R loops: from transcription byproducts to threats to genome stability A Aguilera, T García-Muse Molecular cell 46 (2), 115-124, 2012 | 1128 | 2012 |
Replication stress and cancer H Gaillard, T García-Muse, A Aguilera Nature Reviews Cancer 15 (5), 276-289, 2015 | 1079 | 2015 |
TREX is a conserved complex coupling transcription with messenger RNA export K Sträßer, S Masuda, P Mason, J Pfannstiel, M Oppizzi, ... Nature 417 (6886), 304-308, 2002 | 1049 | 2002 |
Genome instability: a mechanistic view of its causes and consequences A Aguilera, B Gómez-González Nature Reviews Genetics 9 (3), 204-217, 2008 | 1009 | 2008 |
Cotranscriptionally formed DNA: RNA hybrids mediate transcription elongation impairment and transcription-associated recombination P Huertas, A Aguilera Molecular cell 12 (3), 711-721, 2003 | 879 | 2003 |
R loops: new modulators of genome dynamics and function JM Santos-Pereira, A Aguilera Nature Reviews Genetics 16 (10), 583-597, 2015 | 735 | 2015 |
Transcription-coupled nucleotide excision repair factors promote R-loop-induced genome instability J Sollier, CT Stork, ML García-Rubio, RD Paulsen, A Aguilera, ... Molecular cell 56 (6), 777-785, 2014 | 614 | 2014 |
CDK targets Sae2 to control DNA-end resection and homologous recombination P Huertas, F Cortés-Ledesma, AA Sartori, A Aguilera, SP Jackson Nature 455 (7213), 689-692, 2008 | 576 | 2008 |
Causes of genome instability A Aguilera, T García-Muse Annual review of genetics 47 (1), 1-32, 2013 | 560 | 2013 |
BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2 V Bhatia, SI Barroso, ML García-Rubio, E Tumini, E Herrera-Moyano, ... Nature 511 (7509), 362-365, 2014 | 553 | 2014 |
R loops: from physiological to pathological roles T García-Muse, A Aguilera Cell 179 (3), 604-618, 2019 | 504 | 2019 |
DNA repair in mammalian cells: DNA double-strand break repair: how to fix a broken relationship B Pardo, B Gómez-González, A Aguilera Cellular and Molecular Life Sciences 66, 1039-1056, 2009 | 495 | 2009 |
The connection between transcription and genomic instability A Aguilera The EMBO journal 21 (3), 195-201, 2002 | 423 | 2002 |
Yeast Sen1 helicase protects the genome from transcription-associated instability HE Mischo, B Gomez-Gonzalez, P Grzechnik, AG Rondon, W Wei, ... Molecular cell 41 (1), 21-32, 2011 | 410 | 2011 |
A protein complex containing Tho2, Hpr1, Mft1 and a novel protein, Thp2, connects transcription elongation with mitotic recombination in Saccharomyces cerevisiae S Chávez, T Beilharz, AG Rondón, H Erdjument‐Bromage, P Tempst, ... The EMBO journal, 2000 | 399 | 2000 |
Transcription–replication conflicts: how they occur and how they are resolved T García-Muse, A Aguilera Nature reviews Molecular cell biology 17 (9), 553-563, 2016 | 386 | 2016 |
Impairment of replication fork progression mediates RNA polII transcription‐associated recombination F Prado, A Aguilera The EMBO journal 24 (6), 1267-1276, 2005 | 368 | 2005 |
A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II HM Bourbon, A Aguilera, AZ Ansari, FJ Asturias, AJ Berk, S Bjorklund, ... Molecular cell 14 (5), 553-557, 2004 | 349 | 2004 |
The yeast THO complex and mRNA export factors link RNA metabolism with transcription and genome instability S Jimeno, AG Rondon, R Luna, A Aguilera The EMBO journal, 2002 | 330 | 2002 |
The Fanconi anemia pathway protects genome integrity from R-loops ML García-Rubio, C Pérez-Calero, SI Barroso, E Tumini, ... PLoS genetics 11 (11), e1005674, 2015 | 312 | 2015 |