| Wnts as ligands: processing, secretion and reception AJ Mikels, R Nusse Oncogene 25 (57), 7461-7468, 2006 | 542 | 2006 |
| Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea R Chai, B Kuo, T Wang, EJ Liaw, A Xia, TA Jan, Z Liu, MM Taketo, ... Proceedings of the National Academy of Sciences 109 (21), 8167-8172, 2012 | 300 | 2012 |
| Helicobacter pylori activates and expands Lgr5+ stem cells through direct colonization of the gastric glands M Sigal, ME Rothenberg, CY Logan, JY Lee, RW Honaker, RL Cooper, ... Gastroenterology 148 (7), 1392-1404. e21, 2015 | 238 | 2015 |
| Secreted Wingless-interacting molecule (Swim) promotes long-range signaling by maintaining Wingless solubility KA Mulligan, C Fuerer, W Ching, M Fish, K Willert, R Nusse Proceedings of the National Academy of Sciences 109 (2), 370-377, 2012 | 212 | 2012 |
| Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis M Sigal, CY Logan, M Kapalczynska, HJ Mollenkopf, H Berger, ... Nature 548 (7668), 451-455, 2017 | 199 | 2017 |
| Paracrine Wnt/β-catenin signaling mediates proliferation of undifferentiated spermatogonia in the adult mouse testis HM Takase, R Nusse Proceedings of the National Academy of Sciences 113 (11), E1489-E1497, 2016 | 139 | 2016 |
| Axin2 marks quiescent hair follicle bulge stem cells that are maintained by autocrine Wnt/β-catenin signaling X Lim, SH Tan, KL Yu, SBH Lim, R Nusse Proceedings of the National Academy of Sciences 113 (11), E1498-E1505, 2016 | 120 | 2016 |
| The nucleotide sequence of the human int‐1 mammary oncogene; evolutionary conservation of coding and non‐coding sequences. A van Ooyen, V Kwee, R Nusse The EMBO journal 4 (11), 2905-2909, 1985 | 118 | 1985 |
| Lineage tracing with Axin2 reveals distinct developmental and adult populations of Wnt/β-catenin–responsive neural stem cells AN Bowman, R Van Amerongen, TD Palmer, R Nusse Proceedings of the National Academy of Sciences 110 (18), 7324-7329, 2013 | 111 | 2013 |
| Mammary tumor induction loci in GR and DBAf mice contain one provirus of the mouse mammary tumor virus R Michalides, R van Nie, R Nusse, NE Hynes, B Groner Cell 23 (1), 165-173, 1981 | 108 | 1981 |
| Next-generation surrogate Wnts support organoid growth and deconvolute frizzled pleiotropy in vivo Y Miao, A Ha, W de Lau, K Yuki, AJM Santos, C You, MH Geurts, ... Cell Stem Cell 27 (5), 840-851. e6, 2020 | 93 | 2020 |
| Paracrine Wnt signaling both promotes and inhibits human breast tumor growth JL Green, J La, KW Yum, P Desai, LW Rodewald, X Zhang, M Leblanc, ... Proceedings of the National Academy of Sciences 110 (17), 6991-6996, 2013 | 90 | 2013 |
| Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue R Ardehali, SR Ali, MA Inlay, OJ Abilez, MQ Chen, TA Blauwkamp, ... Proceedings of the National Academy of Sciences 110 (9), 3405-3410, 2013 | 89 | 2013 |
| Running against the Wnt: How Wnt/β-catenin suppresses adipogenesis TJJ De Winter, R Nusse Frontiers in cell and developmental biology 9, 627429, 2021 | 85 | 2021 |
| A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis KJ Basham, S Rodriguez, AF Turcu, AM Lerario, CY Logan, MR Rysztak, ... Genes & development 33 (3-4), 209-220, 2019 | 84 | 2019 |
| Structural analysis of a 1.7-kilobase mouse mammary tumor virus-specific RNA AJ Van Ooyen, RJ Michalides, R Nusse Journal of Virology 46 (2), 362-370, 1983 | 84 | 1983 |
| Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation T Sugiyama, CM Benitez, A Ghodasara, L Liu, GW McLean, J Lee, ... Proceedings of the national academy of sciences 110 (31), 12691-12696, 2013 | 74 | 2013 |
| Immunologic, virologic, and genetic aspects of mammary tumor virus-induced cell-surface antigens: presence of these antigens and the Thy 1.2 antigen on murine mammary gland and … J Hilgers, J Haverman, R Nusse, WJ Blitterswijk, FJ Cleton, PC Hageman, ... Journal of the National Cancer Institute 54 (6), 1323-1333, 1975 | 70 | 1975 |
| Wnts produced by Osterix-expressing osteolineage cells regulate their proliferation and differentiation SH Tan, K Senarath-Yapa, MT Chung, MT Longaker, JY Wu, R Nusse Proceedings of the National Academy of Sciences 111 (49), E5262-E5271, 2014 | 69 | 2014 |
| Identification of the Mtv-2 gene responsible for the early appearance of mammary tumors in the GR mouse by nucleic acid hybridization R Michalides, LV Deemter, R Nusse, RV Nie Proceedings of the National Academy of Sciences 75 (5), 2368-2372, 1978 | 65 | 1978 |
