Jason Locasale
Jason Locasale
Duke University
Verified email at - Homepage
Cited by
Cited by
The Warburg effect: how does it benefit cancer cells?
MV Liberti, JW Locasale
Trends in biochemical sciences 41 (3), 211-218, 2016
Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism
H Ying, AC Kimmelman, CA Lyssiotis, S Hua, GC Chu, ...
Cell 149 (3), 656-670, 2012
Serine, glycine and one-carbon units: cancer metabolism in full circle
JW Locasale
Nature Reviews Cancer 13 (8), 572-583, 2013
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses
D Anastasiou, G Poulogiannis, JM Asara, MB Boxer, J Jiang, M Shen, ...
Science 334 (6060), 1278-1283, 2011
Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses
PC Ho, JD Bihuniak, AN Macintyre, M Staron, X Liu, R Amezquita, ...
Cell 162 (6), 1217-1228, 2015
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
JW Locasale, AR Grassian, T Melman, CA Lyssiotis, KR Mattaini, AJ Bass, ...
Nature genetics 43 (9), 869-874, 2011
Evidence for an alternative glycolytic pathway in rapidly proliferating cells
MG Vander Heiden, JW Locasale, KD Swanson, H Sharfi, GJ Heffron, ...
Science 329 (5998), 1492-1499, 2010
Influence of threonine metabolism on S-adenosylmethionine and histone methylation
N Shyh-Chang, JW Locasale, CA Lyssiotis, Y Zheng, RY Teo, ...
Science 339 (6116), 222-226, 2013
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
VA Gerriets, RJ Kishton, AG Nichols, AN Macintyre, M Inoue, O Ilkayeva, ...
The Journal of clinical investigation 125 (1), 194-207, 2015
A roadmap for interpreting 13C metabolite labeling patterns from cells
JM Buescher, MR Antoniewicz, LG Boros, SC Burgess, H Brunengraber, ...
Current opinion in biotechnology 34, 189-201, 2015
Histone methylation dynamics and gene regulation occur through the sensing of one-carbon metabolism
SJ Mentch, M Mehrmohamadi, L Huang, X Liu, D Gupta, D Mattocks, ...
Cell metabolism 22 (5), 861-873, 2015
Glutamine metabolism in cancer: understanding the heterogeneity
AA Cluntun, MJ Lukey, RA Cerione, JW Locasale
Trends in cancer 3 (3), 169-180, 2017
Metabolic flux and the regulation of mammalian cell growth
JW Locasale, LC Cantley
Cell metabolism 14 (4), 443-451, 2011
Distinct regulation of Th17 and Th1 cell differentiation by glutaminase-dependent metabolism
MO Johnson, MM Wolf, MZ Madden, G Andrejeva, A Sugiura, ...
Cell 175 (7), 1780-1795. e19, 2018
Foxp3 and Toll-like receptor signaling balance Treg cell anabolic metabolism for suppression
VA Gerriets, RJ Kishton, MO Johnson, S Cohen, PJ Siska, AG Nichols, ...
Nature immunology 17 (12), 1459-1466, 2016
Dietary methionine influences therapy in mouse cancer models and alters human metabolism
X Gao, SM Sanderson, Z Dai, MA Reid, DE Cooper, M Lu, JP Richie Jr, ...
Nature 572 (7769), 397-401, 2019
Heterogeneity of tumor-induced gene expression changes in the human metabolic network
J Hu, JW Locasale, JH Bielas, J O'sullivan, K Sheahan, LC Cantley, ...
Nature biotechnology 31 (6), 522-529, 2013
The impact of cellular metabolism on chromatin dynamics and epigenetics
MA Reid, Z Dai, JW Locasale
Nature cell biology 19 (11), 1298-1306, 2017
Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
OG McDonald, X Li, T Saunders, R Tryggvadottir, SJ Mentch, ...
Nature genetics 49 (3), 367-376, 2017
Metabolomics: a primer
X Liu, JW Locasale
Trends in biochemical sciences 42 (4), 274-284, 2017
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