| Structure-guided design and optimization of small molecules targeting the protein–protein interaction between the von Hippel–Lindau (VHL) E3 ubiquitin ligase and the hypoxia … C Galdeano, MS Gadd, P Soares, S Scaffidi, I Van Molle, I Birced, ... Journal of Medicinal Chemistry 57 (20), 8657-8663, 2014 | 386 | 2014 |
| Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition J Frost, C Galdeano, P Soares, MS Gadd, KM Grzes, L Ellis, O Epemolu, ... Nature communications 7 (1), 13312, 2016 | 196 | 2016 |
| Gastrointestinal dysmotility in 5-fluorouracil-induced intestinal mucositis outlasts inflammatory process resolution PMG Soares, JMSC Mota, AS Gomes, RB Oliveira, AMS Assreuy, ... Cancer chemotherapy and pharmacology 63, 91-98, 2008 | 164 | 2008 |
| Antinociceptive properties of the essential oil of Ocimum gratissimum L.(Labiatae) in mice M Rabelo, EP Souza, PMG Soares, AV Miranda, FJA Matos, DN Criddle Brazilian Journal of Medical and Biological Research 36, 521-524, 2003 | 158 | 2003 |
| Group-based optimization of potent and cell-active inhibitors of the von Hippel–Lindau (VHL) E3 ubiquitin ligase: structure–activity relationships leading to the chemical probe … P Soares, MS Gadd, J Frost, C Galdeano, L Ellis, O Epemolu, S Rocha, ... Journal of medicinal chemistry 61 (2), 599-618, 2018 | 137 | 2018 |
| Role of cytokines (TNF-α, IL-1β and KC) in the pathogenesis of CPT-11-induced intestinal mucositis in mice: effect of pentoxifylline and thalidomide MLP Melo, GAC Brito, RC Soares, SBLM Carvalho, JV Silva, PMG Soares, ... Cancer chemotherapy and pharmacology 61, 775-784, 2008 | 136 | 2008 |
| Isothiazolinone biocides: chemistry, biological, and toxicity profiles V Silva, C Silva, P Soares, EM Garrido, F Borges, J Garrido Molecules 25 (4), 991, 2020 | 129 | 2020 |
| Role of the NO/cGMP/KATP pathway in the protective effects of sildenafil against ethanol‐induced gastric damage in rats JVR Medeiros, GG Gadelha, SJ Lima, JA Garcia, PMG Soares, AA Santos, ... British Journal of Pharmacology 153 (4), 721-727, 2008 | 128 | 2008 |
| Antispasmodic effect of Mentha piperita essential oil on tracheal smooth muscle of rats AAS de Sousa, PMG Soares, ANS de Almeida, AR Maia, EP de Souza, ... Journal of ethnopharmacology 130 (2), 433-436, 2010 | 119 | 2010 |
| Hydrogen sulfide prevents ethanol-induced gastric damage in mice: role of ATP-sensitive potassium channels and capsaicin-sensitive primary afferent neurons JVR Medeiros, VH Bezerra, AS Gomes, ALR Barbosa, RCP Lima-Junior, ... Journal of Pharmacology and Experimental Therapeutics 330 (3), 764-770, 2009 | 108 | 2009 |
| Regulatory role of Lactobacillus acidophilus on inflammation and gastric dysmotility in intestinal mucositis induced by 5-fluorouracil in mice PFC Justino, LFM Melo, AF Nogueira, CM Morais, WO Mendes, ... Cancer chemotherapy and pharmacology 75, 559-567, 2015 | 103 | 2015 |
| Inhaled 1, 8‐cineole reduces inflammatory parameters in airways of Ovalbumin‐challenged Guinea Pigs VPD Bastos, AS Gomes, FJB Lima, TS Brito, PMG Soares, JPM Pinho, ... Basic & clinical pharmacology & toxicology 108 (1), 34-39, 2011 | 101 | 2011 |
| Treatment with Saccharomyces boulardii reduces the inflammation and dysfunction of the gastrointestinal tract in 5-fluorouracil-induced intestinal mucositis in mice PFC Justino, LFM Melo, AF Nogueira, JVG Costa, LMN Silva, CM Santos, ... British journal of nutrition 111 (9), 1611-1621, 2014 | 98 | 2014 |
| Inflammatory intestinal damage induced by 5-fluorouracil requires IL-4 PMG Soares, JMSC Mota, EP Souza, PFC Justino, AX Franco, FQ Cunha, ... Cytokine 61 (1), 46-49, 2013 | 95 | 2013 |
| (−)-α-Bisabolol-induced gastroprotection is associated with reduction in lipid peroxidation, superoxide dismutase activity and neutrophil migration NFM Rocha, GV de Oliveira, FYR de Araújo, ERV Rios, AMR Carvalho, ... European Journal of Pharmaceutical Sciences 44 (4), 455-461, 2011 | 91 | 2011 |
| Comparative study of the anti-edematogenic effects of anethole and estragole EL Ponte, PL Sousa, MVAP Rocha, PMG Soares, AN Coelho-de-Souza, ... Pharmacological Reports 64 (4), 984-990, 2012 | 88 | 2012 |
| Evaluation of mucositis induced by irinotecan after microbial colonization in germ-free mice SHSP Pedroso, AT Vieira, RW Bastos, JS Oliveira, CT Cartelle, ... Microbiology 161 (10), 1950-1960, 2015 | 86 | 2015 |
| Oxidative stress in acute pancreatitis: lost in translation? JA Armstrong, N Cash, PMG Soares, M Souza, R Sutton, DN Criddle Free radical research 47 (11), 917-933, 2013 | 82 | 2013 |
| Effects of anethole and structural analogues on the contractility of rat isolated aorta: Involvement of voltage-dependent Ca2+-channels PMG Soares, RF Lima, A de Freitas Pires, EP Souza, AMS Assreuy, ... Life sciences 81 (13), 1085-1093, 2007 | 78 | 2007 |
| Antioxidant therapy: Still in search of the ‘magic bullet’ S Benfeito, C Oliveira, P Soares, C Fernandes, T Silva, J Teixeira, ... Mitochondrion 13 (5), 427-435, 2013 | 76 | 2013 |
