| Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM JG Viniegra, N Martínez, P Modirassari, JH Losa, CP Cobo, VJSA Lobo, ... Journal of Biological Chemistry 280 (6), 4029-4036, 2005 | 350 | 2005 |
| A role for the p38 mitogen-activated protein kinase pathway in the transcriptional activation of p53 on genotoxic stress by chemotherapeutic agents R Sanchez-Prieto, JM Rojas, Y Taya, JS Gutkind Cancer research 60 (9), 2464-2472, 2000 | 349 | 2000 |
| Polymorphisms G691S/S904S of RET as Genetic Modifiers of MEN 2A M Robledo, L Gil, M Pollán, A Cebrián, S Ruíz, M Azanedo, J Benitez, ... Cancer Research 63 (8), 1814-1817, 2003 | 177 | 2003 |
| Algunas experiencias didácticas en el entorno de la plataforma Moodle R Casales, J Rojas, G Paulí Revista de informática educativa y medios audiovisuales 5 (19), 1-10, 2008 | 173 | 2008 |
| Gestión educativa en la sociedad del conocimiento JMR Quiñones Coop. Editorial Magisterio, 2006 | 163 | 2006 |
| The cyclopentenone 15-deoxy-Δ12,14-prostaglandin J2 binds to and activates H-Ras JL Oliva, D Pérez-Sala, A Castrillo, N Martínez, FJ Cañada, L Boscá, ... Proceedings of the National Academy of Sciences 100 (8), 4772-4777, 2003 | 144 | 2003 |
| Natural occurrence of drug resistance mutations in the reverse transcriptase of human immunodeficiency virus type 1 isolates I Nájera, DD Richman, I Olivares, JM Rojas, MA Peinado, M Perucho, ... AIDS research and human retroviruses 10 (11), 1479-1488, 1994 | 123 | 1994 |
| Immortalized mouse mammary fibroblasts lacking dioxin receptor have impaired tumorigenicity in a subcutaneous mouse xenograft model S Mulero-Navarro, E Pozo-Guisado, PA Pérez-Mancera, ... Journal of Biological Chemistry 280 (31), 28731-28741, 2005 | 108 | 2005 |
| Mammalian son of sevenless Guanine nucleotide exchange factors: old concepts and new perspectives JM Rojas, JL Oliva, E Santos Genes & cancer 2 (3), 298-305, 2011 | 104 | 2011 |
| Clinical value of p53, c‐erbB‐2, CEA and CA125 regarding relapse, metastasis and death in resectable non‐small cell lung cancer M Pollán, G Varela, A Torres, M de la Torre, MD Ludeña, MD Ortega, ... International journal of cancer 107 (5), 781-790, 2003 | 101 | 2003 |
| Aplidin® induces JNK-dependent apoptosis in human breast cancer cells via alteration of glutathione homeostasis, Rac1 GTPase activation, and MKP-1 phosphatase downregulation L Gonzalez-Santiago, Y Suárez, N Zarich, MJ Munoz-Alonso, A Cuadrado, ... Cell Death & Differentiation 13 (11), 1968-1981, 2006 | 98 | 2006 |
| SJ23B, a jatrophane diterpene activates classical PKCs and displays strong activity against HIV in vitro LM Bedoya, N Márquez, N Martínez, S Gutiérrez-Eisman, A Alvarez, ... Biochemical pharmacology 77 (6), 965-978, 2009 | 90 | 2009 |
| Grb2 is a negative modulator of the intrinsic Ras-GEF activity of hSos1 N Zarich, JL Oliva, N Martínez, R Jorge, A Ballester, S Gutiérrez-Eisman, ... Molecular biology of the cell 17 (8), 3591-3597, 2006 | 88 | 2006 |
| Endothelial nitric oxide synthase regulates N-Ras activation on the Golgi complex of antigen-stimulated T cells S Ibiza, A Pérez-Rodríguez, Á Ortega, A Martínez-Ruiz, O Barreiro, ... Proceedings of the National Academy of Sciences 105 (30), 10507-10512, 2008 | 87 | 2008 |
| Expression of alternative forms of Ras exchange factors GRF and SOS1 in different human tissues and cell lines. C Guerrero, JM Rojas, M Chedid, LM Esteban, DB Zimonjic, NC Popescu, ... Oncogene 12 (5), 1097-1107, 1996 | 78* | 1996 |
| SPROUTY-2 and E-cadherin regulate reciprocally and dictate colon cancer cell tumourigenicity A Barbáchano, P Ordóñez-Morán, JM García, A Sánchez, F Pereira, ... Oncogene 29 (34), 4800-4813, 2010 | 77 | 2010 |
| Cell density-dependent inhibition of epidermal growth factor receptor signaling by p38α mitogen-activated protein kinase via Sprouty2 downregulation A Swat, I Dolado, JM Rojas, AR Nebreda Molecular and cellular biology 29 (12), 3332-3343, 2009 | 66 | 2009 |
| Modification and activation of Ras proteins by electrophilic prostanoids with different structure are site-selective M Renedo, J Gayarre, CA García-Domínguez, A Pérez-Rodríguez, ... Biochemistry 46 (22), 6607-6616, 2007 | 66 | 2007 |
| Sprouty-2 overexpression in C2C12 cells confers myogenic differentiation properties in the presence of FGF2 C De Alvaro, N Martinez, JM Rojas, M Lorenzo Molecular biology of the cell 16 (9), 4454-4461, 2005 | 61 | 2005 |
| Characterization of genetic variation and 3'-azido-3'-deoxythymidine-resistance mutations of human immunodeficiency virus by the RNase A mismatch cleavage method. C Lopez-Galindez, JM Rojas, R Najera, DD Richman, M Perucho Proceedings of the National Academy of Sciences 88 (10), 4280-4284, 1991 | 60 | 1991 |
