| Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody D Pinto, YJ Park, M Beltramello, AC Walls, MA Tortorici, S Bianchi, ... Nature 583 (7815), 290-295, 2020 | 1828 | 2020 |
| Circulating SARS-CoV-2 spike N439K variants maintain fitness while evading antibody-mediated immunity EC Thomson, LE Rosen, JG Shepherd, R Spreafico, A da Silva Filipe, ... Cell 184 (5), 1171-1187. e20, 2021 | 643* | 2021 |
| A perspective on potential antibody-dependent enhancement of SARS-CoV-2 AM Arvin, K Fink, MA Schmid, A Cathcart, R Spreafico, ... Nature 584 (7821), 353-363, 2020 | 559 | 2020 |
| Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms MA Tortorici, M Beltramello, FA Lempp, D Pinto, HV Dang, LE Rosen, ... Science 370 (6519), 950-957, 2020 | 503 | 2020 |
| From big data to precision medicine T Hulsen, SS Jamuar, AR Moody, JH Karnes, O Varga, S Hedensted, ... Frontiers in medicine 6, 34, 2019 | 385 | 2019 |
| Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes E Viganò, CE Diamond, R Spreafico, A Balachander, RM Sobota, ... Nature communications 6 (1), 8761, 2015 | 360 | 2015 |
| Type III interferons disrupt the lung epithelial barrier upon viral recognition A Broggi, S Ghosh, B Sposito, R Spreafico, F Balzarini, A Lo Cascio, ... Science 369 (6504), 706-712, 2020 | 347 | 2020 |
| Exhaustion-associated regulatory regions in CD8+ tumor-infiltrating T cells GP Mognol, R Spreafico, V Wong, JP Scott-Browne, S Togher, ... Proceedings of the National Academy of Sciences 114 (13), E2776-E2785, 2017 | 295 | 2017 |
| Cutting edge: the NLRP3 inflammasome links complement-mediated inflammation and IL-1β release F Laudisi, R Spreafico, M Evrard, TR Hughes, B Mandriani, M Kandasamy, ... The Journal of Immunology 191 (3), 1006-1010, 2013 | 209 | 2013 |
| The dual function monoclonal antibodies VIR-7831 and VIR-7832 demonstrate potent in vitro and in vivo activity against SARS-CoV-2 AL Cathcart, C Havenar-Daughton, FA Lempp, D Ma, M Schmid, ... bioRxiv, 2021 | 203 | 2021 |
| The interferon landscape along the respiratory tract impacts the severity of COVID-19 B Sposito, A Broggi, L Pandolfi, S Crotta, N Clementi, R Ferrarese, S Sisti, ... Cell 184 (19), 4953-4968. e16, 2021 | 192 | 2021 |
| Endogenous oxidized phospholipids reprogram cellular metabolism and boost hyperinflammation M Di Gioia, R Spreafico, JR Springstead, MM Mendelson, R Joehanes, ... Nature immunology 21 (1), 42-53, 2020 | 129 | 2020 |
| Antibody-mediated rejection in lung transplantation: clinical outcomes and donor-specific antibody characteristics A Roux, IB Le Lan, S Holifanjaniaina, KA Thomas, AM Hamid, C Picard, ... American Journal of Transplantation 16 (4), 1216-1228, 2016 | 125* | 2016 |
| Uric acid-driven Th17 differentiation requires inflammasome-derived IL-1 and IL-18 C Conforti-Andreoni, R Spreafico, HL Qian, N Riteau, B Ryffel, ... The Journal of Immunology 187 (11), 5842-5850, 2011 | 114 | 2011 |
| Ex vivo–expanded but not in vitro–induced human regulatory T cells are candidates for cell therapy in autoimmune diseases thanks to stable demethylation of the FOXP3 regulatory … M Rossetti, R Spreafico, S Saidin, C Chua, M Moshref, JY Leong, YK Tan, ... The Journal of Immunology 194 (1), 113-124, 2015 | 112 | 2015 |
| The controversial relationship between NLRP3, alum, danger signals and the next‐generation adjuvants R Spreafico, P Ricciardi‐Castagnoli, A Mortellaro European journal of immunology 40 (3), 638-642, 2010 | 112 | 2010 |
| IL-15 cis presentation is required for optimal NK cell activation in lipopolysaccharide-mediated inflammatory conditions I Zanoni, R Spreafico, C Bodio, M Di Gioia, C Cigni, A Broggi, T Gorletta, ... Cell reports 4 (6), 1235-1249, 2013 | 105 | 2013 |
| NF-κB dynamics determine the stimulus specificity of epigenomic reprogramming in macrophages QJ Cheng, S Ohta, KM Sheu, R Spreafico, A Adelaja, B Taylor, ... Science 372 (6548), 1349-1353, 2021 | 98 | 2021 |
| PGRMC2 is an intracellular haem chaperone critical for adipocyte function A Galmozzi, BP Kok, AS Kim, JR Montenegro-Burke, JY Lee, R Spreafico, ... Nature 576 (7785), 138-142, 2019 | 95 | 2019 |
| Increased autophagy in CD4+ T cells of rheumatoid arthritis patients results in T‐cell hyperactivation and apoptosis resistance J van Loosdregt, M Rossetti, R Spreafico, M Moshref, M Olmer, ... European journal of immunology 46 (12), 2862-2870, 2016 | 92 | 2016 |
Herbert W. VirginWashington University School of MedicineVerified email at wustl.edu
