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Benjamin Towler
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Mechanisms of regulation of mature miRNAs
BP Towler, CI Jones, SF Newbury
Biochemical Society Transactions 43 (6), 1208-1214, 2015
952015
Circulating microRNA biomarkers in melanoma: tools and challenges in personalised medicine
SL Mumford, BP Towler, AL Pashler, O Gilleard, Y Martin, SF Newbury
Biomolecules 8 (2), 21, 2018
722018
The roles of the exoribonucleases DIS3L2 and XRN1 in human disease
AL Pashler, BP Towler, CI Jones, SF Newbury
Biochemical Society Transactions 44 (5), 1377-1384, 2016
442016
The 3'-5'exoribonuclease Dis3 regulates the expression of specific microRNAs in Drosophila wing imaginal discs
BP Towler, CI Jones, SC Viegas, P Apura, JA Waldron, SK Smalley, ...
RNA biology 12 (7), 728-741, 2015
392015
Xrn1/Pacman affects apoptosis and regulates expression of hid and reaper
JA Waldron, CI Jones, BP Towler, AL Pashler, DP Grima, S Hebbes, ...
Biology open 4 (5), 649-660, 2015
322015
A novel role for the 3′-5′ exoribonuclease Dis3L2 in controlling cell proliferation and tissue growth
BP Towler, CI Jones, KL Harper, JA Waldron, SF Newbury
RNA biology 13 (12), 1286-1299, 2016
292016
RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease …
CI Jones, AL Pashler, BP Towler, SR Robinson, SF Newbury
Nucleic acids research 44 (1), 267-280, 2016
242016
Dis3L2 regulates cell proliferation and tissue growth through a conserved mechanism
BP Towler, AL Pashler, HJ Haime, KM Przybyl, SC Viegas, RG Matos, ...
PLoS genetics 16 (12), e1009297, 2020
152020
Regulation of cytoplasmic RNA stability: Lessons from Drosophila
BP Towler, SF Newbury
Wiley Interdisciplinary Reviews: RNA 9 (6), e1499, 2018
142018
Elucidation of focal adhesion kinase as a modulator of migration and invasion and as a potential therapeutic target in chronic lymphocytic leukemia
TA Burley, A Hesketh, G Bucca, E Kennedy, EE Ladikou, BP Towler, ...
Cancers 14 (7), 1600, 2022
72022
Genome-wide analyses of XRN1-sensitive targets in osteosarcoma cells identify disease-relevant transcripts containing G-rich motifs
AL Pashler, BP Towler, CI Jones, HJ Haime, T Burgess, SF Newbury
Rna 27 (10), 1265-1280, 2021
32021
Dis3L2 regulates cellular proliferation through a PI3-Kinase dependent signalling pathway
BP Towler, AL Pashler, HJ Haime, KM Przybyl, SC Viegas, RG Matos, ...
bioRxiv, 806109, 2019
12019
Characterisation of the in-vivo miRNA landscape in Drosophila ribonuclease mutants reveals Pacman-mediated regulation of the highly conserved let-7 cluster during apoptotic …
EIM Bernard, BP Towler, SF Newbury
Frontiers in Genetics 15, 1272689, 2024
2024
A β-catenin: MSI2 axis regulates the expression of LEF1 and subsequent human haematopoietic stem/progenitor cell proliferation
RG Morgan, M Wagstaff, DT Nguyen, A Blair, BP Towler, SF Newbury
bioRxiv, 2024.01. 28.577638, 2024
2024
The role of non-coding RNAs in extracellular vesicles in breast cancer and their diagnostic implications
M Samuels, W Jones, B Towler, C Turner, S Robinson, G Giamas
Oncogene 42 (41), 3017-3034, 2023
2023
Purriato is a conserved small open reading frame gene that interacts with the CASA pathway to regulate muscle homeostasis and epithelial tissue growth in Drosophila
JI Pueyo, J Salazar, C Grincho, J Berni, BP Towler, SF Newbury
Frontiers in Cell and Developmental Biology 11, 1117454, 2023
2023
USING TRANSCRIPTOMICS TO INVESTIGATE THE EFFECTS OF MILD INFLAMMATION IN MYALGIC ENCEPHALOMYELITIS/CHRONIC FATIGUE SYNDROME (ME/CFS) AND FIBROMYALGIA (FM)
ML Amato, BP Towler, K Themelis, KA Davies, S Newbury, JA Eccles, ...
PSYCHOSOMATIC MEDICINE 84 (5), A110-A111, 2022
2022
Genome-wide analyses of XRN1-sensitive targets in osteosarcoma cells identifies disease-relevant transcripts containing G-rich motifs
AL Pashler, BP Towler, CI Jones, T Burgess, SF Newbury
bioRxiv, 2020.08. 11.246249, 2020
2020
The Role of 3'-5'Exoribonucleases in Growth and Development of Drosophila Melanogaster
BP Towler
University of Brighton, 2016
2016
Regulation of Cytoplasmic RNA Stability: Lessons from
BP Towler, F Sarah
Nucleic Acids Res 42 (8), 5217-5233, 2014
2014
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