| The receptor tyrosine kinase AXL is required at multiple steps of the metastatic cascade during HER2-positive breast cancer progression MA Goyette, S Duhamel, L Aubert, A Pelletier, P Savage, MP Thibault, ... Cell reports 23 (5), 1476-1490, 2018 | 141 | 2018 |
| ERRα mediates metabolic adaptations driving lapatinib resistance in breast cancer G Deblois, HW Smith, IS Tam, SP Gravel, M Caron, P Savage, DP Labbé, ... Nature communications 7 (1), 12156, 2016 | 118 | 2016 |
| YAP-induced resistance of cancer cells to antitubulin drugs is modulated by a Hippo-independent pathway Y Zhao, P Khanal, P Savage, YM She, TD Cyr, X Yang Cancer research 74 (16), 4493-4503, 2014 | 98 | 2014 |
| Epigenetic switch–induced viral mimicry evasion in chemotherapy-resistant breast cancer G Deblois, SAM Tonekaboni, G Grillo, C Martinez, YI Kao, F Tai, I Ettayebi, ... Cancer discovery 10 (9), 1312-1329, 2020 | 95 | 2020 |
| Targeting EZH2 reactivates a breast cancer subtype-specific anti-metastatic transcriptional program A Hirukawa, HW Smith, D Zuo, CR Dufour, P Savage, N Bertos, ... Nature communications 9 (1), 2547, 2018 | 79 | 2018 |
| A targetable EGFR-dependent tumor-initiating program in breast cancer P Savage, A Blanchet-Cohen, T Revil, D Badescu, SMI Saleh, YC Wang, ... Cell reports 21 (5), 1140-1149, 2017 | 77 | 2017 |
| Dual MAPK inhibition is an effective therapeutic strategy for a subset of class II BRAF mutant melanomas M Dankner, M Lajoie, D Moldoveanu, TT Nguyen, P Savage, S Rajkumar, ... Clinical Cancer Research 24 (24), 6483-6494, 2018 | 66 | 2018 |
| Lyn modulates Claudin-2 expression and is a therapeutic target for breast cancer liver metastasis S Tabariès, MG Annis, BE Hsu, CE Tam, P Savage, M Park, PM Siegel Oncotarget 6 (11), 9476, 2015 | 56 | 2015 |
| Sumoylation of Krüppel-like factor 4 inhibits pluripotency induction but promotes adipocyte differentiation S Tahmasebi, M Ghorbani, P Savage, K Yan, G Gocevski, L Xiao, L You, ... Journal of Biological Chemistry 288 (18), 12791-12804, 2013 | 51 | 2013 |
| The SUMO conjugating enzyme Ubc9 is required for inducing and maintaining stem cell pluripotency S Tahmasebi, M Ghorbani, P Savage, G Gocevski, XJ Yang Stem cells 32 (4), 1012-1020, 2014 | 41 | 2014 |
| Activation of the pattern recognition receptor NOD1 augments colon cancer metastasis HY Jiang, S Najmeh, G Martel, E MacFadden-Murphy, R Farias, P Savage, ... Protein & cell 11 (3), 187-201, 2020 | 38 | 2020 |
| STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer SP Totten, YK Im, E Cepeda Cañedo, O Najyb, A Nguyen, S Hébert, ... Nature Communications 12 (1), 3299, 2021 | 37 | 2021 |
| Incidence and predictors of postoperative ileus after loop ileostomy closure: a systematic review and meta-analysis R Garfinkle, P Savage, M Boutros, T Landry, P Reynier, N Morin, ... Surgical endoscopy 33, 2430-2443, 2019 | 34 | 2019 |
| Chemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors P Savage, A Pacis, H Kuasne, L Liu, D Lai, A Wan, M Dankner, ... Communications biology 3 (1), 310, 2020 | 31 | 2020 |
| An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis HW Smith, A Hirukawa, V Sanguin-Gendreau, I Nandi, CR Dufour, D Zuo, ... Nature communications 10 (1), 2901, 2019 | 27 | 2019 |
| Invasive growth associated with Cold-Inducible RNA-Binding Protein expression drives recurrence of surgically resected brain metastases M Dankner, M Caron, T Al-Saadi, WQ Yu, V Ouellet, R Ezzeddine, ... Neuro-oncology 23 (9), 1470-1480, 2021 | 24 | 2021 |
| The effect of the American Joint Committee on Cancer eighth edition on breast cancer staging and prognostication P Savage, N Yu, S Dumitra, S Meterissian European Journal of Surgical Oncology 45 (10), 1817-1820, 2019 | 15 | 2019 |
| DZ-2384 has a superior preclinical profile to taxanes for the treatment of triple-negative breast cancer and is synergistic with anti-CTLA-4 immunotherapy C Bernier, A Soliman, M Gravel, M Dankner, P Savage, K Petrecca, ... Anti-Cancer Drugs 29 (8), 774-785, 2018 | 14 | 2018 |
| Canadian MD-Ph. D. Programs Produce Impactful Physician-Scientists: The McGill Experience TE Zhou, PA Savage, MJ Eisenberg Journal of Biomedical Education 2016, 1-4, 2016 | 13 | 2016 |
| Co-dependency for MET and FGFR1 in basal triple-negative breast cancers VYC Sung, JF Knight, RM Johnson, YE Stern, SM Saleh, P Savage, ... NPJ Breast Cancer 7 (1), 36, 2021 | 10 | 2021 |
Morag ParkProfessor of Oncology and Biochemistry, McGill University, Director Goodman Cancer Research CentreDirección de correo verificada de mcgill.ca
