Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers JA Engelman, L Chen, X Tan, K Crosby, AR Guimaraes, R Upadhyay, ... Nature medicine 14 (12), 1351-1356, 2008 | 1554 | 2008 |
Bioorthogonal turn-on probes for imaging small molecules inside living cells NK Devaraj, S Hilderbrand, R Upadhyay, R Mazitschek, R Weissleder Angewandte Chemie (International ed. in English) 49 (16), 2869, 2010 | 469 | 2010 |
Fast and sensitive pretargeted labeling of cancer cells via tetrazine/trans-cyclooctene cycloaddition NK Devaraj, R Upadhyay, JB Haun, SA Hilderbrand, R Weissleder Angewandte Chemie (International ed. in English) 48 (38), 7013, 2009 | 444 | 2009 |
Endoscopic photoconversion reveals unexpectedly broad leukocyte trafficking to and from the gut AM Morton, E Sefik, R Upadhyay, R Weissleder, C Benoist, D Mathis Proceedings of the National Academy of Sciences 111 (18), 6696-6701, 2014 | 177 | 2014 |
Accurate measurement of pancreatic islet β-cell mass using a second-generation fluorescent exendin-4 analog T Reiner, G Thurber, J Gaglia, C Vinegoni, CW Liew, R Upadhyay, ... Proceedings of the National Academy of Sciences 108 (31), 12815-12820, 2011 | 131 | 2011 |
Regression of drug-resistant lung cancer by the combination of rosiglitazone and carboplatin GD Girnun, L Chen, J Silvaggi, R Drapkin, LR Chirieac, RF Padera, ... Clinical cancer research 14 (20), 6478-6486, 2008 | 103 | 2008 |
Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation V Cortez-Retamozo, FK Swirski, P Waterman, H Yuan, JL Figueiredo, ... The Journal of clinical investigation 118 (12), 4058-4066, 2008 | 86 | 2008 |
Improved detection of ovarian cancer metastases by intraoperative quantitative fluorescence protease imaging in a pre-clinical model RA Sheth, R Upadhyay, L Stangenberg, R Sheth, R Weissleder, ... Gynecologic oncology 112 (3), 616-622, 2009 | 83 | 2009 |
Bone marrow stromal cell transplants prevent experimental enterocolitis and require host CD11b+ splenocytes B Parekkadan, R Upadhyay, J Dunham, Y Iwamoto, E Mizoguchi, ... Gastroenterology 140 (3), 966-975. e4, 2011 | 77 | 2011 |
Systems and methods for generating fluorescent light images U Mahmood, R Weissleder, RA Sheth, R Upadhyay US Patent 8,078,265, 2011 | 76 | 2011 |
Human Breast Cancer Tumor Models: Molecular Imaging of Drug Susceptibility and Dosing during HER2/neu-targeted Therapy MS Gee, R Upadhyay, H Bergquist, H Alencar, F Reynolds, M Maricevich, ... Radiology 248 (3), 925-935, 2008 | 75 | 2008 |
Efficacy and safety of COVID-19 convalescent plasma in hospitalized patients: a randomized clinical trial MB Ortigoza, H Yoon, KS Goldfeld, AB Troxel, JP Daily, Y Wu, Y Li, D Wu, ... JAMA internal medicine 182 (2), 115-126, 2022 | 73 | 2022 |
Efficient 18F‐Labeling of Synthetic Exendin‐4 Analogues for Imaging Beta Cells EJ Keliher, T Reiner, GM Thurber, R Upadhyay, R Weissleder ChemistryOpen 1 (4), 177-183, 2012 | 56 | 2012 |
Quantitative Real-time Catheter-based Fluorescence Molecular Imaging in Mice1 R Upadhyay, RA Sheth, R Weissleder, U Mahmood Radiology 245 (2), 523-531, 2007 | 51 | 2007 |
N-Cadherin and Keratinocyte Growth Factor Receptor Mediate the Functional Interplay between Ki-RASG12V and p53V143A in Promoting Pancreatic Cell … TB Deramaudt, M Takaoka, R Upadhyay, MJ Bowser, J Porter, A Lee, ... Molecular and cellular biology 26 (11), 4185-4200, 2006 | 42 | 2006 |
Systems-level modeling of cancer-fibroblast interaction RC Wadlow, BS Wittner, SA Finley, H Bergquist, R Upadhyay, S Finn, ... PloS one 4 (9), e6888, 2009 | 40 | 2009 |
Improved in Vivo Whole-Animal Detection Limits of Green Fluorescent Protein–Expressing Tumor Lines by Spectral Fluorescence Imaging JM Tam, R Upadhyay, MJ Pittet, R Weissleder, U Mahmood Molecular imaging 6 (4), 7290.2007. 00023, 2007 | 40 | 2007 |
Systems and methods for generating fluorescent light images U Mahmood, R Weissleder, RA Sheth, R Upadhyay US Patent 8,423,127, 2013 | 26 | 2013 |
Real-time multichannel imaging framework for endoscopy, catheters, and fixed geometry intraoperative systems RA Sheth, R Upadhyay, R Weissleder, U Mahmood Molecular imaging 6 (3), 7290.2007. 00012, 2007 | 23 | 2007 |
Multiparameter noninvasive assessment of treatment susceptibility, drug target inhibition and tumor response guides cancer treatment MS Gee, R Upadhyay, H Bergquist, R Weissleder, L Josephson, ... International journal of cancer 121 (11), 2492-2500, 2007 | 15 | 2007 |