Biallelic Inactivation of BRCA2 in Fanconi Anemia NG Howlett, T Taniguchi, S Olson, B Cox, Q Waisfisz, C de Die-Smulders, ... Science 297 (5581), 606-609, 2002 | 1455 | 2002 |
The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability NG Howlett, T Taniguchi, SG Durkin, AD D'Andrea, TW Glover Human molecular genetics 14 (5), 693-701, 2005 | 327 | 2005 |
Induction of lipid peroxidation during heavy metal stress in Saccharomyces cerevisiae and influence of plasma membrane fatty acid unsaturation NG Howlett, SV Avery Applied and environmental microbiology 63 (8), 2971-2976, 1997 | 319 | 1997 |
Copper toxicity towards Saccharomyces cerevisiae: dependence on plasma membrane fatty acid composition SV Avery, NG Howlett, S Radice Applied and Environmental Microbiology 62 (11), 3960-3966, 1996 | 288 | 1996 |
FANCD2 facilitates replication through common fragile sites A Madireddy, ST Kosiyatrakul, RA Boisvert, E Herrera-Moyano, ... Molecular cell 64 (2), 388-404, 2016 | 182 | 2016 |
Recent discoveries in the molecular pathogenesis of the inherited bone marrow failure syndrome Fanconi anemia NE Mamrak, A Shimamura, NG Howlett Blood reviews 31 (3), 93-99, 2017 | 153 | 2017 |
Depletion of CHK1, but not CHK2, induces chromosomal instability and breaks at common fragile sites SG Durkin, MF Arlt, NG Howlett, TW Glover Oncogene 25 (32), 4381-4388, 2006 | 153 | 2006 |
Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links JK Hicks, CL Chute, MT Paulsen, RL Ragland, NG Howlett, Q Guéranger, ... Molecular and cellular biology 30 (5), 1217-1230, 2010 | 145 | 2010 |
Knockdown of zebrafish Fancd2 causes developmental abnormalities via p53-dependent apoptosis TX Liu, NG Howlett, M Deng, DM Langenau, K Hsu, J Rhodes, JP Kanki, ... Developmental cell 5 (6), 903-914, 2003 | 138 | 2003 |
Histone methylation by SETD1A protects nascent DNA through the nucleosome chaperone activity of FANCD2 MR Higgs, K Sato, JJ Reynolds, S Begum, R Bayley, A Goula, A Vernet, ... Molecular cell 71 (1), 25-41. e6, 2018 | 94 | 2018 |
FANCP/SLX4: a Swiss army knife of DNA interstrand crosslink repair KE Cybulski, NG Howlett Cell Cycle 10 (11), 1757-1763, 2011 | 70 | 2011 |
Functional interaction between the Fanconi Anemia D2 protein and proliferating cell nuclear antigen (PCNA) via a conserved putative PCNA interaction motif NG Howlett, JA Harney, MA Rego, FW Kolling, TW Glover Journal of biological chemistry 284 (42), 28935-28942, 2009 | 70 | 2009 |
Relationship between cadmium sensitivity and degree of plasma membrane fatty acid unsaturation in Saccharomyces cerevisiae NG Howlett, SV Avery Applied microbiology and biotechnology 48, 539-545, 1997 | 68 | 1997 |
Yeast DEL assay detects clastogens Z Kirpnick, M Homiski, E Rubitski, M Repnevskaya, N Howlett, J Aubrecht, ... Mutation Research/Genetic Toxicology and Environmental Mutagenesis 582 (1-2 …, 2005 | 58 | 2005 |
p21 promotes error-free replication-coupled DNA double-strand break repair M Mauro, MA Rego, RA Boisvert, F Esashi, F Cavallo, M Jasin, ... Nucleic acids research 40 (17), 8348-8360, 2012 | 54 | 2012 |
Flow cytometric investigation of heterogeneous copper-sensitivity in asynchronously grown Saccharomyces cerevisiae NG Howlett, SV Avery FEMS microbiology letters 176 (2), 379-386, 1999 | 51 | 1999 |
Understanding the histone DNA repair code: H4K20me2 makes its mark KL Paquin, NG Howlett Molecular Cancer Research 16 (9), 1335-1345, 2018 | 45 | 2018 |
Cyclic peptide-capped gold nanoparticles for enhanced siRNA delivery AN Shirazi, KL Paquin, NG Howlett, D Mandal, K Parang Molecules 19 (9), 13319-13331, 2014 | 44 | 2014 |
The Fanconi anemia ID2 complex: dueling saxes at the crossroads RA Boisvert, NG Howlett Cell cycle 13 (19), 2999-3015, 2014 | 42 | 2014 |
Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients NG Howlett, Z Scuric, AD D’Andrea, RH Schiestl DNA repair 5 (2), 251-257, 2006 | 40 | 2006 |