| Human factor H-related protein 5 has cofactor activity, inhibits C3 convertase activity, binds heparin and C-reactive protein, and associates with lipoprotein JL McRae, TG Duthy, KM Griggs, RJ Ormsby, PJ Cowan, BA Cromer, ... The Journal of Immunology 174 (10), 6250-6256, 2005 | 212 | 2005 |
| A common site within factor H SCR 7 responsible for binding heparin, C‐reactive protein and streptococcal M protein E Giannakis, TS Jokiranta, DA Male, S Ranganathan, RJ Ormsby, ... European journal of immunology 33 (4), 962-969, 2003 | 209 | 2003 |
| Binding of complement factor H to endothelial cells is mediated by the carboxy-terminal glycosaminoglycan binding site TS Jokiranta, ZZ Cheng, H Seeberger, M Jòzsi, S Heinen, M Noris, ... The American journal of pathology 167 (4), 1173-1181, 2005 | 152 | 2005 |
| The human complement regulator factor H binds pneumococcal surface protein PspC via short consensus repeats 13 to 15 TG Duthy, RJ Ormsby, E Giannakis, AD Ogunniyi, UH Stroeher, JC Paton, ... Infection and immunity 70 (10), 5604-5611, 2002 | 119 | 2002 |
| Functional and structural implications of the complement factor H Y402H polymorphism associated with age-related macular degeneration RJ Ormsby, S Ranganathan, JC Tong, KM Griggs, DP Dimasi, AW Hewitt, ... Investigative ophthalmology & visual science 49 (5), 1763-1770, 2008 | 99 | 2008 |
| Identification of the streptococcal M protein binding site on membrane cofactor protein (CD46) E Giannakis, TS Jokiranta, RJ Ormsby, TG Duthy, DA Male, ... The Journal of Immunology 168 (9), 4585-4592, 2002 | 88 | 2002 |
| Localization of the third heparin-binding site in the human complement regulator factor H1 RJ Ormsby, TS Jokiranta, TG Duthy, KM Griggs, TA Sadlon, E Giannakis, ... Molecular immunology 43 (10), 1624-1632, 2006 | 87 | 2006 |
| Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes DA Male, RJ Ormsby, S Ranganathan, E Giannakis, DL Gordon Molecular immunology 37 (1-2), 41-52, 2000 | 80 | 2000 |
| Multiple ligand binding sites on domain seven of human complement factor H E Giannakis, DA Male, RJ Ormsby, C Mold, TS Jokiranta, S Ranganathan, ... International immunopharmacology 1 (3), 433-443, 2001 | 71 | 2001 |
| The regulatory SCR-1/5 and cell surface-binding SCR-16/20 fragments of factor H reveal partially folded-back solution structures and different self-associative properties AI Okemefuna, HE Gilbert, KM Griggs, RJ Ormsby, DL Gordon, SJ Perkins Journal of molecular biology 375 (1), 80-101, 2008 | 61 | 2008 |
| Protection from radiation-induced apoptosis by the radioprotector amifostine (WR-2721) is radiation dose dependent RJ Ormsby, MD Lawrence, BJ Blyth, K Bexis, E Bezak, JS Murley, ... Cell biology and toxicology 30, 55-66, 2014 | 43 | 2014 |
| GD2-targeting CAR-T cells enhanced by transgenic IL-15 expression are an effective and clinically feasible therapy for glioblastoma T Gargett, LM Ebert, NTH Truong, PM Kollis, K Sedivakova, W Yu, ... Journal for Immunotherapy of Cancer 10 (9), 2022 | 41 | 2022 |
| Sensitive quantitative analysis of murine LINE1 DNA methylation using high resolution melt analysis M Newman, BJ Blyth, DJ Hussey, D Jardine, PJ Sykes, RJ Ormsby Epigenetics 7 (1), 92-105, 2012 | 40 | 2012 |
| Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy LM Ebert, W Yu, T Gargett, J Toubia, PM Kollis, MN Tea, BW Ebert, ... Clinical & Translational Immunology 9 (10), e1191, 2020 | 37 | 2020 |
| Parthenolide Selectively Sensitizes Prostate Tumor Tissue to Radiotherapy while Protecting Healthy Tissues In Vivo KL Morel, RJ Ormsby, E Bezak, CJ Sweeney, PJ Sykes Radiation research 187 (5), 501-512, 2017 | 37 | 2017 |
| 3D-printed microplate inserts for long term high-resolution imaging of live brain organoids M Oksdath Mansilla, C Salazar-Hernandez, SL Perrin, KG Scheer, ... BMC biomedical engineering 3, 1-14, 2021 | 31 | 2021 |
| The combination of metformin and valproic acid induces synergistic apoptosis in the presence of p53 and androgen signaling in prostate cancer LNK Tran, G Kichenadasse, LM Butler, MM Centenera, KL Morel, ... Molecular Cancer Therapeutics 16 (12), 2689-2700, 2017 | 30 | 2017 |
| A drug screening pipeline using 2D and 3D patient-derived in vitro models for pre-clinical analysis of therapy response in glioblastoma S Lenin, E Ponthier, KG Scheer, ECF Yeo, MN Tea, LM Ebert, ... International Journal of Molecular Sciences 22 (9), 4322, 2021 | 29 | 2021 |
| The methylation of DNA repeat elements is sex-dependent and temporally different in response to X radiation in radiosensitive and radioresistant mouse strains MR Newman, PJ Sykes, BJ Blyth, E Bezak, MD Lawrence, KL Morel, ... Radiation research 181 (1), 65-75, 2014 | 28 | 2014 |
| A deep convolutional neural network for segmentation of whole-slide pathology images identifies novel tumour cell-perivascular niche interactions that are associated with poor … A Zadeh Shirazi, MD McDonnell, E Fornaciari, NS Bagherian, KG Scheer, ... British Journal of Cancer 125 (3), 337-350, 2021 | 26 | 2021 |
