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James Fitzpatrick
James Fitzpatrick
Global Head, Scientific Operations pRED 360 Labs, Roche
Dirección de correo verificada de roche.com
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Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy
DF Egan, DB Shackelford, MM Mihaylova, S Gelino, RA Kohnz, W Mair, ...
Science 331 (6016), 456-461, 2011
26672011
Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet
M Hatori, C Vollmers, A Zarrinpar, L DiTacchio, EA Bushong, S Gill, ...
Cell metabolism 15 (6), 848-860, 2012
19322012
Sentinel lymph node imaging using quantum dots in mouse tumor models
B Ballou, LA Ernst, S Andreko, T Harper, JAJ Fitzpatrick, AS Waggoner, ...
Bioconjugate chemistry 18 (2), 389-396, 2007
4332007
Fluorogen-activating single-chain antibodies for imaging cell surface proteins
C Szent-Gyorgyi, BF Schmidt, Y Creeger, GW Fisher, KL Zakel, S Adler, ...
Nature biotechnology 26 (2), 235-240, 2008
4152008
Functional characterization of the dural sinuses as a neuroimmune interface
J Rustenhoven, A Drieu, T Mamuladze, KA de Lima, T Dykstra, M Wall, ...
Cell 184 (4), 1000-1016. e27, 2021
3632021
Heterogeneity of meningeal B cells reveals a lymphopoietic niche at the CNS borders
S Brioschi, WL Wang, V Peng, M Wang, I Shchukina, ZJ Greenberg, ...
Science 373 (6553), eabf9277, 2021
2482021
Ubiquitin facilitates a quality-control pathway that removes damaged chloroplasts
JD Woodson, MS Joens, AB Sinson, J Gilkerson, PA Salomé, D Weigel, ...
Science 350 (6259), 450-454, 2015
1922015
A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest
MT Hayashi, AJ Cesare, JAJ Fitzpatrick, E Lazzerini-Denchi, J Karlseder
Nature structural & molecular biology 19 (4), 387-394, 2012
1872012
Long-term persistence and spectral blue shifting of quantum dots in vivo
JAJ Fitzpatrick, SK Andreko, LA Ernst, AS Waggoner, B Ballou, ...
Nano Letters 9 (7), 2736-2741, 2009
1822009
Helium Ion Microscopy (HIM) for the imaging of biological samples at sub-nanometer resolution
MS Joens, C Huynh, JM Kasuboski, D Ferranti, YJ Sigal, F Zeitvogel, ...
Scientific reports 3 (1), 3514, 2013
1742013
SARS-CoV-2 infects human engineered heart tissues and models COVID-19 myocarditis
AL Bailey, O Dmytrenko, L Greenberg, AL Bredemeyer, P Ma, J Liu, ...
Basic to Translational Science 6 (4), 331-345, 2021
1632021
Cryo-EM structure of a neuronal functional amyloid implicated in memory persistence in Drosophila
R Hervas, MJ Rau, Y Park, W Zhang, AG Murzin, JAJ Fitzpatrick, ...
Science 367 (6483), 1230-1234, 2020
1572020
Human telomeres are tethered to the nuclear envelope during postmitotic nuclear assembly
L Crabbe, AJ Cesare, JM Kasuboski, JAJ Fitzpatrick, J Karlseder
Cell reports 2 (6), 1521-1529, 2012
1372012
Modern laser scanning confocal microscopy
PO Bayguinov, DM Oakley, CC Shih, DJ Geanon, MS Joens, ...
Current protocols in cytometry 85 (1), e39, 2018
1342018
Cholera toxin B conjugated quantum dots for live cell labeling
SK Chakraborty, JAJ Fitzpatrick, JA Phillippi, S Andreko, AS Waggoner, ...
Nano Letters 7 (9), 2618-2626, 2007
1322007
In vitro myelin formation using embryonic stem cells
BE Kerman, HJ Kim, K Padmanabhan, A Mei, S Georges, MS Joens, ...
Development 142 (12), 2213-2225, 2015
1052015
Catheterization alters bladder ecology to potentiate Staphylococcus aureus infection of the urinary tract
JN Walker, AL Flores-Mireles, CL Pinkner, HL Schreiber IV, MS Joens, ...
Proceedings of the National Academy of Sciences 114 (41), E8721-E8730, 2017
1042017
Cryo-EM structures of the ATP release channel pannexin 1
Z Deng, Z He, G Maksaev, RM Bitter, M Rau, JAJ Fitzpatrick, P Yuan
Nature structural & molecular biology 27 (4), 373-381, 2020
1032020
Characterization of a Mycobacterium tuberculosis nanocompartment and its potential cargo proteins
H Contreras, MS Joens, LM McMath, VP Le, MV Tullius, JM Kimmey, ...
Journal of Biological Chemistry 289 (26), 18279-18289, 2014
1032014
Resident cardiac macrophages mediate adaptive myocardial remodeling
NR Wong, J Mohan, BJ Kopecky, S Guo, L Du, J Leid, G Feng, I Lokshina, ...
Immunity 54 (9), 2072-2088. e7, 2021
952021
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Artículos 1–20