Targeting the dynamic HSP90 complex in cancer J Trepel, M Mollapour, G Giaccone, L Neckers Nature reviews cancer 10 (8), 537-549, 2010 | 1676 | 2010 |
Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1 B Panaretou, G Siligardi, P Meyer, A Maloney, JK Sullivan, S Singh, ... Molecular cell 10 (6), 1307-1318, 2002 | 648 | 2002 |
Weak acid adaptation: the stress response that confers yeasts with resistance to organic acid food preservatives P Piper, CO Calderon, K Hatzixanthis, M Mollapour Microbiology 147 (10), 2635-2642, 2001 | 477 | 2001 |
Post-translational modifications of Hsp90 and their contributions to chaperone regulation M Mollapour, L Neckers Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1823 (3), 648-655, 2012 | 329 | 2012 |
Hog1 mitogen-activated protein kinase phosphorylation targets the yeast Fps1 aquaglyceroporin for endocytosis, thereby rendering cells resistant to acetic acid M Mollapour, PW Piper Molecular and cellular biology, 2007 | 325 | 2007 |
Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1α stabilization by glucose-dependent generation of … S Sudarshan, C Sourbier, HS Kong, K Block, VAV Romero, Y Yang, ... Molecular and cellular biology 29 (15), 4080-4090, 2009 | 245 | 2009 |
Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37 CK Vaughan, M Mollapour, JR Smith, A Truman, B Hu, VM Good, ... Molecular cell 31 (6), 886-895, 2008 | 241 | 2008 |
Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function M Mollapour, S Tsutsumi, AC Donnelly, K Beebe, MJ Tokita, MJ Lee, ... Molecular cell 37 (3), 333-343, 2010 | 195 | 2010 |
Global Phenotypic Analysis and Transcriptional Profiling Defines the Weak Acid Stress Response Regulon in Saccharomyces cerevisiae C Schuller, YM Mamnun, M Mollapour, G Krapf, M Schuster, BE Bauer, ... Molecular biology of the cell 15 (2), 706-720, 2004 | 194 | 2004 |
Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity M Mollapour, S Tsutsumi, AW Truman, W Xu, CK Vaughan, K Beebe, ... Molecular cell 41 (6), 672-681, 2011 | 187 | 2011 |
War1p, a novel transcription factor controlling weak acid stress response in yeast A Kren, YM Mamnun, BE Bauer, C Schüller, H Wolfger, K Hatzixanthis, ... Molecular and cellular biology 23 (5), 1775-1785, 2003 | 181 | 2003 |
Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50CDC37-AHA1 chaperone machine W Xu, M Mollapour, C Prodromou, S Wang, BT Scroggins, Z Palchick, ... Molecular cell 47 (3), 434-443, 2012 | 146 | 2012 |
Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity S Tsutsumi, M Mollapour, C Prodromou, CT Lee, B Panaretou, S Yoshida, ... Proceedings of the National Academy of Sciences 109 (8), 2937-2942, 2012 | 141 | 2012 |
Weak organic acid stress inhibits aromatic amino acid uptake by yeast, causing a strong influence of amino acid auxotrophies on the phenotypes of membrane transporter mutants BE Bauer, D Rossington, M Mollapour, Y Mamnun, K Kuchler, PW Piper European Journal of Biochemistry 270 (15), 3189-3195, 2003 | 139 | 2003 |
Post-translational modifications of Hsp90 and translating the chaperone code SJ Backe, RA Sager, MR Woodford, AM Makedon, M Mollapour Journal of Biological Chemistry 295 (32), 11099-11117, 2020 | 137 | 2020 |
Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors M Mollapour, D Bourboulia, K Beebe, MR Woodford, S Polier, A Hoang, ... Molecular cell 53 (2), 317-329, 2014 | 131 | 2014 |
MnSOD overexpression extends the yeast chronological (G0) life span but acts independently of Sir2p histone deacetylase to shorten the replicative life span of dividing cells N Harris, V Costa, M MacLean, M Mollapour, P Moradas-Ferreira, ... Free Radical Biology and Medicine 34 (12), 1599-1606, 2003 | 123 | 2003 |
Hog1p mitogen-activated protein kinase determines acetic acid resistance in Saccharomyces cerevisiae M Mollapour, PW Piper FEMS yeast research 6 (8), 1274-1280, 2006 | 111 | 2006 |
Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β … SH Millson, AW Truman, A Rácz, B Hu, B Panaretou, J Nuttall, ... The FEBS journal 274 (17), 4453-4463, 2007 | 110 | 2007 |
The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells PW Piper, GW Jones, D Bringloe, N Harris, M MacLean, M Mollapour Aging cell 1 (2), 149-157, 2002 | 101 | 2002 |