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Humaira Gowher
Humaira Gowher
Associate Professor, Department of Biochemistry, Purdue University
Dirección de correo verificada de purdue.edu
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Biochemistry and biology of mammalian DNA methyltransferases
A Hermann, H Gowher, A Jeltsch
Cellular and Molecular Life Sciences CMLS 61, 2571-2587, 2004
7842004
Mechanism of stimulation of catalytic activity of Dnmt3A and Dnmt3B DNA-(cytosine-C5)-methyltransferases by Dnmt3L
H Gowher, K Liebert, A Hermann, G Xu, A Jeltsch
Journal of Biological Chemistry 280 (14), 13341-13348, 2005
4082005
Dnmt3a and Dnmt1 functionally cooperate during de novo methylation of DNA
M Fatemi, A Hermann, H Gowher, A Jeltsch
European journal of biochemistry 269 (20), 4981-4984, 2002
3352002
Enzymatic properties of recombinant Dnmt3a DNA methyltransferase from mouse: the enzyme modifies DNA in a non-processive manner and also methylates non-CpA sites
H Gowher, A Jeltsch
Journal of molecular biology 309 (5), 1201-1208, 2001
3062001
Chromatin targeting of de novo DNA methyltransferases by the PWWP domain
YZ Ge, MT Pu, H Gowher, HP Wu, JP Ding, A Jeltsch, GL Xu
Journal of Biological Chemistry 279 (24), 25447-25454, 2004
2682004
DNA of Drosophila melanogaster contains 5‐methylcytosine
H Gowher, O Leismann, A Jeltsch
The EMBO journal, 2000
2662000
Molecular enzymology of the catalytic domains of the Dnmt3a and Dnmt3b DNA methyltransferases
H Gowher, A Jeltsch
Journal of Biological Chemistry 277 (23), 20409-20414, 2002
2552002
Mammalian DNA methyltransferases: new discoveries and open questions
H Gowher, A Jeltsch
Biochemical Society Transactions 46 (5), 1191-1202, 2018
1462018
VEZF1 elements mediate protection from DNA methylation
J Dickson, H Gowher, R Strogantsev, M Gaszner, A Hair, G Felsenfeld, ...
PLoS genetics 6 (1), e1000804, 2010
1302010
The Escherichia coli dam DNA methyltransferase modifies DNA in a highly processive reaction
S Urig, H Gowher, A Hermann, C Beck, M Fatemi, A Humeny, A Jeltsch
Journal of molecular biology 319 (5), 1085-1096, 2002
1282002
Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy
H Gowher, A Jeltsch
Cancer biology & therapy 3 (11), 1062-1068, 2004
1222004
Mutational analysis of the catalytic domain of the murine Dnmt3a DNA-(cytosine C5)-methyltransferase
H Gowher, P Loutchanwoot, O Vorobjeva, V Handa, RZ Jurkowska, ...
Journal of molecular biology 357 (3), 928-941, 2006
1212006
Chromatin domains, insulators, and the regulation of gene expression
R Ghirlando, K Giles, H Gowher, T Xiao, Z Xu, H Yao, G Felsenfeld
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1819 (7), 644-651, 2012
1152012
DNMT3L facilitates DNA methylation partly by maintaining DNMT3A stability in mouse embryonic stem cells
N Veland, Y Lu, S Hardikar, S Gaddis, Y Zeng, B Liu, MR Estecio, ...
Nucleic acids research 47 (1), 152-167, 2019
1122019
De novo methylation of nucleosomal DNA by the mammalian Dnmt1 and Dnmt3A DNA methyltransferases
H Gowher, CJ Stockdale, R Goyal, H Ferreira, T Owen-Hughes, A Jeltsch
Biochemistry 44 (29), 9899-9904, 2005
1032005
Catalytic mechanism of DNA-(cytosine-C5)-methyltransferases revisited: covalent intermediate formation is not essential for methyl group transfer by the murine Dnmt3a enzyme
S Reither, F Li, H Gowher, A Jeltsch
Journal of molecular biology 329 (4), 675-684, 2003
832003
Molecular enzymology of the Eco RV DNA-(adenine-N6)-methyltransferase: kinetics of DNA binding and bending, kinetic mechanism and linear diffusion of the enzyme on DNA
H Gowher, A Jeltsch
Journal of molecular biology 303 (1), 93-110, 2000
812000
An epigenetic switch regulates de novo DNA methylation at a subset of pluripotency gene enhancers during embryonic stem cell differentiation
CJ Petell, L Alabdi, M He, P San Miguel, R Rose, H Gowher
Nucleic acids research 44 (16), 7605-7617, 2016
662016
Mutations in DNA methyltransferase DNMT3B in ICF syndrome affect its regulation by DNMT3L
ZH Xie, YN Huang, ZX Chen, AD Riggs, JP Ding, H Gowher, A Jeltsch, ...
Human molecular genetics 15 (9), 1375-1385, 2006
642006
Extra-coding RNAs regulate neuronal DNA methylation dynamics
KE Savell, NVN Gallus, RC Simon, JA Brown, JS Revanna, MK Osborn, ...
Nature communications 7 (1), 12091, 2016
612016
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20