New potentiators of ineffective antibiotics: Targeting the Gram-negative outer membrane to overcome intrinsic resistance K Klobucar, ED Brown Current Opinion in Chemical Biology 66, 102099, 2022 | 44 | 2022 |
Chemical screen for vancomycin antagonism uncovers probes of the gram-negative outer membrane K Klobucar, JP Côté, S French, L Borrillo, ABY Guo, MH Serrano-Wu, ... ACS Chemical Biology 16 (5), 929-942, 2021 | 38 | 2021 |
Genetic and chemical-genetic interactions map biogenesis and permeability determinants of the outer membrane of Escherichia coli K Klobucar, S French, JP Côté, JR Howes, ED Brown MBio 11 (2), 10.1128/mbio. 00161-20, 2020 | 27 | 2020 |
Use of genetic and chemical synthetic lethality as probes of complexity in bacterial cell systems K Klobucar, ED Brown FEMS Microbiology Reviews 42 (1), fux054, 2018 | 23 | 2018 |
Kaiso differentially regulates components of the Notch signaling pathway in intestinal cells SC Robinson, K Klobucar, CC Pierre, A Ansari, S Zhenilo, ... Cell Communication and Signaling 15, 1-13, 2017 | 21 | 2017 |
Genetic and chemical screening reveals targets and compounds to potentiate gram-positive antibiotics against gram-negative bacteria K Klobucar, E Jardine, MA Farha, MR MacKinnon, M Fragis, B Nkonge, ... ACS Infectious Diseases 8 (10), 2187-2197, 2022 | 7 | 2022 |
Polynuclear ruthenium complexes are effective antibiotics against Pseudomonas aeruginosa BS Weber, LA Carfrae, JJ Woods, K Klobucar, NP Bigham, CR MacNair, ... bioRxiv, 2022.08. 11.503708, 2022 | 1 | 2022 |
Genetic and Chemical Targeting of the Gram-Negative Outer Membrane to Potentiate Large-Scaffold Antibiotics K Klobucar | | 2022 |