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Peter Stathopulos
Peter Stathopulos
Assistant Professor of Physiology and Pharmacology, Western University
Verified email at schulich.uwo.ca
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Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13109*2021
Structural and mechanistic insights into STIM1-mediated initiation of store-operated calcium entry
PB Stathopulos, L Zheng, GY Li, MJ Plevin, M Ikura
Cell 135 (1), 110-122, 2008
5502008
Sonication of proteins causes formation of aggregates that resemble amyloid
PB Stathopulos, GA Scholz, YM Hwang, JAO Rumfeldt, JR Lepock, ...
Protein Science 13 (11), 3017-3027, 2004
4682004
Stored Ca2+ depletion-induced oligomerization of stromal interaction molecule 1 (STIM1) via the EF-SAM region
PB Stathopulos, GY Li, MJ Plevin, JB Ames, M Ikura
Journal of Biological Chemistry 281 (47), 35855-35862, 2006
4662006
Cu/Zn superoxide dismutase mutants associated with amyotrophic lateral sclerosis show enhanced formation of aggregates in vitro
PB Stathopulos, JAO Rumfeldt, GA Scholz, RA Irani, HE Frey, ...
Proceedings of the National Academy of Sciences 100 (12), 7021-7026, 2003
3202003
STIM1 couples to ORAI1 via an intramolecular transition into an extended conformation
M Muik, M Fahrner, R Schindl, P Stathopulos, I Frischauf, I Derler, P Plenk, ...
The EMBO journal 30 (9), 1678-1689, 2011
2762011
STIM1/Orai1 coiled-coil interplay in the regulation of store-operated calcium entry
PB Stathopulos, R Schindl, M Fahrner, L Zheng, GM Gasmi-Seabrook, ...
Nature communications 4 (1), 2963, 2013
2392013
Initial activation of STIM1, the regulator of store-operated calcium entry
Y Zhou, P Srinivasan, S Razavi, S Seymour, P Meraner, A Gudlur, ...
Nature structural & molecular biology 20 (8), 973-981, 2013
2302013
Mitochondrial Ca2+ uniporter is a mitochondrial luminal redox sensor that augments MCU channel activity
Z Dong, S Shanmughapriya, D Tomar, N Siddiqui, S Lynch, N Nemani, ...
Molecular cell 65 (6), 1014-1028. e7, 2017
2222017
Stromal interaction molecule (STIM) 1 and STIM2 calcium sensing regions exhibit distinct unfolding and oligomerization kinetics
PB Stathopulos, L Zheng, M Ikura
Journal of biological chemistry 284 (2), 728-732, 2009
2192009
MCUR1 is a scaffold factor for the MCU complex function and promotes mitochondrial bioenergetics
D Tomar, Z Dong, S Shanmughapriya, DA Koch, T Thomas, NE Hoffman, ...
Cell reports 15 (8), 1673-1685, 2016
2172016
Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site
MT Mazhab-Jafari, CB Marshall, MJ Smith, GMC Gasmi-Seabrook, ...
Proceedings of the National Academy of Sciences 112 (21), 6625-6630, 2015
2052015
Biophysical characterization of the EF-hand and SAM domain containing Ca2+ sensory region of STIM1 and STIM2
L Zheng, PB Stathopulos, GY Li, M Ikura
Biochemical and biophysical research communications 369 (1), 240-246, 2008
1982008
Structural and functional conservation of key domains in InsP3 and ryanodine receptors
MD Seo, S Velamakanni, N Ishiyama, PB Stathopulos, AM Rossi, ...
Nature 483 (7387), 108-112, 2012
1902012
Auto-inhibitory role of the EF-SAM domain of STIM proteins in store-operated calcium entry
L Zheng, PB Stathopulos, R Schindl, GY Li, C Romanin, M Ikura
Proceedings of the National Academy of Sciences 108 (4), 1337-1342, 2011
1782011
A coiled-coil clamp controls both conformation and clustering of stromal interaction molecule 1 (STIM1)
M Fahrner, M Muik, R Schindl, C Butorac, P Stathopulos, L Zheng, I Jardin, ...
Journal of Biological Chemistry 289 (48), 33231-33244, 2014
1462014
A selective and cell-permeable mitochondrial calcium uniporter (MCU) inhibitor preserves mitochondrial bioenergetics after hypoxia/reoxygenation injury
JJ Woods, N Nemani, S Shanmughapriya, A Kumar, MQ Zhang, ...
ACS central science 5 (1), 153-166, 2019
1262019
Cholesterol modulates Orai1 channel function
I Derler, I Jardin, PB Stathopulos, M Muik, M Fahrner, V Zayats, ...
Science signaling 9 (412), ra10-ra10, 2016
1002016
Lactate elicits ER-mitochondrial Mg2+ dynamics to integrate cellular metabolism
CC Daw, K Ramachandran, BT Enslow, S Maity, B Bursic, MJ Novello, ...
Cell 183 (2), 474-489. e17, 2020
982020
Mechanism and thermodynamics of guanidinium chloride-induced denaturation of ALS-associated mutant Cu, Zn superoxide dismutases
JAO Rumfeldt, PB Stathopulos, A Chakrabarrty, JR Lepock, EM Meiering
Journal of molecular biology 355 (1), 106-123, 2006
972006
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Articles 1–20