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Michele Tonelli
Michele Tonelli
Associate Professor of Medicinal Chemistry, University of Genoa, Italy
Dirección de correo verificada de difar.unige.it
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Antiviral activity of benzimidazole derivatives. II. Antiviral activity of 2-phenylbenzimidazole derivatives
M Tonelli, M Simone, B Tasso, F Novelli, V Boido, F Sparatore, G Paglietti, ...
Bioorganic & medicinal chemistry 18 (8), 2937-2953, 2010
2362010
Antiviral and cytotoxic activities of aminoarylazo compounds and aryltriazene derivatives
M Tonelli, I Vazzana, B Tasso, V Boido, F Sparatore, M Fermeglia, ...
Bioorganic & medicinal chemistry 17 (13), 4425-4440, 2009
1182009
Antiviral activity of benzimidazole derivatives. I. Antiviral activity of 1‐substituted‐2‐[(benzotriazol‐1/2‐yl) methyl] benzimidazoles
M Tonelli, G Paglietti, V Boido, F Sparatore, F Marongiu, E Marongiu, ...
Chemistry & Biodiversity 5 (11), 2386-2401, 2008
942008
Quinolizidinyl derivatives of bi-and tricyclic systems as potent inhibitors of acetyl-and butyrylcholinesterase with potential in Alzheimer’s disease
B Tasso, M Catto, O Nicolotti, F Novelli, M Tonelli, I Giangreco, L Pisani, ...
European Journal of Medicinal Chemistry 46 (6), 2170-2184, 2011
872011
Antiviral activity of benzimidazole derivatives. III. Novel anti-CVB-5, anti-RSV and anti-Sb-1 agents
M Tonelli, F Novelli, B Tasso, I Vazzana, A Sparatore, V Boido, ...
Bioorganic & medicinal chemistry 22 (17), 4893-4909, 2014
862014
Acridine derivatives as anti-BVDV agents
M Tonelli, G Vettoretti, B Tasso, F Novelli, V Boido, F Sparatore, ...
Antiviral research 91 (2), 133-141, 2011
852011
Synthesis and biological evaluation of novel (thio) semicarbazone-based benzimidazoles as antiviral agents against human respiratory viruses
V Francesconi, E Cichero, S Schenone, L Naesens, M Tonelli
Molecules 25 (7), 1487, 2020
572020
Journey on naphthoquinone and anthraquinone derivatives: new insights in Alzheimer’s disease
M Campora, V Francesconi, S Schenone, B Tasso, M Tonelli
Pharmaceuticals 14 (1), 33, 2021
552021
Multitarget Therapeutic Leads for Alzheimer’s Disease: Quinolizidinyl Derivatives of Bi‐and Tricyclic Systems as Dual Inhibitors of Cholinesterases and β‐Amyloid (Aβ) Aggregation
M Tonelli, M Catto, B Tasso, F Novelli, C Canu, G Iusco, L Pisani, ...
ChemMedChem 10 (6), 1040-1053, 2015
532015
Benzimidazole derivatives endowed with potent antileishmanial activity
M Tonelli, E Gabriele, F Piazza, N Basilico, S Parapini, B Tasso, R Loddo, ...
Journal of Enzyme Inhibition and Medicinal Chemistry 33 (1), 210-226, 2018
452018
Novel biguanide-based derivatives scouted as TAAR1 agonists: Synthesis, biological evaluation, ADME prediction and molecular docking studies
M Tonelli, S Espinoza, RR Gainetdinov, E Cichero
European Journal of Medicinal Chemistry 127, 781-792, 2017
432017
Inhibition of chloride intracellular channel 1 (CLIC1) as biguanide class-effect to impair human glioblastoma stem cell viability
F Barbieri, R Würth, A Pattarozzi, I Verduci, C Mazzola, MG Cattaneo, ...
Frontiers in pharmacology 9, 899, 2018
412018
Pharmacophore modeling, resistant mutant isolation, docking, and MM-PBSA analysis: combined experimental/computer-assisted approaches to identify new inhibitors of the bovine …
M Tonelli, V Boido, P La Colla, R Loddo, P Posocco, MS Paneni, ...
Bioorganic & medicinal chemistry 18 (6), 2304-2316, 2010
402010
Rational design, chemical synthesis and biological evaluation of novel biguanides exploring species-specificity responsiveness of TAAR1 agonists
S Guariento, M Tonelli, S Espinoza, AS Gerasimov, RR Gainetdinov, ...
European journal of medicinal chemistry 146, 171-184, 2018
382018
Synergistic experimental/computational studies on arylazoenamine derivatives that target the bovine viral diarrhea virus RNA-dependent RNA polymerase
G Giliberti, C Ibba, E Marongiu, R Loddo, M Tonelli, V Boido, E Laurini, ...
Bioorganic & medicinal chemistry 18 (16), 6055-6068, 2010
372010
Efficacy of novel acridine derivatives in the inhibition of hPrP90-231 prion protein fragment toxicity
V Villa, M Tonelli, S Thellung, A Corsaro, B Tasso, F Novelli, C Canu, ...
Neurotoxicity research 19, 556-574, 2011
332011
Host dihydrofolate reductase (DHFR)-directed cycloguanil analogues endowed with activity against influenza virus and respiratory syncytial virus
M Tonelli, L Naesens, S Gazzarrini, M Santucci, E Cichero, B Tasso, ...
European Journal of Medicinal Chemistry 135, 467-478, 2017
302017
A homology modelling-driven study leading to the discovery of the first mouse trace amine-associated receptor 5 (TAAR5) antagonists
E Cichero, S Espinoza, M Tonelli, S Franchini, AS Gerasimov, C Sorbi, ...
MedChemComm 7 (2), 353-364, 2016
302016
Antimicrobial and cytotoxic arylazoenamines. Part III: antiviral activity of selected classes of arylazoenamines
M Tonelli, V Boido, C Canu, A Sparatore, F Sparatore, MS Paneni, ...
Bioorganic & medicinal chemistry 16 (18), 8447-8465, 2008
292008
Antiviral activity of benzotriazole derivatives. 5-[4-(Benzotriazol-2-yl) phenoxy]-2, 2-dimethylpentanoic acids potently and selectively inhibit Coxsackie Virus B5
R Loddo, F Novelli, A Sparatore, B Tasso, M Tonelli, V Boido, F Sparatore, ...
Bioorganic & medicinal chemistry 23 (21), 7024-7034, 2015
282015
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Artículos 1–20