| Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds MS Bonkowski, DA Sinclair Nature reviews Molecular cell biology 17 (11), 679-690, 2016 | 707 | 2016 |
| Reprogramming to recover youthful epigenetic information and restore vision Y Lu, B Brommer, X Tian, A Krishnan, M Meer, C Wang, DL Vera, Q Zeng, ... Nature 588 (7836), 124-129, 2020 | 525 | 2020 |
| Impairment of an endothelial NAD+-H2S signaling network is a reversible cause of vascular aging A Das, GX Huang, MS Bonkowski, A Longchamp, C Li, MB Schultz, ... Cell 173 (1), 74-89. e20, 2018 | 389 | 2018 |
| Targeted disruption of growth hormone receptor interferes with the beneficial actions of calorie restriction MS Bonkowski, JS Rocha, MM Masternak, KA Al Regaiey, A Bartke Proceedings of the National Academy of Sciences 103 (20), 7901-7905, 2006 | 358 | 2006 |
| Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction KA Al-Regaiey, MM Masternak, M Bonkowski, L Sun, A Bartke Endocrinology 146 (2), 851-860, 2005 | 263 | 2005 |
| Loss of epigenetic information as a cause of mammalian aging JH Yang, M Hayano, PT Griffin, JA Amorim, MS Bonkowski, ... Cell 186 (2), 305-326. e27, 2023 | 238 | 2023 |
| SIRT1 suppresses the epithelial-to-mesenchymal transition in cancer metastasis and organ fibrosis P Simic, EO Williams, EL Bell, JJ Gong, M Bonkowski, L Guarente Cell reports 3 (4), 1175-1186, 2013 | 228 | 2013 |
| Neuronal SIRT1 regulates endocrine and behavioral responses to calorie restriction DE Cohen, AM Supinski, MS Bonkowski, G Donmez, LP Guarente Genes & development 23 (24), 2812-2817, 2009 | 209 | 2009 |
| A conserved NAD+ binding pocket that regulates protein-protein interactions during aging J Li, MS Bonkowski, S Moniot, D Zhang, BP Hubbard, AJY Ling, ... Science 355 (6331), 1312-1317, 2017 | 207 | 2017 |
| Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity MS Bonkowski, FP Dominici, O Arum, JS Rocha, KA Al Regaiey, ... PloS one 4 (2), e4567, 2009 | 144 | 2009 |
| Alterations in oxygen consumption, respiratory quotient, and heat production in long-lived GHRKO and Ames dwarf mice, and short-lived bGH transgenic mice R Westbrook, MS Bonkowski, AD Strader, A Bartke Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2009 | 143 | 2009 |
| Insulin sensitivity as a key mediator of growth hormone actions on longevity MM Masternak, JA Panici, MS Bonkowski, LF Hughes, A Bartke Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2009 | 113 | 2009 |
| Age and life expectancy clocks based on machine learning analysis of mouse frailty MB Schultz, AE Kane, SJ Mitchell, MR MacArthur, E Warner, DS Vogel, ... Nature communications 11 (1), 4618, 2020 | 103 | 2020 |
| Stress resistance and aging: influence of genes and nutrition JM Harper, AB Salmon, Y Chang, M Bonkowski, A Bartke, RA Miller Mechanisms of ageing and development 127 (8), 687-694, 2006 | 95 | 2006 |
| Resveratrol improves vascular function and mitochondrial number but not glucose metabolism in older adults RM Pollack, N Barzilai, V Anghel, AS Kulkarni, A Golden, P O’Broin, ... Journals of Gerontology Series A: Biomedical Sciences and Medical Sciences …, 2017 | 94 | 2017 |
| Caloric restriction results in decreased expression of peroxisome proliferator-activated receptor superfamily in muscle of normal and long-lived growth hormone receptor/binding … MM Masternak, KA Al-Regaiey, MM Del Rosario Lim, MS Bonkowski, ... The Journals of Gerontology Series A: Biological Sciences and Medical …, 2005 | 87 | 2005 |
| Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency GLM Cagnone, TS Tsai, Y Makanji, P Matthews, J Gould, MS Bonkowski, ... Scientific reports 6 (1), 23229, 2016 | 84 | 2016 |
| Deviation of innate circadian period from 24 h reduces longevity in mice S Libert, MS Bonkowski, K Pointer, SD Pletcher, L Guarente Aging cell 11 (5), 794-800, 2012 | 84 | 2012 |
| Effects of caloric restriction on insulin pathway gene expression in the skeletal muscle and liver of normal and long-lived GHR-KO mice MM Masternak, KA Al-Regaiey, MMDR Lim, V Jimenez-Ortega, JA Panici, ... Experimental gerontology 40 (8-9), 679-684, 2005 | 83 | 2005 |
| Long-lived growth hormone receptor knockout mice show a delay in age-related changes of body composition and bone characteristics MS Bonkowski, RW Pamenter, JS Rocha, MM Masternak, JA Panici, ... The Journals of Gerontology Series A: Biological Sciences and Medical …, 2006 | 80 | 2006 |
David A. SinclairHarvard Medical School (Genetics)Dirección de correo verificada de hms.harvard.edu
