Strategies for the discovery and development of therapies for metastatic breast cancer BL Eckhardt, PA Francis, BS Parker, RL Anderson Nature reviews Drug discovery 11 (6), 479-497, 2012 | 374 | 2012 |
Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix BL Eckhardt, BS Parker, RK Van Laar, CM Restall, AL Natoli, MD Tavaria, ... Molecular Cancer Research 3 (1), 1-13, 2005 | 296 | 2005 |
Functional and molecular characterisation of EO771. LMB tumours, a new C57BL/6-mouse-derived model of spontaneously metastatic mammary cancer CN Johnstone, YE Smith, Y Cao, AD Burrows, RSN Cross, X Ling, ... Disease models & mechanisms 8 (3), 237-251, 2015 | 271 | 2015 |
Is the future of personalized therapy in triple-negative breast cancer based on molecular subtype? F Le Du, BL Eckhardt, B Lim, JK Litton, S Moulder, F Meric-Bernstam, ... Oncotarget 6 (15), 12890, 2015 | 143 | 2015 |
BMP4 inhibits breast cancer metastasis by blocking myeloid-derived suppressor cell activity Y Cao, CY Slaney, BN Bidwell, BS Parker, CN Johnstone, J Rautela, ... Cancer research 74 (18), 5091-5102, 2014 | 127 | 2014 |
Targeting neuropilin-1 in human leukemia and lymphoma K Karjalainen, DE Jaalouk, CE Bueso-Ramos, AJ Zurita, A Kuniyasu, ... Blood, The Journal of the American Society of Hematology 117 (3), 920-927, 2011 | 125 | 2011 |
Inhibition of established micrometastases by targeted drug delivery via cell surface–associated GRP78 YR Miao, BL Eckhardt, Y Cao, R Pasqualini, P Argani, W Arap, ... Clinical cancer research 19 (8), 2107-2116, 2013 | 96 | 2013 |
Primary tumour expression of the cysteine cathepsin inhibitor Stefin A inhibits distant metastasis in breast cancer BS Parker, DR Ciocca, BN Bidwell, FE Gago, MA Fanelli, J George, ... The Journal of pathology 214 (3), 337-346, 2008 | 79 | 2008 |
Metallothionein-III inhibits initial neurite formation in developing neurons as well as postinjury, regenerative neurite sprouting RS Chung, JC Vickers, MI Chuah, BL Eckhardt, AK West Experimental neurology 178 (1), 1-12, 2002 | 64 | 2002 |
2-methoxyestradiol is an estrogen receptor agonist that supports tumor growth in murine xenograft models of breast cancer TE Sutherland, M Schuliga, T Harris, BL Eckhardt, RL Anderson, L Quan, ... Clinical cancer research 11 (5), 1722-1732, 2005 | 59 | 2005 |
Activation of canonical BMP4-SMAD7 signaling suppresses breast cancer metastasis BL Eckhardt, Y Cao, AD Redfern, LH Chi, AD Burrows, S Roslan, ... Cancer research 80 (6), 1304-1315, 2020 | 49 | 2020 |
EGFR signaling promotes inflammation and cancer stem-like activity in inflammatory breast cancer X Wang, ME Reyes, D Zhang, Y Funakoshi, AP Trape, Y Gong, T Kogawa, ... Oncotarget 8 (40), 67904, 2017 | 47 | 2017 |
Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux AM Torres-Adorno, H Vitrac, Y Qi, L Tan, KR Levental, YY Fan, P Yang, ... Oncogene 38 (12), 2135-2150, 2019 | 39 | 2019 |
Poor prognosis of patients with triple-negative breast cancer can be stratified by RANK and RANKL dual expression ME Reyes, T Fujii, D Branstetter, S Krishnamurthy, H Masuda, X Wang, ... Breast cancer research and treatment 164, 57-67, 2017 | 38 | 2017 |
Towards a transcriptome-based theranostic platform for unfavorable breast cancer phenotypes AS Dobroff, S D’Angelo, BL Eckhardt, F Ferrara, DI Staquicini, ... Proceedings of the National Academy of Sciences 113 (45), 12780-12785, 2016 | 36 | 2016 |
Nephronectin is correlated with poor prognosis in breast cancer and promotes metastasis via its integrin-binding motifs TS Steigedal, J Toraskar, RP Redvers, M Valla, SN Magnussen, AM Bofin, ... Neoplasia 20 (4), 387-400, 2018 | 34 | 2018 |
NDRG1 in aggressive breast cancer progression and brain metastasis ES Villodre, X Hu, BL Eckhardt, R Larson, L Huo, EC Yoon, Y Gong, ... JNCI: Journal of the National Cancer Institute 114 (4), 579-591, 2022 | 29 | 2022 |
Sheep have an unusual variant of the brain-specific metallothionein, metallothionein-III RS Chung, AF Holloway, BL Eckhardt, JA Harris, JC Vickers, MI Chuah, ... Biochemical Journal 365 (1), 323-328, 2002 | 25 | 2002 |
Targeting a cell surface vitamin D receptor on tumor-associated macrophages in triple-negative breast cancer FI Staquicini, A Hajitou, WHP Driessen, B Proneth, M Cardó-Vila, ... Elife 10, e65145, 2021 | 22 | 2021 |
Identification of triple-negative breast cancer cell lines classified under the same molecular subtype using different molecular characterization techniques: Implications for … JR Espinosa Fernandez, BL Eckhardt, J Lee, B Lim, T Pearson, RS Seitz, ... PLoS One 15 (4), e0231953, 2020 | 22 | 2020 |