A comparison of methods for the isolation and separation of extracellular vesicles from protein and lipid particles in human serum K Brennan, K Martin, SP FitzGerald, J O’sullivan, Y Wu, A Blanco, ... Scientific reports 10 (1), 1039, 2020 | 623 | 2020 |
Targeting the mitotic catastrophe signaling pathway in cancer MM Mc Gee Mediators of inflammation 2015, 2015 | 221 | 2015 |
Myc inhibition is effective against glioma and reveals a role for Myc in proficient mitosis D Annibali, JR Whitfield, E Favuzzi, T Jauset, E Serrano, I Cuartas, ... Nature communications 5 (1), 4632, 2014 | 205 | 2014 |
Caspase‐3 is not essential for DNA fragmentation in MCF‐7 cells during apoptosis induced by the pyrrolo‐1, 5‐benzoxazepine, PBOX‐6 MM Mc Gee, E Hyland, G Campiani, A Ramunno, V Nacci, DM Zisterer FEBS letters 515 (1-3), 66-70, 2002 | 124 | 2002 |
Death mechanisms in cultured cells infected by Semliki Forest virus GM Glasgow, MM McGee, BJ Sheahan, GJ Atkins Journal of General Virology 78 (7), 1559-1563, 1997 | 117 | 1997 |
The Semliki Forest virus vector induces p53-independent apoptosis GM Glasgow, MM McGee, CJ Tarbatt, DA Mooney, BJ Sheahan, GJ Atkins Journal of General Virology 79 (10), 2405-2410, 1998 | 102 | 1998 |
Substituted titanocenes induce caspase-dependent apoptosis in human epidermoid carcinoma cells in vitro and exhibit antitumour activity in vivo JH Bannon, I Fichtner, A O'Neill, C Pampillón, NJ Sweeney, K Strohfeldt, ... British journal of cancer 97 (9), 1234-1241, 2007 | 68 | 2007 |
Identification of tubulin as the molecular target of proapoptotic pyrrolo-1, 5-benzoxazepines JM Mulligan, LM Greene, S Cloonan, MM Mc Gee, V Onnis, G Campiani, ... Molecular Pharmacology 70 (1), 60-70, 2006 | 64 | 2006 |
Pyrrolo [1, 5] benzoxa (thia) zepines as a new class of potent apoptotic agents. Biological studies and identification of an intracellular location of their drug target MM Mc Gee, S Gemma, S Butini, A Ramunno, DM Zisterer, C Fattorusso, ... Journal of medicinal chemistry 48 (13), 4367-4377, 2005 | 54 | 2005 |
Activation of the c-Jun N-terminal kinase (JNK) signaling pathway is essential during PBOX-6-induced apoptosis in chronic myelogenous leukemia (CML) cells MM Mc Gee, G Campiani, A Ramunno, V Nacci, M Lawler, DC Williams, ... Journal of Biological Chemistry 277 (21), 18383-18389, 2002 | 51 | 2002 |
Recessive NEK9 mutation causes a lethal skeletal dysplasia with evidence of cell cycle and ciliary defects JP Casey, K Brennan, N Scheidel, P McGettigan, PT Lavin, S Carter, ... Human molecular genetics 25 (9), 1824-1835, 2016 | 50 | 2016 |
Mechanism of cell death mediated by a BF2‐chelated tetraaryl‐azadipyrromethene photodynamic therapeutic: Dissection of the apoptotic pathway in vitro and in vivo AE O'Connor, MM Mc Gee, Y Likar, V Ponomarev, JJ Callanan, DF O'shea, ... International journal of cancer 130 (3), 705-715, 2012 | 47 | 2012 |
The peptidyl prolyl isomerase cyclophilin A localizes at the centrosome and the midbody and is required for cytokinesis JH Bannon, DS o’Donovan, SME Kennelly, MM Mc Gee Cell Cycle 11 (7), 1340-1353, 2012 | 37 | 2012 |
Cyclin B1 interacts with the BH3-only protein Bim and mediates its phosphorylation by Cdk1 during mitosis S Mac Fhearraigh, MM Mc Gee Cell cycle 10 (22), 3886-3896, 2011 | 34 | 2011 |
Selective Induction of Apoptosis by the Pyrrolo-1, 5-benzoxazepine 7-[{Dimethylcarbamoyl} oxy]-6-(2-naphthyl) pyrrolo-[2, 1-d](1, 5)-benzoxazepine (PBOX-6) in Leukemia Cells … MM Mc Gee, LM Greene, S Ledwidge, G Campiani, V Nacci, M Lawler, ... Journal of Pharmacology and Experimental Therapeutics 310 (3), 1084-1095, 2004 | 34 | 2004 |
Pyrrolo-1, 5-benzoxazepines induce apoptosis in chronic myelogenous leukemia (CML) cells by bypassing the apoptotic suppressor bcr-abl MM Mc Gee, G Campiani, A Ramunno, C Fattorusso, V Nacci, M Lawler, ... Journal of Pharmacology and Experimental Therapeutics 296 (1), 31-40, 2001 | 33 | 2001 |
Understanding the role of aneuploidy in tumorigenesis JH Bannon, MM Mc Gee Biochemical society transactions 37 (4), 910-913, 2009 | 32 | 2009 |
Oxidative stress induces apoptosis in C6 glioma cells: involvement of mitogen-activated protein kinases and nuclear factor kappa B M Marangolo, MM McGee, KF Tipton, DC Williams, DM Zisterer Neurotoxicity research 3, 397-409, 2001 | 24 | 2001 |
Sequential Cdk1 and Plk1 phosphorylation of protein tyrosine phosphatase 1B promotes mitotic cell death DS O'donovan, S MacFhearraigh, J Whitfield, LB Swigart, GI Evan, ... Cell death & disease 4 (1), e468-e468, 2013 | 22 | 2013 |
Caspase-activated DNase (CAD)-independent oligonucleosomal DNA fragmentation in chronic myeloid leukaemia cells; a requirement for serine protease and Mn 2+-dependent acidic … LB McGrath, V Onnis, G Campiani, DC Williams, DM Zisterer, MM Mc Gee Apoptosis 11, 1473-1487, 2006 | 17 | 2006 |