| tyk2, prototype of a novel class of non-receptor tyrosine kinase genes. I Firmbach-Kraft, M Byers, T Shows, R Dalla-Favera, JJ Krolewski Oncogene 5, 1329-1336, 1990 | 445 | 1990 |
| Stat recruitment by tyrosine-phosphorylated cytokine receptors: an ordered reversible affinity-driven process AC Greenlund, MO Morales, BL Viviano, H Yan, J Krolewski, ... Immunity 2, 677-687, 1995 | 397 | 1995 |
| Activation of Stat3 in v-Src-transformed fibroblasts requires cooperation of Jak1 kinase activity Y Zhang, J Turkson, C Carter-Su, T Smithgall, A Levitzki, A Kraker, ... J Biol Chem 275, 24935-24944, 2000 | 254 | 2000 |
| Direct binding to and tyrosine phosphorylation of the a subunit of the type I interferon receptor by p135tyk2 tyrosine kinase O Colamonici, H Yan, P Domanski, R Handa, D Smalley, J Mullersman, ... Mol Cell Biol 14, 8133-8142, 1994 | 249 | 1994 |
| Phosphorylated interferon‐alpha receptor 1 subunit (IFNaR1) acts as a docking site for the latent form of the 113 kDa STAT2 protein. H Yan, K Krishnan, AC Greenlund, S Gupta, JT Lim, RD Schreiber, ... EMBO J 15, 1064-1074, 1996 | 246 | 1996 |
| The SH2 domains of Stat1 and Stat2 mediate multiple interactions in the transduction of IFN‐alpha signals. S Gupta, H Yan, LH Wong, S Ralph, J Krolewski, C Schindler EMBO J 15, 1075-1084, 1996 | 225 | 1996 |
| p135tyk2, an interferon-alpha-activated tyrosine kinase, is physically associated with an interferon-alpha receptor. OR Colamonici, H Uyttendaele, P Domanski, H Yan, JJ Krolewski J Biol Chem 269, 3518-3522, 1994 | 216 | 1994 |
| Quantitative forward mutation assay in Salmonella typhimurium using 8-azaguanine resistance as a genetic marker. TR Skopek, HL Liber, JJ Krolewski, WG Thilly PNAS 75, 410-414, 1978 | 214 | 1978 |
| MicroRNA-141 suppresses prostate cancer stem cells and metastasis by targeting a cohort of pro-metastasis genes C Liu, R Liu, D Zhang, Q Deng, B Liu, HP Chao, K Rycaj, Y Takata, K Lin, ... Nature Comm 8, 14270, 2017 | 206 | 2017 |
| Phosphorylation and specific ubiquitin acceptor sites are required for ubiquitination and degradation of the IFNAR1 subunit of type I interferon receptor KGS Kumar, JJ Krolewski, SY Fuchs J Biol Chem 279, 46614-46620, 2004 | 176 | 2004 |
| Association of the interferon-dependent tyrosine kinase Tyk-2 with the hematopoietic cell phosphatase A Yetter, S Uddin, JJ Krolewski, H Jiao, T Yi, LC Platanias J Biol Chem 270, 18179-18182, 1995 | 155 | 1995 |
| Beta interferon and oncostatin M activate Raf-1 and mitogen-activated protein kinase through a JAK1-dependent pathway LF Stancato, M Sakatsume, M David, P Dent, F Dong, EF Petricoin, ... Mol Cell Biol 17, 3833–3840, 1997 | 138 | 1997 |
| Identification and chromosomal mapping of new human tyrosine kinase genes. JJ Krolewski, R Lee, R Eddy, TB Shows, R Dalla-Favera Oncogene 5, 277-282, 1990 | 136 | 1990 |
| Molecular characterization of an alpha interferon receptor 1 subunit (IFNaR1) domain required for TYK2 binding and signal transduction H Yan, K Krishnan, JTE Lim, LG Contillo, JJ Krolewski Mol Cell Biol 16, 2074-2082, 1996 | 126 | 1996 |
| Gene-locus mutation assays in diploid human lymphoblast lines WG Thilly, JG DeLuca, EE Furth, H Hoppe, DA Kaden, JJ Krolewski, ... Chemical Mutagens 6, 331-364, 1980 | 114 | 1980 |
| A region of the β subunit of the interferon α receptor different from box 1 interacts with Jak1 and is sufficient to activate the Jak-Stat pathway and induce an antiviral state P Domanski, E Fish, OW Nadeau, M Witte, LC Platanias, H Yan, ... J Biol Chem 272, 26388-26393, 1997 | 113 | 1997 |
| Sporadic breast cancers exhibit loss of heterozygosity on chromosome segment 10q23 close to the Cowden disease locus B Singh, MM Ittmann, JJ Krolewski Gene Chromosomes Cancer 21, 166-171, 1998 | 111 | 1998 |
| Direct interaction of Jak1 and v-Abl is required for v-Abl-induced activation of STATs and proliferation NN Danial, JA Losman, T Lu, N Yip, K Krishnan, JJ Krolewski, SP Goff, ... Mol Cell Biol 18, 6795-6804, 1998 | 94 | 1998 |
| Common mutations in BRCA1 and BRCA2 do not contribute to early prostate cancer in Jewish men KL Nastiuk, M Mansukhani, MB Terry, P Kularatne, MA Rubin, J Melamed, ... Prostate 40, 172-177, 1999 | 85 | 1999 |
| Opportunities and challenges in combination gene cancer therapy [REVIEW] KL Nastiuk, JJ Krolewski Adv Drug Delivery Rev 98, 35-40, 2016 | 82 | 2016 |
Kent L. NastiukRoswell Park Cancer InstiuteVerified email at roswellpark.org
