| The somatic genomic landscape of glioblastoma CW Brennan, RGW Verhaak, A McKenna, B Campos, H Noushmehr, ... Cell 155 (2), 462-477, 2013 | 3074 | 2013 |
| Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis HS Phillips, S Kharbanda, R Chen, WF Forrest, RH Soriano, TD Wu, ... Cancer cell 9 (3), 157-173, 2006 | 2777 | 2006 |
| Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma H Noushmehr, DJ Weisenberger, K Diefes, HS Phillips, K Pujara, ... Cancer cell 17 (5), 510-522, 2010 | 2093 | 2010 |
| A randomized trial of bevacizumab for newly diagnosed glioblastoma MR Gilbert, JJ Dignam, TS Armstrong, JS Wefel, DT Blumenthal, ... New England Journal of Medicine 370 (8), 699-708, 2014 | 1975 | 2014 |
| Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer cell 22 (4), 425-437, 2012 | 1358 | 2012 |
| Molecular profiling reveals biologically discrete subsets and pathways of progression in diffuse glioma M Ceccarelli, FP Barthel, TM Malta, TS Sabedot, SR Salama, BA Murray, ... Cell 164 (3), 550-563, 2016 | 1116 | 2016 |
| Structure and mechanism of interleukin-lβ converting enzyme KP Wilson, JAF Black, JA Thomson, EE Kim, JP Griffith, MA Navia, ... Nature 370 (6487), 270-275, 1994 | 1102 | 1994 |
| Nitric oxide synthase complexed with dystrophin and absent from skeletal muscle sarcolemma in Duchenne muscular dystrophy JE Brenman, DS Chao, H Xia, K Aldape, DS Bredt Cell 82 (5), 743-752, 1995 | 1083 | 1995 |
| The transcriptional network for mesenchymal transformation of brain tumours MS Carro, WK Lim, MJ Alvarez, RJ Bollo, X Zhao, EY Snyder, EP Sulman, ... Nature 463 (7279), 318-325, 2010 | 1062 | 2010 |
| Epidemiology and molecular pathology of glioma JA Schwartzbaum, JL Fisher, KD Aldape, M Wrensch Nature clinical practice Neurology 2 (9), 494-503, 2006 | 923 | 2006 |
| Targeted expression of MYCN causes neuroblastoma in transgenic mice WA Weiss, K Aldape, G Mohapatra, BG Feuerstein, JM Bishop The EMBO journal 16 (11), 2985-2995, 1997 | 774 | 1997 |
| DNA methylation-based classification of central nervous system tumours D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ... Nature 555 (7697), 469-474, 2018 | 750 | 2018 |
| Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation W Yang, Y Xia, H Ji, Y Zheng, J Liang, W Huang, X Gao, K Aldape, Z Lu Nature 480 (7375), 118-122, 2011 | 736 | 2011 |
| Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth L Zhang, S Zhang, J Yao, FJ Lowery, Q Zhang, WC Huang, P Li, M Li, ... Nature 527 (7576), 100-104, 2015 | 734 | 2015 |
| Immunologic escape after prolonged progression-free survival with epidermal growth factor receptor variant III peptide vaccination in patients with newly diagnosed glioblastoma JH Sampson, AB Heimberger, GE Archer, KD Aldape, AH Friedman, ... Journal of clinical oncology 28 (31), 4722, 2010 | 709 | 2010 |
| Dose-dense temozolomide for newly diagnosed glioblastoma: a randomized phase III clinical trial MR Gilbert, M Wang, KD Aldape, R Stupp, ME Hegi, KA Jaeckle, ... Journal of clinical oncology 31 (32), 4085, 2013 | 666 | 2013 |
| Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma KPL Bhat, V Balasubramaniyan, B Vaillant, R Ezhilarasan, K Hummelink, ... Cancer cell 24 (3), 331-346, 2013 | 648 | 2013 |
| Cilengitide combined with standard treatment for patients with newly diagnosed glioblastoma with methylated MGMT promoter (CENTRIC EORTC 26071-22072 study): a multicentre … R Stupp, ME Hegi, T Gorlia, SC Erridge, J Perry, YK Hong, KD Aldape, ... The lancet oncology 15 (10), 1100-1108, 2014 | 646 | 2014 |
| Mosaic amplification of multiple receptor tyrosine kinase genes in glioblastoma M Snuderl, L Fazlollahi, LP Le, M Nitta, BH Zhelyazkova, CJ Davidson, ... Cancer cell 20 (6), 810-817, 2011 | 607 | 2011 |
| Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ... Cancer cell 27 (5), 728-743, 2015 | 596 | 2015 |
