-mortem tissue RJ Clements, J McDonough, EJ Freeman Experimental Brain Research 187, 459-465, 2008 | 85 | 2008 |
Liquid crystal elastomer foams with elastic properties specifically engineered as biodegradable brain tissue scaffolds ME Prévôt, H Andro, SLM Alexander, S Ustunel, C Zhu, Z Nikolov, ... Soft Matter 14 (3), 354-360, 2018 | 68 | 2018 |
Biocompatible, biodegradable and porous liquid crystal elastomer scaffolds for spatial cell cultures A Sharma, A Neshat, CJ Mahnen, AD Nielsen, J Snyder, TL Stankovich, ... Macromolecular bioscience 15 (2), 200-214, 2015 | 68 | 2015 |
Neuronal hemoglobin expression and its relevance to multiple sclerosis neuropathology N Brown, K Alkhayer, R Clements, N Singhal, R Gregory, S Azzam, S Li, ... Journal of molecular neuroscience 59, 1-17, 2016 | 64 | 2016 |
Impaired regulation of electron transport chain subunit genes by nuclear respiratory factor 2 in multiple sclerosis A Pandit, J Vadnal, S Houston, E Freeman, J McDonough Journal of the neurological sciences 279 (1-2), 14-20, 2009 | 64 | 2009 |
Characterization of an acetylcholine receptor alpha 3 gene promoter and its activation by the POU domain factor SCIP/Tst-1. X Yang, J McDonough, D Fyodorov, M Morris, F Wang, ES Deneris Journal of Biological Chemistry 269 (14), 10252-10264, 1994 | 63 | 1994 |
Liquid crystal elastomer microspheres as three-dimensional cell scaffolds supporting the attachment and proliferation of myoblasts T Bera, EJ Freeman, JA McDonough, RJ Clements, A Aladlaan, DW Miller, ... ACS Applied Materials & Interfaces 7 (26), 14528-14535, 2015 | 62 | 2015 |
Changes in methionine metabolism and histone H3 trimethylation are linked to mitochondrial defects in multiple sclerosis NK Singhal, S Li, E Arning, K Alkhayer, R Clements, Z Sarcyk, ... Journal of Neuroscience 35 (45), 15170-15186, 2015 | 61 | 2015 |
Ablating N‐acetylaspartate prevents leukodystrophy in a C anavan disease model F Guo, P Bannerman, E Mills Ko, L Miers, J Xu, T Burns, S Li, E Freeman, ... Annals of neurology 77 (5), 884-888, 2015 | 57 | 2015 |
β43′: an enhancer displaying neural-restricted activity is located in the 3′-untranslated exon of the rat nicotinic acetylcholine receptor β4 gene J McDonough, E Deneris Journal of Neuroscience 17 (7), 2273-2283, 1997 | 48 | 1997 |
Decreased NAA in gray matter is correlated with decreased availability of acetate in white matter in postmortem multiple sclerosis cortex S Li, R Clements, M Sulak, R Gregory, E Freeman, J McDonough Neurochemical research 38, 2385-2396, 2013 | 47 | 2013 |
The neuronal metabolite NAA regulates histone H3 methylation in oligodendrocytes and myelin lipid composition NK Singhal, H Huang, S Li, R Clements, J Gadd, A Daniels, EE Kooijman, ... Experimental brain research 235, 279-292, 2017 | 43 | 2017 |
Dysmyelinated lower motor neurons retract and regenerate dysfunctional synaptic terminals X Yin, GJ Kidd, EP Pioro, J McDonough, R Dutta, ML Feltri, L Wrabetz, ... Journal of Neuroscience 24 (15), 3890-3898, 2004 | 34 | 2004 |
Erythropoietin upregulates brain hemoglobin expression and supports neuronal mitochondrial activity NK Singhal, K Alkhayer, J Shelestak, R Clements, E Freeman, ... Molecular neurobiology 55, 8051-8058, 2018 | 33 | 2018 |
Dysregulation of methionine metabolism in multiple sclerosis NK Singhal, E Freeman, E Arning, B Wasek, R Clements, C Sheppard, ... Neurochemistry international 112, 1-4, 2018 | 32 | 2018 |
Effects of structural variations on the cellular response and mechanical properties of biocompatible, biodegradable, and porous smectic liquid crystal elastomers A Sharma, T Mori, CJ Mahnen, HR Everson, MT Leslie, A Nielsen, ... Macromolecular bioscience 17 (2), 1600278, 2017 | 32 | 2017 |
Elements between the protein‐coding regions of the adjacent β4 and α3 acetylcholine receptor genes direct neuron‐specific expression in the central nervous system X Yang, F Yang, D Fyodorov, F Wang, J McDonough, K Herrup, E Deneris Journal of neurobiology 32 (3), 311-324, 1997 | 31 | 1997 |