Jules Hancox
Jules Hancox
Professor of Cardiac Electrophysiology, University of Bristol
Dirección de correo verificada de bristol.ac.uk - Página principal
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Cultured adult cardiac myocytes: future applications, culture methods, morphological and electrophysiological properties
JS Mitcheson, JC Hancox, AJ Levi
Cardiovascular research 39 (2), 280-300, 1998
Psychotropic drugs, cardiac arrhythmia, and sudden death
HJ Witchel, JC Hancox, DJ Nutt
Journal of clinical psychopharmacology 23 (1), 58-77, 2003
The hERG potassium channel and hERG screening for drug-induced torsades de pointes
JC Hancox, MJ McPate, A El Harchi, Y hong Zhang
Pharmacology & therapeutics 119 (2), 118-132, 2008
The concise guide to pharmacology 2017/18: overview
SPH Alexander, E Kelly, NV Marrion, JA Peters, E Faccenda, SD Harding, ...
British journal of pharmacology 174, S1-S16, 2017
The concise guide to PHARMACOLOGY 2015/16: Overview
SPH Alexander, E Kelly, N Marrion, JA Peters, HE Benson, E Faccenda, ...
British journal of pharmacology 172 (24), 5729-5743, 2015
Recent advances in understanding sex differences in cardiac repolarization
AF James, SCM Choisy, JC Hancox
Progress in biophysics and molecular biology 94 (3), 265-319, 2007
The Lambeth Conventions (II): guidelines for the study of animal and human ventricular and supraventricular arrhythmias
MJ Curtis, JC Hancox, A Farkas, CL Wainwright, CL Stables, DA Saint, ...
Pharmacology & therapeutics 139 (2), 213-248, 2013
Familial and acquired long QT syndrome and the cardiac rapid delayed rectifier potassium current
HJ Witchel, JC Hancox
Clinical and Experimental Pharmacology and Physiology 27 (10), 753-766, 2000
A new perspective in the field of cardiac safety testing through the comprehensive in vitro proarrhythmia assay paradigm
B Fermini, JC Hancox, N Abi-Gerges, M Bridgland-Taylor, KW Chaudhary, ...
Journal of biomolecular screening 21 (1), 1-11, 2016
Blockade of HERG potassium currents by fluvoxamine: incomplete attenuation by S6 mutations at F656 or Y652
JT Milnes, O Crociani, A Arcangeli, JC Hancox, HJ Witchel
British journal of pharmacology 139 (5), 887-898, 2003
VEGF-Mediated Elevated Intracellular Calcium and Angiogenesis in Human Microvascular Endothelial Cells In Vitro are Inhibited by Dominant Negative TRPC6
MA Hamdollah Zadeh, CA Glass, A Magnussen, JC Hancox, DO Bates
Microcirculation 15 (7), 605-614, 2008
Time course and voltage dependence of expressed HERG current compared with native” rapid” delayed rectifier K current during the cardiac ventricular action potential
JC Hancox, AJ Levi, HJ Witchel
Pflügers Archiv 436 (6), 843-853, 1998
Inhibition of the current of heterologously expressed HERG potassium channels by flecainide and comparison with quinidine, propafenone and lignocaine
AA Paul, HJ Witchel, JC Hancox
British journal of pharmacology 136 (5), 717-729, 2002
Inhibition of the current of heterologously expressed HERG potassium channels by imipramine and amitriptyline
AG Teschemacher, EP Seward, JC Hancox, HJ Witchel
British journal of pharmacology 128 (2), 479-485, 1999
Inhibitory actions of the selective serotonin re-uptake inhibitor citalopram on HERG and ventricular L-type calcium currents
HJ Witchel, VK Pabbathi, G Hofmann, AA Paul, JC Hancox
FEBS letters 512 (1-3), 59-66, 2002
KCNE5 (KCNE1L) Variants Are Novel Modulators of Brugada Syndrome and Idiopathic Ventricular Fibrillation
S Ohno, DP Zankov, WG Ding, H Itoh, T Makiyama, T Doi, S Shizuta, ...
Circulation: Arrhythmia and Electrophysiology 4 (3), 352-361, 2011
Troubleshooting problems with in vitro screening of drugs for QT interval prolongation using HERG K+ channels expressed in mammalian cell lines and Xenopus oocytes
HJ Witchel, JT Milnes, JS Mitcheson, JC Hancox
Journal of pharmacological and toxicological methods 48 (2), 65-80, 2002
VEGF activates receptor-operated cation channels in human microvascular endothelial cells
HW Cheng, AF James, RR Foster, JC Hancox, DO Bates
Arteriosclerosis, thrombosis, and vascular biology 26 (8), 1768-1776, 2006
The low-potency, voltage-dependent HERG blocker propafenone—molecular determinants and drug trapping
HJ Witchel, CE Dempsey, RB Sessions, M Perry, JT Milnes, JC Hancox, ...
Molecular pharmacology 66 (5), 1201-1212, 2004
The N588K-HERG K+ channel mutation in the ‘short QT syndrome’: mechanism of gain-in-function determined at 37 C
MJ McPate, RS Duncan, JT Milnes, HJ Witchel, JC Hancox
Biochemical and biophysical research communications 334 (2), 441-449, 2005
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Artículos 1–20