| Regulatory T cells in autoimmune disease M Dominguez-Villar, DA Hafler Nature immunology 19 (7), 665-673, 2018 | 625 | 2018 |
| Identification of T helper type 1–like, Foxp3+ regulatory T cells in human autoimmune disease M Dominguez-Villar, CM Baecher-Allan, DA Hafler Nature medicine 17 (6), 673-675, 2011 | 540 | 2011 |
| The TIGIT/CD226 axis regulates human T cell function E Lozano, M Dominguez-Villar, V Kuchroo, DA Hafler The Journal of Immunology 188 (8), 3869-3875, 2012 | 485 | 2012 |
| Enhanced suppressor function of TIM‐3+FoxP3+ regulatory T cells AS Gautron, M Dominguez‐Villar, M de Marcken, DA Hafler European journal of immunology 44 (9), 2703-2711, 2014 | 227 | 2014 |
| The PI3K/AKT signaling pathway in regulatory T-cell development, stability, and function SL Pompura, M Dominguez-Villar Journal of leukocyte biology 103 (6), 1065-1076, 2018 | 215 | 2018 |
| Modulation of regulatory T cell function and stability by co-inhibitory receptors LE Lucca, M Dominguez-Villar Nature Reviews Immunology 20 (11), 680-693, 2020 | 156 | 2020 |
| TLR7 and TLR8 activate distinct pathways in monocytes during RNA virus infection M de Marcken, K Dhaliwal, AC Danielsen, AS Gautron, ... Science signaling 12 (605), eaaw1347, 2019 | 155 | 2019 |
| Droplet-based microfluidic platforms for single T cell secretion analysis of IL-10 cytokine T Konry, M Dominguez-Villar, C Baecher-Allan, DA Hafler, ML Yarmush Biosensors and Bioelectronics 26 (5), 2707-2710, 2011 | 142 | 2011 |
| TLR7 induces anergy in human CD4+ T cells M Dominguez-Villar, AS Gautron, M De Marcken, MJ Keller, DA Hafler Nature immunology 16 (1), 118-128, 2015 | 118 | 2015 |
| TIGIT signaling restores suppressor function of Th1 Tregs LE Lucca, PP Axisa, ER Singer, NM Nolan, M Dominguez-Villar, ... JCI insight 4 (3), 2019 | 107 | 2019 |
| AKT isoforms modulate Th1‐like Treg generation and function in human autoimmune disease A Kitz, M de Marcken, AS Gautron, M Mitrovic, DA Hafler, ... EMBO reports 17 (8), 1169-1183, 2016 | 103 | 2016 |
| Regulation of NFAT by poly (ADP-ribose) polymerase activity in T cells R Valdor, V Schreiber, L Saenz, T Martínez, A Muñoz-Suano, ... Molecular immunology 45 (7), 1863-1871, 2008 | 98 | 2008 |
| Activated β-catenin in Foxp3+ regulatory T cells links inflammatory environments to autoimmunity T Sumida, MR Lincoln, CM Ukeje, DM Rodriguez, H Akazawa, T Noda, ... Nature immunology 19 (12), 1391-1402, 2018 | 95 | 2018 |
| Molecular mechanisms underlying Th1-like Treg generation and function A Kitz, M Dominguez-Villar Cellular and molecular life sciences 74, 4059-4075, 2017 | 70 | 2017 |
| Oleic acid restores suppressive defects in tissue-resident FOXP3 Tregs from patients with multiple sclerosis SL Pompura, A Wagner, A Kitz, J LaPerche, N Yosef, M Dominguez-Villar, ... The Journal of clinical investigation 131 (2), 2021 | 69 | 2021 |
| CD2 costimulation reveals defective activity by human CD4+ CD25hi regulatory cells in patients with multiple sclerosis CM Baecher-Allan, CM Costantino, GL Cvetanovich, CW Ashley, G Beriou, ... The Journal of Immunology 186 (6), 3317-3326, 2011 | 67 | 2011 |
| Antigen-specific regulatory T cell therapy in autoimmune diseases and transplantation C Selck, M Dominguez-Villar Frontiers in immunology 12, 661875, 2021 | 59 | 2021 |
| Nonapoptotic and extracellular activity of granzyme B mediates resistance to regulatory T cell (Treg) suppression by HLA-DR− CD25hiCD127lo Tregs in multiple sclerosis and in … S Bhela, C Kempsell, M Manohar, M Dominguez-Villar, R Griffin, P Bhatt, ... The Journal of Immunology 194 (5), 2180-2189, 2015 | 56 | 2015 |
| Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells DM Kofler, A Marson, M Dominguez-Villar, S Xiao, VK Kuchroo, DA Hafler The Journal of clinical investigation 124 (6), 2513-2522, 2014 | 53 | 2014 |
| Fingolimod modulates T cell phenotype and regulatory T cell plasticity in vivo M Dominguez-Villar, K Raddassi, AC Danielsen, J Guarnaccia, DA Hafler Journal of autoimmunity 96, 40-49, 2019 | 49 | 2019 |
David HaflerProfessor of Neurology and Immunobiology, Yale UniversityDirección de correo verificada de yale.edu
