| Importance of poly (ADP-ribose) polymerase and its cleavage in apoptosis Lesson from an uncleavable mutant FJ Oliver, G de la Rubia, V Rolli, MC Ruiz-Ruiz, G de Murcia, ... Journal of Biological Chemistry 273 (50), 33533-33539, 1998 | 935 | 1998 |
| ROS-induced DNA damage and PARP-1 are required for optimal induction of starvation-induced autophagy JM Rodríguez-Vargas, MJ Ruiz-Magaña, C Ruiz-Ruiz, ... Cell research 22 (7), 1181-1198, 2012 | 249 | 2012 |
| Doxorubicin induces apoptosis and CD95 gene expression in human primary endothelial cells through a p53-dependent mechanism E Lorenzo, C Ruiz-Ruiz, AJ Quesada, G Hernández, A Rodrı́guez, ... Journal of Biological Chemistry 277 (13), 10883-10892, 2002 | 193 | 2002 |
| Interferon-γ treatment elevates caspase-8 expression and sensitizes human breast tumor cells to a death receptor-induced mitochondria-operated apoptotic program C Ruiz-Ruiz, C Muñoz-Pinedo, A López-Rivas Cancer research 60 (20), 5673-5680, 2000 | 189 | 2000 |
| Inhibition of glucose metabolism sensitizes tumor cells to death receptor-triggered apoptosis through enhancement of death-inducing signaling complex formation and apical … C Muñoz-Pinedo, C Ruiz-Ruiz, CR de Almodóvar, C Palacios, ... Journal of Biological Chemistry 278 (15), 12759-12768, 2003 | 137 | 2003 |
| The up-regulation of human caspase-8 by interferon-γ in breast tumor cells requires the induction and action of the transcription factor interferon regulatory factor-1 C Ruiz-Ruiz, CR de Almodóvar, A Rodríguez, G Ortiz-Ferrón, ... Journal of Biological Chemistry 279 (19), 19712-19720, 2004 | 127 | 2004 |
| An exopolysaccharide produced by the novel halophilic bacterium Halomonas stenophila strain B100 selectively induces apoptosis in human T leukaemia cells C Ruiz-Ruiz, GK Srivastava, D Carranza, JA Mata, I Llamas, ... Applied microbiology and biotechnology 89 (2), 345-355, 2011 | 126 | 2011 |
| Perinatal derivatives: where do we stand? A roadmap of the human placenta and consensus for tissue and cell nomenclature AR Silini, R Di Pietro, I Lang-Olip, F Alviano, A Banerjee, M Basile, ... Frontiers in bioengineering and biotechnology, 1438, 2020 | 120 | 2020 |
| Reactive oxygen intermediate (s)(ROI): common mediator (s) of poly (ADP-ribose) polymerase (PARP) cleavage and apoptosis AJ McGowan, MC Ruiz-Ruiz, AM Gorman, A Lopez-Rivas, TG Cotter FEBS letters 392 (3), 299-303, 1996 | 118 | 1996 |
| GSK-3β inhibition by lithium confers resistance to chemotherapy-induced apoptosis through the repression of CD95 (Fas/APO-1) expression E Beurel, M Kornprobst, MJ Blivet-Van Eggelpoël, C Ruiz-Ruiz, A Cadoret, ... Experimental cell research 300 (2), 354-364, 2004 | 106 | 2004 |
| Mitochondria-dependent and-independent mechanisms in tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis are both regulated by interferon-γ in … RR Carmen, A López-Rivas Biochemical Journal 365 (3), 825-832, 2002 | 83 | 2002 |
| Interferon-γ sensitizes human myeloid leukemia cells to death receptor-mediated apoptosis by a pleiotropic mechanism N Varela, C Muñoz-Pinedo, C Ruiz-Ruiz, G Robledo, M Pedroso, ... Journal of Biological Chemistry 276 (21), 17779-17787, 2001 | 83 | 2001 |
| Protein kinase C inhibits CD95 (Fas/APO-1)-mediated apoptosis by at least two different mechanisms in Jurkat T cells C Ruiz-Ruiz, G Robledo, J Font, M Izquierdo, A López-Rivas The Journal of Immunology 163 (9), 4737-4746, 1999 | 82 | 1999 |
| p53-mediated up-regulation of CD95 is not involved in genotoxic drug-induced apoptosis of human breast tumor cells M del Carmen Ruiz-Ruiz, A López-Rivas Cell death and differentiation 6 (3), 271, 1999 | 69 | 1999 |
| Activation of protein kinase C attenuates early signals in Fas‐mediated apoptosis MDC Ruiz‐Ruiz, M Izquierdo, G de Murcia, A López‐Rivas European journal of immunology 27 (6), 1442-1450, 1997 | 66 | 1997 |
| The DNA methyltransferase inhibitors zebularine and decitabine induce mitochondria‐mediated apoptosis and DNA damage in p53 mutant leukemic T cells MJ Ruiz‐Magaña, JM Rodríguez‐Vargas, JC Morales, MA Saldivia, ... International journal of cancer 130 (5), 1195-1207, 2012 | 63 | 2012 |
| Activation of protein kinase C inhibits TRAIL-induced caspases activation, mitochondrial events and apoptosis in a human leukemic T cell line M Sarker, C Ruiz-Ruiz, A Lopez-Rivas Cell death and differentiation 8 (2), 172, 2001 | 62 | 2001 |
| The differential sensitivity of Bc1-2-overexpressing human breast tumor cells to TRAIL or doxorubicin-induced apoptosis is dependent on Bc1-2 protein levels CR de Almodóvar, C Ruiz-Ruiz, C Muñoz-Pinedo, G Robledo, ... Oncogene 20 (48), 7128, 2001 | 56 | 2001 |
| Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) decoy receptor TRAIL-R3 is up-regulated by p53 in breast tumor cells through a mechanism involving an intronic … CR de Almodóvar, C Ruiz-Ruiz, A Rodríguez, G Ortiz-Ferrón, ... Journal of Biological Chemistry 279 (6), 4093-4101, 2004 | 54 | 2004 |
| Characterization of p53-mediated up-regulation of CD95 gene expression upon genotoxic treatment in human breast tumor cells C Ruiz-Ruiz, G Robledo, E Cano, JM Redondo, A Lopez-Rivas Journal of Biological Chemistry 278 (34), 31667-31675, 2003 | 53 | 2003 |
