| Nucleo‐cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein J Roth, M Dobbelstein, DA Freedman, T Shenk, AJ Levine The EMBO journal, 1998 | 871 | 1998 |
| p53-Responsive micrornas 192 and 215 are capable of inducing cell cycle arrest CJ Braun, X Zhang, I Savelyeva, S Wolff, UM Moll, T Schepeler, TF Ørntoft, ... Cancer research 68 (24), 10094-10104, 2008 | 558 | 2008 |
| Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment EM Alexandrova, AR Yallowitz, D Li, S Xu, R Schulz, DA Proia, G Lozano, ... Nature 523 (7560), 352-356, 2015 | 344 | 2015 |
| A polymorphic microsatellite that mediates induction of PIG3 by p53 A Contente, A Dittmer, MC Koch, J Roth, M Dobbelstein Nature genetics 30 (3), 315-320, 2002 | 320 | 2002 |
| p21/CDKN1A mediates negative regulation of transcription by p53 K Löhr, C Möritz, A Contente, M Dobbelstein Journal of Biological Chemistry 278 (35), 32507-32516, 2003 | 301 | 2003 |
| Exploiting replicative stress to treat cancer M Dobbelstein, CS Sørensen Nature reviews Drug discovery 14 (6), 405-423, 2015 | 295 | 2015 |
| Direct p53 Transcriptional Repression: In Vivo Analysis of CCAAT-Containing G2/M Promoters C Imbriano, A Gurtner, F Cocchiarella, S Di Agostino, V Basile, M Gostissa, ... Molecular and cellular biology 25 (9), 3737-3751, 2005 | 282 | 2005 |
| Nuclear export of the E1B 55‐kDa and E4 34‐kDa adenoviral oncoproteins mediated by a rev‐like signal sequence M Dobbelstein, J Roth, WT Kimberly, AJ Levine, T Shenk The EMBO journal, 1997 | 264 | 1997 |
| Targeting tumour-supportive cellular machineries in anticancer drug development M Dobbelstein, U Moll Nature reviews Drug discovery 13 (3), 179-196, 2014 | 256 | 2014 |
| The MDM2 oncoprotein binds specifically to RNA through its RING finger domain B Elenbaas, M Dobbelstein, J Roth, T Shenk, AJ Levine Molecular Medicine 2, 439-451, 1996 | 226 | 1996 |
| E2F1-inducible microRNA 449a/b suppresses cell proliferation and promotes apoptosis M Lize, S Pilarski, M Dobbelstein Cell Death & Differentiation 17 (3), 452-458, 2010 | 219 | 2010 |
| Protection against apoptosis by the vaccinia virus SPI-2 (B13R) gene product M Dobbelstein, T Shenk Journal of virology 70 (9), 6479-6485, 1996 | 210 | 1996 |
| Inactivation of the p53-homologue p73 by the mdm2-oncoprotein M Dobbelstein, S Wienzek, C König, J Roth Oncogene 18 (12), 2101-2106, 1999 | 209 | 1999 |
| Therapeutic ablation of gain-of-function mutant p53 in colorectal cancer inhibits Stat3-mediated tumor growth and invasion R Schulz-Heddergott, N Stark, SJ Edmunds, J Li, LC Conradi, ... Cancer Cell 34 (2), 298-314. e7, 2018 | 193 | 2018 |
| p53 induces the expression of its antagonist p73ΔN, establishing an autoregulatory feedback loop NN Kartasheva, A Contente, C Lenz-Stöppler, J Roth, M Dobbelstein Oncogene 21 (31), 4715-4727, 2002 | 190 | 2002 |
| Inactivation of p53 but not p73 by adenovirus type 5 E1B 55-kilodalton and E4 34-kilodalton oncoproteins J Roth, C König, S Wienzek, S Weigel, S Ristea, M Dobbelstein Journal of virology 72 (11), 8510-8516, 1998 | 175 | 1998 |
| MicroRNA-449 in cell fate determination M Lizé, A Klimke, M Dobbelstein Cell cycle 10 (17), 2874-2882, 2011 | 159 | 2011 |
| YB-1 relocates to the nucleus in adenovirus-infected cells and facilitates viral replication by inducing E2 gene expression through the E2 late promoter PS Holm, S Bergmann, K Jurchott, H Lage, K Brand, A Ladhoff, K Mantwill, ... Journal of Biological Chemistry 277 (12), 10427-10434, 2002 | 147 | 2002 |
| p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis F Talos, A Abraham, AV Vaseva, L Holembowski, SE Tsirka, A Scheel, ... Cell Death & Differentiation 17 (12), 1816-1829, 2010 | 135 | 2010 |
| Endogenous retrovirus drives hitherto unknown proapoptotic p63 isoforms in the male germ line of humans and great apes U Beyer, J Moll-Rocek, UM Moll, M Dobbelstein Proceedings of the National Academy of Sciences 108 (9), 3624-3629, 2011 | 128 | 2011 |
