Follow
Bartholomew P. Roland
Bartholomew P. Roland
Septerna Inc.
Verified email at septerna.com
Title
Cited by
Cited by
Year
Genetically engineered mesenchymal stem cells reduce behavioral deficits in the YAC 128 mouse model of Huntington's disease
ND Dey, MC Bombard, BP Roland, S Davidson, M Lu, J Rossignol, ...
Behavioural brain research 214 (2), 193-200, 2010
1822010
Inhibiting the nucleation of amyloid structure in a huntingtin fragment by targeting α-helix-rich oligomeric intermediates
R Mishra, M Jayaraman, BP Roland, E Landrum, T Fullam, R Kodali, ...
Journal of molecular biology 415 (5), 900-917, 2012
892012
Yeast and human P4-ATPases transport glycosphingolipids using conserved structural motifs
BP Roland, T Naito, JT Best, C Arnaiz-Yépez, H Takatsu, JY Roger, ...
Journal of Biological Chemistry 294 (6), 1794-1806, 2019
612019
Mechanisms of endothelial cell dysfunction in cystic fibrosis
L Totani, R Plebani, A Piccoli, S Di Silvestre, P Lanuti, A Recchiuti, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (12 …, 2017
582017
A tutorial for pharmacogenomics implementation through end‐to‐end clinical decision support based on ten years of experience from PREDICT
M Liu, CL Vnencak‐Jones, BP Roland, CL Gatto, JL Mathe, SL Just, ...
Clinical Pharmacology & Therapeutics 109 (1), 101-115, 2021
392021
Decoding P4-ATPase substrate interactions
BP Roland, TR Graham
Critical reviews in biochemistry and molecular biology 51 (6), 513-527, 2016
392016
Evidence of a triosephosphate isomerase non-catalytic function crucial to behavior and longevity
BP Roland, KA Stuchul, SB Larsen, CG Amrich, AP VanDemark, ...
Journal of Cell Science 126 (14), 3151-3158, 2013
392013
Adaptive substitutions underlying cardiac glycoside insensitivity in insects exhibit epistasis in vivo
AM Taverner, L Yang, ZJ Barile, B Lin, J Peng, AP Pinharanda, AS Rao, ...
Elife 8, e48224, 2019
382019
Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency
BP Roland, CG Amrich, CJ Kammerer, KA Stuchul, SB Larsen, S Rode, ...
Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (1), 61-69, 2015
362015
Structural and genetic studies demonstrate neurologic dysfunction in triosephosphate isomerase deficiency is associated with impaired synaptic vesicle dynamics
BP Roland, AM Zeccola, SB Larsen, CG Amrich, AD Talsma, KA Stuchul, ...
PLoS Genetics 12 (3), e1005941, 2016
312016
Directed evolution of a sphingomyelin flippase reveals mechanism of substrate backbone discrimination by a P4-ATPase
BP Roland, TR Graham
Proceedings of the National Academy of Sciences 113 (31), E4460-E4466, 2016
252016
A serendipitous survey of prediction algorithms for amyloidogenicity
BP Roland, R Kodali, R Mishra, R Wetzel
Peptide Science 100 (6), 780-789, 2013
222013
Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo
BP Roland, KR Richards, SL Hrizo, S Eicher, ZJ Barile, TC Chang, ...
Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease 1865 (9 …, 2019
172019
Exofacial membrane composition and lipid metabolism regulates plasma membrane P4-ATPase substrate specificity
BK Jain, BP Roland, TR Graham
Journal of Biological Chemistry 295 (52), 17997-18009, 2020
82020
Impact of updating pharmacogenetic results: lessons learned from the PREDICT program
M Liu, SL Van Driest, CL Vnencak-Jones, LAG Saucier, BP Roland, ...
Journal of Personalized Medicine 11 (11), 1051, 2021
62021
The novel neuroimmunophillin, GPI 1485, attenuates age-related cognitive deficits in rats
ND Dey, MC Bombard, RA Myers, AJ Boersen, BP Roland, MI Sandstrom, ...
CELL TRANSPLANTATION 16 (3), 319-320, 2007
32007
Exofacial membrane composition and lipid metabolism regulates plasma membrane P4-ATPase substrate specificity
BP Roland, BK Jain, TR Graham
bioRxiv, 2020.06. 24.169672, 2020
22020
Intrastriatal transplantation of bone marrow stem cells that are genetically engineered to overexpress brain-derived neurotrophic factor reduces behavioral deficits in the …
MC Bombard, ND Dey, BP Roland, M Lu, J Matchynski, S Lowrance, ...
CELL TRANSPLANTATION 17 (4), 462-462, 2008
22008
Predatory fireflies and their toxic firefly prey have evolved distinct toxin resistance strategies
L Yang, F Borne, A Betz, ML Aardema, Y Zhen, J Peng, R Visconti, M Wu, ...
Current Biology 33 (23), 5160-5168. e7, 2023
12023
A Tutorial for Pharmacogenomics Implementation Through End-to-End Clinical Decision Support Based on Ten Years of Experience From PREDICT (vol 109, pg 101, 2021)
M Liu, CL Vnencak-Jones, BP Roland, CL Gatto, JL Mathe, SL Just, ...
CLINICAL PHARMACOLOGY & THERAPEUTICS 112 (5), 1130-1130, 2022
2022
The system can't perform the operation now. Try again later.
Articles 1–20