The Hippo pathway effector YAP controls mouse hepatic stellate cell activation I Mannaerts, SB Leite, S Verhulst, S Claerhout, N Eysackers, LFR Thoen, ... Journal of hepatology 63 (3), 679-688, 2015 | 347 | 2015 |
Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice IM Moya, SA Castaldo, L Van den Mooter, S Soheily, L Sansores-Garcia, ... Science 366 (6468), 1029-1034, 2019 | 154 | 2019 |
Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche O Govaere, J Wouters, M Petz, YP Vandewynckel, K Van den Eynde, ... Journal of hepatology 64 (3), 609-617, 2016 | 129 | 2016 |
Reactive cholangiocytes differentiate into proliferative hepatocytes with efficient DNA repair in mice with chronic liver injury R Manco, LA Clerbaux, S Verhulst, MB Nader, C Sempoux, J Ambroise, ... Journal of hepatology 70 (6), 1180-1191, 2019 | 67 | 2019 |
Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells A El Taghdouini, AL Sørensen, AH Reiner, M Coll, S Verhulst, I Mannaerts, ... Oncotarget 6 (29), 26729, 2015 | 67 | 2015 |
Circulating ECV-associated miRNAs as potential clinical biomarkers in early stage HBV and HCV induced liver fibrosis J Lambrecht, P Jan Poortmans, S Verhulst, H Reynaert, I Mannaerts, ... Frontiers in pharmacology 8, 56, 2017 | 58 | 2017 |
Prospects in non-invasive assessment of liver fibrosis: Liquid biopsy as the future gold standard? J Lambrecht, S Verhulst, I Mannaerts, H Reynaert, LA van Grunsven Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (4 …, 2018 | 54 | 2018 |
Gene expression profiling of early hepatic stellate cell activation reveals a role for Igfbp3 in cell migration I Mannaerts, B Schroyen, S Verhulst, L Van Lommel, F Schuit, M Nyssen, ... PloS one 8 (12), e84071, 2013 | 50 | 2013 |
Regeneration defects in Yap and Taz mutant mouse livers are caused by bile duct disruption and cholestasis E Verboven, IM Moya, L Sansores-Garcia, J Xie, H Hillen, W Kowalczyk, ... Gastroenterology 160 (3), 847-862, 2021 | 42 | 2021 |
Single cell RNA sequencing analysis did not predict hepatocyte infection by SARS-CoV-2 V De Smet, S Verhulst, LA van Grunsven Journal of hepatology 73 (4), 993-995, 2020 | 41 | 2020 |
Hippo signaling instructs ectopic but not normal organ growth W Kowalczyk, L Romanelli, M Atkins, H Hillen, C Bravo González-Blas, ... Science 378 (6621), eabg3679, 2022 | 34 | 2022 |
A PDGFRβ-based score predicts significant liver fibrosis in patients with chronic alcohol abuse, NAFLD and viral liver disease J Lambrecht, S Verhulst, I Mannaerts, JP Sowa, J Best, A Canbay, ... EBioMedicine 43, 501-512, 2019 | 32 | 2019 |
Macrophage depletion attenuates extracellular matrix deposition and ductular reaction in a mouse model of chronic cholangiopathies J Best, S Verhulst, WK Syn, K Lagaisse, N van Hul, F Heindryckx, ... Plos one 11 (9), e0162286, 2016 | 32 | 2016 |
Loss of RASSF4 expression in multiple myeloma promotes RAS-driven malignant progression E De Smedt, K Maes, S Verhulst, H Lui, A Kassambara, A Maes, N Robert, ... Cancer research 78 (5), 1155-1168, 2018 | 30 | 2018 |
Directed differentiation of human induced pluripotent stem cells to hepatic stellate cells J Vallverdú, RA Martinez Garcia de la Torre, I Mannaerts, S Verhulst, ... Nature Protocols 16 (5), 2542-2563, 2021 | 29 | 2021 |
Advances in hepatic stem/progenitor cell biology S Verhulst, J Best, LA van Grunsven, L Dollé EXCLI journal 14, 33, 2015 | 29 | 2015 |
Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis W de Haan, W Dheedene, K Apelt, S Decombas-Deschamps, S Vinckier, ... Cardiovascular research 118 (5), 1262-1275, 2022 | 27 | 2022 |
The fibrotic response of primary liver spheroids recapitulates in vivo hepatic stellate cell activation I Mannaerts, N Eysackers, EA van Os, S Verhulst, T Roosens, A Smout, ... Biomaterials 261, 120335, 2020 | 27 | 2020 |
The miRFIB-score: a serological miRNA-based scoring algorithm for the diagnosis of significant liver fibrosis J Lambrecht, S Verhulst, H Reynaert, LA van Grunsven Cells 8 (9), 1003, 2019 | 26 | 2019 |
PU. 1 drives specification of pluripotent stem cell-derived endothelial cells to LSEC-like cells J De Smedt, EA van Os, I Talon, S Ghosh, B Toprakhisar, ... Cell death & disease 12 (1), 84, 2021 | 25 | 2021 |