Active RNA polymerases are localized within discrete transcription ‘factories’ in human nuclei FJ Iborra, A Pombo, DA Jackson, PR Cook Journal of cell science 109 (6), 1427-1436, 1996 | 570 | 1996 |
Coupled transcription and translation within nuclei of mammalian cells FJ Iborra, DA Jackson, PR Cook Science 293 (5532), 1139-1142, 2001 | 488 | 2001 |
The functional organization of mitochondrial genomes in human cells FJ Iborra, H Kimura, PR Cook BMC biology 2, 1-14, 2004 | 437 | 2004 |
MicroRNA-210 regulates mitochondrial free radical response to hypoxia and krebs cycle in cancer cells by targeting iron sulfur cluster protein ISCU E Favaro, A Ramachandran, R McCormick, H Gee, C Blancher, M Crosby, ... PloS one 5 (4), e10345, 2010 | 371 | 2010 |
Numbers and organization of RNA polymerases, nascent transcripts, and transcription units in HeLa nuclei DA Jackson, FJ Iborra, EMM Manders, PR Cook Molecular biology of the cell 9 (6), 1523-1536, 1998 | 367 | 1998 |
Cellular differentiation hierarchies in normal and culture-adapted human embryonic stem cells T Enver, S Soneji, C Joshi, J Brown, F Iborra, T Orntoft, T Thykjaer, ... Human molecular genetics 14 (21), 3129-3140, 2005 | 359 | 2005 |
Association between active genes occurs at nuclear speckles and is modulated by chromatin environment JM Brown, J Green, RP das Neves, HAC Wallace, AJH Smith, J Hughes, ... The Journal of cell biology 182 (6), 1083-1097, 2008 | 321 | 2008 |
Coregulated human globin genes are frequently in spatial proximity when active JM Brown, J Leach, JE Reittie, A Atzberger, J Lee-Prudhoe, WG Wood, ... The Journal of cell biology 172 (2), 177-187, 2006 | 247 | 2006 |
The balance sheet for transcription: an analysis of nuclear RNA metabolism in mammalian cells DA Jackson, ANA Pombo, F Iborra The FASEB Journal 14 (2), 242-254, 2000 | 200 | 2000 |
ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis AH Schuh, AJ Tipping, AJ Clark, I Hamlett, B Guyot, FJ Iborra, ... Molecular and cellular biology 25 (23), 10235-10250, 2005 | 182 | 2005 |
Connecting variability in global transcription rate to mitochondrial variability RP Das Neves, NS Jones, L Andreu, R Gupta, T Enver, FJ Iborra PLoS biology 8 (12), e1000560, 2010 | 165 | 2010 |
Mitochondrial variability as a source of extrinsic cellular noise IG Johnston, B Gaal, RP Neves, T Enver, FJ Iborra, NS Jones PLoS computational biology 8 (3), e1002416, 2012 | 156 | 2012 |
Mitochondrial levels determine variability in cell death by modulating apoptotic gene expression S Márquez-Jurado, J Díaz-Colunga, RP das Neves, A Martinez-Lorente, ... Nature communications 9 (1), 389, 2018 | 151 | 2018 |
NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells R Gupta, D Hong, F Iborra, S Sarno, T Enver Science 316 (5824), 590-593, 2007 | 139 | 2007 |
Asymmetry of DNA replication fork progression in Werner's syndrome AM Rodríguez‐López, DA Jackson, F Iborra, LS Cox Aging cell 1 (1), 30-39, 2002 | 138 | 2002 |
MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen-and stress-activated kinase 1/2 MH Dyson, S Thomson, M Inagaki, H Goto, SJ Arthur, K Nightingale, ... Journal of cell science 118 (10), 2247-2259, 2005 | 134 | 2005 |
Global variability in gene expression and alternative splicing is modulated by mitochondrial content R Guantes, A Rastrojo, R Neves, A Lima, B Aguado, FJ Iborra Genome research 25 (5), 633-644, 2015 | 125 | 2015 |
Cord blood-derived CD34+ hematopoietic cells with low mitochondrial mass are enriched in hematopoietic repopulating stem cell function D Romero-Moya, C Bueno, R Montes, O Navarro-Montero, FJ Iborra, ... Haematologica 98 (7), 1022, 2013 | 98 | 2013 |
GATA1-mediated megakaryocyte differentiation and growth control can be uncoupled and mapped to different domains in GATA1 C Kuhl, A Atzberger, F Iborra, B Nieswandt, C Porcher, P Vyas Molecular and cellular biology 25 (19), 8592-8606, 2005 | 97 | 2005 |
A novel histone exchange factor, protein phosphatase 2Cγ, mediates the exchange and dephosphorylation of H2A–H2B H Kimura, N Takizawa, E Allemand, T Hori, FJ Iborra, N Nozaki, M Muraki, ... The Journal of cell biology 175 (3), 389-400, 2006 | 95 | 2006 |