Oscar Fernandez-Capetillo
Oscar Fernandez-Capetillo
Genomic Instability Group, Spanish National Cancer Research Centre (CNIO)
Dirección de correo verificada de cnio.es - Página principal
TítuloCitado porAño
Genomic instability in mice lacking histone H2AX
A Celeste, S Petersen, PJ Romanienko, O Fernandez-Capetillo, HT Chen, ...
Science 296 (5569), 922-927, 2002
13842002
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
A Celeste, O Fernandez-Capetillo, MJ Kruhlak, DR Pilch, DW Staudt, ...
Nature cell biology 5 (7), 675, 2003
10312003
H2AX: the histone guardian of the genome
O Fernandez-Capetillo, A Lee, M Nussenzweig, A Nussenzweig
DNA repair 3 (8-9), 959-967, 2004
9982004
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
SF Bunting, E Callén, N Wong, HT Chen, F Polato, A Gunn, A Bothmer, ...
Cell 141 (2), 243-254, 2010
9812010
A p53-mediated DNA damage response limits reprogramming to ensure iPS cell genomic integrity
RM Marión, K Strati, H Li, M Murga, R Blanco, S Ortega, ...
Nature 460 (7259), 1149, 2009
9482009
DNA damage-induced G2–M checkpoint activation by histone H2AX and 53BP1
O Fernandez-Capetillo, HT Chen, A Celeste, I Ward, PJ Romanienko, ...
Nature cell biology 4 (12), 993, 2002
6702002
H2AX haploinsufficiency modifies genomic stability and tumor susceptibility
A Celeste, S Difilippantonio, MJ Difilippantonio, O Fernandez-Capetillo, ...
Cell 114 (3), 371-383, 2003
5612003
H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis
O Fernandez-Capetillo, SK Mahadevaiah, A Celeste, PJ Romanienko, ...
Developmental cell 4 (4), 497-508, 2003
4932003
Sirt1 improves healthy ageing and protects from metabolic syndrome-associated cancer
D Herranz, M Muñoz-Martin, M Cañamero, F Mulero, B Martinez-Pastor, ...
Nature communications 1, 3, 2010
4632010
Silencing of unsynapsed meiotic chromosomes in the mouse
JMA Turner, SK Mahadevaiah, O Fernandez-Capetillo, A Nussenzweig, ...
Nature genetics 37 (1), 41, 2005
4492005
Changes in chromatin structure and mobility in living cells at sites of DNA double-strand breaks
MJ Kruhlak, A Celeste, G Dellaire, O Fernandez-Capetillo, WG Müller, ...
J Cell Biol 172 (6), 823-834, 2006
4402006
A cell-based screen identifies ATR inhibitors with synthetic lethal properties for cancer-associated mutations
LI Toledo, M Murga, R Zur, R Soria, A Rodriguez, S Martinez, J Oyarzabal, ...
Nature structural & molecular biology 18 (6), 721, 2011
3222011
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice
P Martínez, M Thanasoula, P Muñoz, C Liao, A Tejera, C McNees, ...
Genes & development, 2009
2872009
Activation-induced cytidine deaminase targets DNA at sites of RNA polymerase II stalling by interaction with Spt5
R Pavri, A Gazumyan, M Jankovic, M Di Virgilio, I Klein, ...
Cell 143 (1), 122-133, 2010
2832010
A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging
M Murga, S Bunting, MF Montaña, R Soria, F Mulero, M Cañamero, Y Lee, ...
Nature genetics 41 (8), 891, 2009
2682009
Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models
S Difilippantonio, A Celeste, O Fernandez-Capetillo, HT Chen, ...
Nature cell biology 7 (7), 675, 2005
2472005
ATM regulates ATR chromatin loading in response to DNA double-strand breaks
M Cuadrado, B Martinez-Pastor, M Murga, LI Toledo, P Gutierrez-Martinez, ...
Journal of Experimental Medicine 203 (2), 297-303, 2006
2362006
Identification of early replicating fragile sites that contribute to genome instability
JH Barlow, RB Faryabi, E Callén, N Wong, A Malhowski, HT Chen, ...
Cell 152 (3), 620-632, 2013
2322013
Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors
M Murga, S Campaner, AJ Lopez-Contreras, LI Toledo, R Soria, ...
Nature structural & molecular biology 18 (12), 1331, 2011
2312011
Focusing on foci: H2AX and the recruitment of DNA-damage response factors
O Fernandez-Capetillo, A Celeste, A Nussenzweig
Cell cycle 2 (5), 425-426, 2003
2252003
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20