| Elucidation of thioredoxin as a molecular target for antitumor quinols TD Bradshaw, CS Matthews, J Cookson, EH Chew, M Shah, K Bailey, ... Cancer research 65 (9), 3911-3919, 2005 | 113 | 2005 |
| Crystal structure of a cytochrome P450 2B6 genetic variant in complex with the inhibitor 4-(4-chlorophenyl) imidazole at 2.0-Å resolution SC Gay, MB Shah, JC Talakad, K Maekawa, AG Roberts, PR Wilderman, ... Molecular pharmacology 77 (4), 529-538, 2010 | 105 | 2010 |
| The 1.8 Å crystal structure of PA2412, an MbtH-like protein from the pyoverdine cluster of Pseudomonas aeruginosa EJ Drake, J Cao, J Qu, MB Shah, RM Straubinger, AM Gulick Journal of Biological Chemistry 282 (28), 20425-20434, 2007 | 88 | 2007 |
| Conformational adaptation of human cytochrome P450 2B6 and rabbit cytochrome P450 2B4 revealed upon binding multiple amlodipine molecules MB Shah, PR Wilderman, J Pascual, Q Zhang, CD Stout, JR Halpert Biochemistry 51 (37), 7225-7238, 2012 | 76 | 2012 |
| Plasticity of cytochrome P450 2B4 as investigated by hydrogen-deuterium exchange mass spectrometry and X-ray crystallography PR Wilderman, MB Shah, T Liu, S Li, S Hsu, AG Roberts, DR Goodlett, ... Journal of Biological Chemistry 285 (49), 38602-38611, 2010 | 62 | 2010 |
| Halogen− π interactions in the cytochrome P450 active site: Structural insights into human CYP2B6 substrate selectivity MB Shah, J Liu, Q Zhang, CD Stout, JR Halpert ACS chemical biology 12 (5), 1204-1210, 2017 | 52 | 2017 |
| Structural Basis of Single-Nucleotide Polymorphisms in Cytochrome P450 2C9 K Maekawa, M Adachi, Y Matsuzawa, Q Zhang, R Kuroki, Y Saito, ... Biochemistry 56 (41), 5476–5480, 2017 | 49 | 2017 |
| Structures of cytochrome P450 2B6 bound to 4-benzylpyridine and 4-(4-nitrobenzyl) pyridine: insight into inhibitor binding and rearrangement of active site side chains MB Shah, J Pascual, Q Zhang, CD Stout, JR Halpert Molecular pharmacology 80 (6), 1047-1055, 2011 | 49 | 2011 |
| Structural and thermodynamic basis of (+)-α-pinene binding to human cytochrome P450 2B6 PR Wilderman, MB Shah, HH Jang, CD Stout, JR Halpert Journal of the American Chemical Society 135 (28), 10433-10440, 2013 | 41 | 2013 |
| Potent mechanism-based inactivation of cytochrome P450 2B4 by 9-ethynylphenanthrene: implications for allosteric modulation of cytochrome P450 catalysis H Zhang, SC Gay, M Shah, M Foroozesh, J Liu, Y Osawa, Q Zhang, ... Biochemistry 52 (2), 355-364, 2013 | 29 | 2013 |
| The 2.1 Å crystal structure of an acyl‐CoA synthetase from Methanosarcina acetivorans reveals an alternate acyl‐binding pocket for small branched acyl substrates MB Shah, C Ingram‐Smith, LL Cooper, J Qu, Y Meng, KS Smith, ... Proteins: Structure, Function, and Bioinformatics 77 (3), 685-698, 2009 | 27 | 2009 |
| Comparison of in vitro metabolism of ticlopidine by human cytochrome P450 2B6 and rabbit cytochrome P450 2B4 JC Talakad, MB Shah, GS Walker, C Xiang, JR Halpert, D Dalvie Drug metabolism and disposition 39 (3), 539-550, 2011 | 25 | 2011 |
| Structural and biophysical characterization of human cytochromes P450 2B6 and 2A6 bound to volatile hydrocarbons: analysis and comparison MB Shah, PR Wilderman, J Liu, HH Jang, Q Zhang, CD Stout, JR Halpert Molecular pharmacology 87 (4), 649-659, 2015 | 22 | 2015 |
| Structure of Mycobacterium tuberculosis thioredoxin C G Hall, M Shah, PA McEwan, C Laughton, M Stevens, A Westwell, ... Acta Crystallographica Section D: Biological Crystallography 62 (12), 1453-1457, 2006 | 22 | 2006 |
| Structure-function analysis of mammalian CYP2B enzymes using 7-substituted coumarin derivatives as probes: utility of crystal structures and molecular modeling in understanding … MB Shah, J Liu, L Huo, Q Zhang, MD Dearing, PR Wilderman, GD Szklarz, ... Molecular Pharmacology 89 (4), 435-445, 2016 | 17 | 2016 |
| A structural snapshot of CYP2B4 in complex with paroxetine provides insights into ligand binding and clusters of conformational states MB Shah, I Kufareva, J Pascual, Q Zhang, CD Stout, JR Halpert Journal of Pharmacology and Experimental Therapeutics 346 (1), 113-120, 2013 | 16 | 2013 |
| Structure of cytochrome P450 2C9* 2 in complex with losartan: insights into the effect of genetic polymorphism SJ Parikh, CM Evans, JO Obi, Q Zhang, K Maekawa, KC Glass, MB Shah Molecular pharmacology 98 (5), 529-539, 2020 | 15 | 2020 |
| Coumarin derivatives as substrate probes of mammalian cytochromes P450 2B4 and 2B6: assessing the importance of 7-alkoxy chain length, halogen substitution, and non-active site … J Liu, MB Shah, Q Zhang, CD Stout, JR Halpert, PR Wilderman Biochemistry 55 (13), 1997-2007, 2016 | 13 | 2016 |
| X-ray crystal structure of the cytochrome P450 2B4 active site mutant F297A in complex with clopidogrel: insights into compensatory rearrangements of the binding pocket MB Shah, HH Jang, Q Zhang, CD Stout, JR Halpert Archives of biochemistry and biophysics 530 (2), 64-72, 2013 | 12 | 2013 |
| Effect of detergent binding on cytochrome P450 2B4 structure as analyzed by X-ray crystallography and deuterium-exchange mass spectrometry MB Shah, HH Jang, PR Wilderman, D Lee, S Li, Q Zhang, CD Stout, ... Biophysical chemistry 216, 1-8, 2016 | 11 | 2016 |
