| TSC–mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species C Chen, Y Liu, R Liu, T Ikenoue, KL Guan, Y Liu, P Zheng The Journal of experimental medicine 205 (10), 2397-2408, 2008 | 759 | 2008 |
| A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity J Yang, W Wang, Z Chen, S Lu, F Yang, Z Bi, L Bao, F Mo, X Li, Y Huang, ... Nature 586 (7830), 572-577, 2020 | 719 | 2020 |
| mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells C Chen, Y Liu, Y Liu, P Zheng Science Signaling 2 (98), ra75, 2009 | 708 | 2009 |
| Safety and feasibility of CRISPR-edited T cells in patients with refractory non-small-cell lung cancer Y Lu, J Xue, T Deng, X Zhou, K Yu, L Deng, M Huang, X Yi, M Liang, ... Nature medicine 26 (5), 732-740, 2020 | 438 | 2020 |
| MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia C Chen, Y Liu, AR Rappaport, T Kitzing, N Schultz, Z Zhao, AS Shroff, ... Cancer cell 25 (5), 652-665, 2014 | 339 | 2014 |
| An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance J Zuber, AR Rappaport, W Luo, E Wang, C Chen, AV Vaseva, J Shi, ... Genes & Development 25 (15), 1628-1640, 2011 | 297 | 2011 |
| Deletions linked to TP53 loss drive cancer through p53-independent mechanisms Y Liu, C Chen, Z Xu, C Scuoppo, CD Rillahan, J Gao, B Spitzer, ... Nature 531 (7595), 471-475, 2016 | 264 | 2016 |
| Somatic single hits inactivate the X-linked tumor suppressor FOXP3 in the prostate L Wang, R Liu, W Li, C Chen, H Katoh, GY Chen, B McNally, L Lin, P Zhou, ... Cancer cell 16 (4), 336-346, 2009 | 261 | 2009 |
| Cancer-associated IDH2 mutants drive an acute myeloid leukemia that is susceptible to Brd4 inhibition C Chen, Y Liu, C Lu, JR Cross, JP Morris, AS Shroff, PS Ward, JE Bradner, ... Genes & development 27 (18), 1974-1985, 2013 | 214 | 2013 |
| Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction GY Chen, X Chen, S King, KA Cavassani, J Cheng, X Zheng, H Cao, H Yu, ... Nature biotechnology 29 (5), 428-435, 2011 | 193 | 2011 |
| Induction of sarcomas by mutant IDH2 C Lu, S Venneti, A Akalin, F Fang, PS Ward, RG DeMatteo, AM Intlekofer, ... Genes & development 27 (18), 1986-1998, 2013 | 180 | 2013 |
| Cutting edge: Broad expression of the FoxP3 locus in epithelial cells: a caution against early interpretation of fatal inflammatory diseases following in vivo depletion of … GY Chen, C Chen, L Wang, X Chang, P Zheng, Y Liu The Journal of Immunology 180 (8), 5163-5166, 2008 | 144 | 2008 |
| FOXP3 up-regulates p21 expression by site-specific inhibition of histone deacetylase 2/histone deacetylase 4 association to the locus R Liu, L Wang, G Chen, H Katoh, C Chen, Y Liu, P Zheng Cancer research 69 (6), 2252-2259, 2009 | 131 | 2009 |
| Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice C Chen, Y Liu, Y Liu, P Zheng The Journal of clinical investigation 120 (11), 4091-4101, 2010 | 125 | 2010 |
| Targeting the vascular and perivascular niches as a regenerative therapy for lung and liver fibrosis Z Cao, T Ye, Y Sun, G Ji, K Shido, Y Chen, L Luo, F Na, X Li, Z Huang, ... Science translational medicine 9 (405), eaai8710, 2017 | 103 | 2017 |
| An mTORC1-Mdm2-Drosha axis for miRNA biogenesis in response to glucose-and amino acid-deprivation P Ye, Y Liu, C Chen, F Tang, Q Wu, X Wang, CG Liu, X Liu, R Liu, Y Liu, ... Molecular cell 57 (4), 708-720, 2015 | 99 | 2015 |
| Nivolumab treatment of relapsed/refractory Epstein-Barr virus–associated hemophagocytic lymphohistiocytosis in adults P Liu, X Pan, C Chen, T Niu, X Shuai, J Wang, X Chen, J Liu, Y Guo, L Xie, ... Blood, The Journal of the American Society of Hematology 135 (11), 826-833, 2020 | 98 | 2020 |
| The tuberous sclerosis complex–mammalian target of rapamycin pathway maintains the quiescence and survival of naive T cells Q Wu, Y Liu, C Chen, T Ikenoue, Y Qiao, CS Li, W Li, KL Guan, Y Liu, ... The Journal of Immunology 187 (3), 1106-1112, 2011 | 90 | 2011 |
| CRISPR/Cas9-mediated genome editing of epigenetic factors for cancer therapy S Yao, Z He, C Chen Human gene therapy 26 (7), 463-471, 2015 | 71 | 2015 |
| The axis of mTOR-mitochondria-ROS and stemness of the hematopoietic stem cells C Chen, Y Liu, Y Liu, P Zheng Cell cycle 8 (8), 1158-1160, 2009 | 70 | 2009 |
Yu LiuSichuan UniversityDirección de correo verificada de scu.edu.cn
