| MHC class II proteins and disease: a structural perspective EY Jones, L Fugger, JL Strominger, C Siebold Nature Reviews Immunology 6 (4), 271-282, 2006 | 540 | 2006 |
| Mutations in α-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans DA Keays, G Tian, K Poirier, GJ Huang, C Siebold, J Cleak, PL Oliver, ... Cell 128 (1), 45-57, 2007 | 476 | 2007 |
| Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension CH Coles, Y Shen, AP Tenney, C Siebold, GC Sutton, W Lu, JT Gallagher, ... Science 332 (6028), 484-488, 2011 | 362 | 2011 |
| Structural basis of Smoothened regulation by its extracellular domains EFX Byrne, R Sircar, PS Miller, G Hedger, G Luchetti, S Nachtergaele, ... Nature 535 (7613), 517-522, 2016 | 352 | 2016 |
| Initiation of T cell signaling by CD45 segregation at'close contacts' VT Chang, RA Fernandes, KA Ganzinger, SF Lee, C Siebold, J McColl, ... Nature immunology 17 (5), 574-582, 2016 | 304 | 2016 |
| A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization TS Walter, JM Diprose, CJ Mayo, C Siebold, MG Pickford, L Carter, ... Acta Crystallographica Section D: Biological Crystallography 61 (6), 651-657, 2005 | 284 | 2005 |
| Structural basis of semaphorin–plexin signalling BJC Janssen, RA Robinson, F Pérez-Brangulí, CH Bell, KJ Mitchell, ... Nature 467 (7319), 1118-1122, 2010 | 270 | 2010 |
| Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A) K Poirier, DA Keays, F Francis, Y Saillour, N Bahi, S Manouvrier, ... Human mutation 28 (11), 1055-1064, 2007 | 270 | 2007 |
| Interactions between Hedgehog proteins and their binding partners come into view PA Beachy, SG Hymowitz, RA Lazarus, DJ Leahy, C Siebold Genes & development 24 (18), 2001-2012, 2010 | 261 | 2010 |
| Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling G Luchetti, R Sircar, JH Kong, S Nachtergaele, A Sagner, EFX Byrne, ... Elife 5, e20304, 2016 | 225 | 2016 |
| Biochemical mechanisms of vertebrate hedgehog signaling JH Kong, C Siebold, R Rohatgi Development 146 (10), dev166892, 2019 | 215 | 2019 |
| Structure of the fungal β‐glucan‐binding immune receptor dectin‐1: Implications for function J Brown, CA O'Callaghan, ASJ Marshall, RJC Gilbert, C Siebold, ... Protein Science 16 (6), 1042-1052, 2007 | 201 | 2007 |
| Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex BJC Janssen, T Malinauskas, GA Weir, MZ Cader, C Siebold, EY Jones Nature structural & molecular biology 19 (12), 1293-1299, 2012 | 199 | 2012 |
| Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP M Lu, H Breyssens, V Salter, S Zhong, Y Hu, C Baer, I Ratnayaka, ... Cancer cell 23 (5), 618-633, 2013 | 197 | 2013 |
| Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP M Lu, H Breyssens, V Salter, S Zhong, Y Hu, C Baer, I Ratnayaka, ... Cancer cell 23 (5), 618-633, 2013 | 197 | 2013 |
| Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy C Siebold, BE Hansen, JR Wyer, K Harlos, RE Esnouf, A Svejgaard, ... Proceedings of the National Academy of Sciences 101 (7), 1999-2004, 2004 | 186 | 2004 |
| Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling S Nachtergaele, DM Whalen, LK Mydock, Z Zhao, T Malinauskas, ... elife 2, e01340, 2013 | 176 | 2013 |
| Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins J Elegheert, E Behiels, B Bishop, S Scott, RE Woolley, SC Griffiths, ... Nature protocols 13 (12), 2991-3017, 2018 | 173 | 2018 |
| Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1 T Malinauskas, AR Aricescu, W Lu, C Siebold, EY Jones Nature structural & molecular biology 18 (8), 886-893, 2011 | 171 | 2011 |
| Carbohydrate transporters of the bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) C Siebold, K Flükiger, R Beutler, B Erni FEBS letters 504 (3), 104-111, 2001 | 160 | 2001 |
E Yvonne JonesThe Sir Andrew McMichael Professor of Structural Immunology, University of OxfordDirección de correo verificada de strubi.ox.ac.uk
