David H. Spencer
David H. Spencer
Assistant Professor, Division of Oncology, Department of Medicine, Washington University
Verified email at wustl.edu
Title
Cited by
Cited by
Year
Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen
CK Stover, XQ Pham, AL Erwin, SD Mizoguchi, P Warrener, MJ Hickey, ...
Nature 406 (6799), 959-964, 2000
46272000
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
Cancer Genome Atlas Research Network
New England Journal of Medicine 368 (22), 2059-2074, 2013
28852013
Comprehensive transposon mutant library of Pseudomonas aeruginosa
MA Jacobs, A Alwood, I Thaipisuttikul, D Spencer, E Haugen, S Ernst, ...
Proceedings of the National Academy of Sciences 100 (24), 14339-14344, 2003
10822003
Functional heterogeneity of genetically defined subclones in acute myeloid leukemia
JM Klco, DH Spencer, CA Miller, M Griffith, TL Lamprecht, M O’Laughlin, ...
Cancer cell 25 (3), 379-392, 2014
3242014
Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients
DA D'Argenio, M Wu, LR Hoffman, HD Kulasekara, E Déziel, EE Smith, ...
Molecular microbiology 64 (2), 512-533, 2007
3212007
The R882H DNMT3A mutation associated with AML dominantly inhibits wild-type DNMT3A by blocking its ability to form active tetramers
DA Russler-Germain, DH Spencer, MA Young, TL Lamprecht, CA Miller, ...
Cancer cell 25 (4), 442-454, 2014
2962014
Association between mutation clearance after induction therapy and outcomes in acute myeloid leukemia
JM Klco, CA Miller, M Griffith, A Petti, DH Spencer, S Ketkar-Kulkarni, ...
Jama 314 (8), 811-822, 2015
2702015
CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer
M Griffith, NC Spies, K Krysiak, JF McMichael, AC Coffman, AM Danos, ...
Nature genetics 49 (2), 170-174, 2017
2672017
Whole-genome sequence variation among multiple isolates of Pseudomonas aeruginosa
DH Spencer, A Kas, EE Smith, CK Raymond, EH Sims, M Hastings, ...
Journal of bacteriology 185 (4), 1316-1325, 2003
2402003
Evidence for diversifying selection at the pyoverdine locus of Pseudomonas aeruginosa
EE Smith, EH Sims, DH Spencer, R Kaul, MV Olson
Journal of bacteriology 187 (6), 2138-2147, 2005
1762005
Genetic variation at the O-antigen biosynthetic locus in Pseudomonas aeruginosa
CK Raymond, EH Sims, A Kas, DH Spencer, TV Kutyavin, RG Ivey, ...
Journal of bacteriology 184 (13), 3614-3622, 2002
1722002
Validation of a next-generation sequencing assay for clinical molecular oncology
CE Cottrell, H Al-Kateb, AJ Bredemeyer, EJ Duncavage, DH Spencer, ...
The Journal of molecular diagnostics 16 (1), 89-105, 2014
1632014
Clinical next‐generation sequencing in patients with non–small cell lung cancer
IS Hagemann, S Devarakonda, CM Lockwood, DH Spencer, K Guebert, ...
Cancer 121 (4), 631-639, 2015
1582015
Comparison of clinical targeted next-generation sequence data from formalin-fixed and fresh-frozen tissue specimens
DH Spencer, JK Sehn, HJ Abel, MA Watson, JD Pfeifer, EJ Duncavage
The Journal of molecular diagnostics 15 (5), 623-633, 2013
1472013
Genomic impact of transient low-dose decitabine treatment on primary AML cells
JM Klco, DH Spencer, TL Lamprecht, SM Sarkaria, T Wylie, V Magrini, ...
Blood 121 (9), 1633-1643, 2013
1342013
CpG island hypermethylation mediated by DNMT3A is a consequence of AML progression
DH Spencer, DA Russler-Germain, S Ketkar, NM Helton, TL Lamprecht, ...
Cell 168 (5), 801-816. e13, 2017
1172017
Genome mosaicism is conserved but not unique in Pseudomonas aeruginosa isolates from the airways of young children with cystic fibrosis
RK Ernst, DA D′ Argenio, JK Ichikawa, MG Bangera, S Selgrade, ...
Environmental microbiology 5 (12), 1341-1349, 2003
1162003
Performance of common analysis methods for detecting low-frequency single nucleotide variants in targeted next-generation sequence data
DH Spencer, M Tyagi, F Vallania, AJ Bredemeyer, JD Pfeifer, RD Mitra, ...
The Journal of Molecular Diagnostics 16 (1), 75-88, 2014
1142014
Detection of FLT3 internal tandem duplication in targeted, short-read-length, next-generation sequencing data
DH Spencer, HJ Abel, CM Lockwood, JE Payton, P Szankasi, TW Kelley, ...
The Journal of molecular diagnostics 15 (1), 81-93, 2013
1072013
Epigenomic analysis of the HOX gene loci reveals mechanisms that may control canonical expression patterns in AML and normal hematopoietic cells
DH Spencer, MA Young, TL Lamprecht, NM Helton, R Fulton, ...
Leukemia 29 (6), 1279-1289, 2015
762015
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