Quantitative analysis of NAD synthesis-breakdown fluxes L Liu, X Su, WJ Quinn, S Hui, K Krukenberg, DW Frederick, P Redpath, ... Cell metabolism 27 (5), 1067-1080. e5, 2018 | 444 | 2018 |
Effects of sex, strain, and energy intake on hallmarks of aging in mice SJ Mitchell, J Madrigal-Matute, M Scheibye-Knudsen, E Fang, M Aon, ... Cell metabolism 23 (6), 1093-1112, 2016 | 411 | 2016 |
SirT1 regulates adipose tissue inflammation MP Gillum, ME Kotas, DM Erion, R Kursawe, P Chatterjee, KT Nead, ... Diabetes 60 (12), 3235-3245, 2011 | 337 | 2011 |
Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle DW Frederick, E Loro, L Liu, A Davila, K Chellappa, IM Silverman, ... Cell metabolism 24 (2), 269-282, 2016 | 329 | 2016 |
Nicotinamide improves aspects of healthspan, but not lifespan, in mice SJ Mitchell, M Bernier, MA Aon, S Cortassa, EY Kim, EF Fang, ... Cell metabolism 27 (3), 667-676. e4, 2018 | 309 | 2018 |
A high-fat, ketogenic diet causes hepatic insulin resistance in mice, despite increasing energy expenditure and preventing weight gain FR Jornayvaz, MJ Jurczak, HY Lee, AL Birkenfeld, DW Frederick, ... American Journal of Physiology-Endocrinology and Metabolism 299 (5), E808-E815, 2010 | 247 | 2010 |
SGLT2 deletion improves glucose homeostasis and preserves pancreatic β-cell function MJ Jurczak, HY Lee, AL Birkenfeld, FR Jornayvaz, DW Frederick, ... Diabetes 60 (3), 890-898, 2011 | 241 | 2011 |
Deletion of the mammalian INDY homolog mimics aspects of dietary restriction and protects against adiposity and insulin resistance in mice AL Birkenfeld, HY Lee, F Guebre-Egziabher, TC Alves, MJ Jurczak, ... Cell metabolism 14 (2), 184-195, 2011 | 202 | 2011 |
Deletion of the α-arrestin protein Txnip in mice promotes adiposity and adipogenesis while preserving insulin sensitivity WA Chutkow, AL Birkenfeld, JD Brown, HY Lee, DW Frederick, ... Diabetes 59 (6), 1424-1434, 2010 | 183 | 2010 |
N-acylphosphatidylethanolamine, a gut-derived circulating factor induced by fat ingestion, inhibits food intake MP Gillum, D Zhang, XM Zhang, DM Erion, RA Jamison, C Choi, J Dong, ... Cell 135 (5), 813-824, 2008 | 168 | 2008 |
Apolipoprotein CIII overexpressing mice are predisposed to diet‐induced hepatic steatosis and hepatic insulin resistance HY Lee, AL Birkenfeld, FR Jornayvaz, MJ Jurczak, S Kanda, V Popov, ... Hepatology 54 (5), 1650-1660, 2011 | 133 | 2011 |
Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism DW Frederick, JG Davis, A Dávila, B Agarwal, S Michan, MA Puchowicz, ... Journal of Biological Chemistry 290 (3), 1546-1558, 2015 | 102 | 2015 |
Rapamycin blocks induction of the thermogenic program in white adipose tissue CM Tran, S Mukherjee, L Ye, DW Frederick, M Kissig, JG Davis, ... Diabetes 65 (4), 927-941, 2016 | 82 | 2016 |
Influence of the hepatic eukaryotic initiation factor 2α (eIF2α) endoplasmic reticulum (ER) stress response pathway on insulin-mediated ER stress and hepatic and peripheral … AL Birkenfeld, HY Lee, S Majumdar, MJ Jurczak, JP Camporez, ... Journal of Biological Chemistry 286 (42), 36163-36170, 2011 | 82 | 2011 |
Rapamycin maintains NAD+/NADH redox homeostasis in muscle cells Z Zhang, HN Xu, S Li, A Davila Jr, K Chellappa, JG Davis, Y Guan, ... Aging (albany NY) 12 (18), 17786, 2020 | 22 | 2020 |
Complementary NAD+ replacement strategies fail to functionally protect dystrophin-deficient muscle DW Frederick, AV McDougal, M Semenas, J Vappiani, A Nuzzo, JC Ulrich, ... Skeletal Muscle 10, 1-14, 2020 | 20 | 2020 |
Accumulation of 3-hydroxytetradecenoic acid: Cause or corollary of glucolipotoxic impairment of pancreatic β-cell bioenergetics? NM Doliba, Q Liu, C Li, J Chen, P Chen, C Liu, DW Frederick, JA Baur, ... Molecular metabolism 4 (12), 926-939, 2015 | 16 | 2015 |
Stable isotope labeling by essential nutrients in cell culture (SILEC) for accurate measurement of nicotinamide adenine dinucleotide metabolism DW Frederick, S Trefely, A Buas, J Goodspeed, J Singh, C Mesaros, ... Analyst 142 (23), 4431-4437, 2017 | 11 | 2017 |
Influence of the hepatic eIF2 {alpha} ER stress response pathway on insulin mediated ER stress, Hepatic and Peripheral Glucose Metabolism AL Birkenfeld, HY Lee, S Majumdar, MJ Juzcak, J Camporez, ... J Biol Chem 286 (42), 36163-70, 2011 | 6 | 2011 |
Imaging redox state in mouse muscles of different ages L Moon, DW Frederick, JA Baur, LZ Li Oxygen Transport to Tissue XXXIX, 51-57, 2017 | 5 | 2017 |